2Q7K
The Androgen Receptor Prostate Cancer Mutant H874Y Ligand Binding Domain Bound with Testosterone and an AR 20-30 Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 257 | 30032.1 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor |
| 2 | B (B) | Androgen receptor | polymer | 11 | 1267.4 | 1 | UniProt (P10275) | Homo sapiens (human) | Dihydrotestosterone receptor |
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | TESTOSTERONE | non-polymer | 288.4 | 1 | Chemie (TES) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 663 - 919 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Tyr 874 | His 874 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31299.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 572.6 | |
| All* | Total formula weight | 31872.2 |
