2Q7K
The Androgen Receptor Prostate Cancer Mutant H874Y Ligand Binding Domain Bound with Testosterone and an AR 20-30 Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 257 | 30032.1 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor |
| 2 | B (B) | Androgen receptor | polymer | 11 | 1267.4 | 1 | UniProt (P10275) | Homo sapiens (human) | Dihydrotestosterone receptor |
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | TESTOSTERONE | non-polymer | 288.4 | 1 | Chemie (TES) PubChem (5408) PubChem (3034651) PubChem (6013) PubChem (242356) PubChem (369323) PubChem (638016) PubChem (711503) PubChem (908606) PubChem (908608) PubChem (1312122) PubChem (5701998) PubChem (6432567) PubChem (6541863) PubChem (6954100) PubChem (6954101) PubChem (6976807) PubChem (7048589) PubChem (7213985) PubChem (7213991) PubChem (7985137) PubChem (10108190) PubChem (11861311) PubChem (11862155) PubChem (11869421) PubChem (11869422) PubChem (11869423) PubChem (11870497) PubChem (11890585) PubChem (11890586) PubChem (11920270) PubChem (12304591) PubChem (12304592) PubChem (16220011) PubChem (16758160) PubChem (19615208) PubChem (20848917) PubChem (40469851) PubChem (40785049) PubChem (40785050) PubChem (143796510) PubChem (2825665) PubChem (10204) PubChem (51519) PubChem (71045971) PubChem (51508681) PubChem (908607) PubChem (6925433) PubChem (6994116) PubChem (57094693) PubChem (57185304) PubChem (12304594) PubChem (12304595) PubChem (58483165) PubChem (59847731) PubChem (59859271) PubChem (70987786) PubChem (70987811) PubChem (71045973) PubChem (71051775) PubChem (71085514) PubChem (117072371) PubChem (121384949) PubChem (124711639) PubChem (124711640) PubChem (126527172) PubChem (133562488) PubChem (135012819) PubChem (139228436) PubChem (141791996) PubChem (142296689) PubChem (142774791) PubChem (143701725) PubChem (155332323) PubChem (162460416) PubChem (162931702) PubChem (163788316) PubChem (169085516) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 663 - 919 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Tyr 874 | His 874 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31299.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 572.6 | |
| All* | Total formula weight | 31872.2 |
