8FTF
 
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6PIU
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6PIY
 | | Crystal structure of HCV NS3/4A D168A protease in complex with P4-2 (NR02-61) | | Descriptor: | 1,2-ETHANEDIOL, 1-methylcyclobutyl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, NS3/4A protease, ... | | Authors: | Zephyr, J, Schiffer, C.A. | | Deposit date: | 2019-06-27 | | Release date: | 2020-03-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.862 Å) | | Cite: | Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors.
Mbio, 11, 2020
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8FFI
 | | Structure of tetramerized MapSPARTA upon guide RNA-mediated target DNA binding | | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | | Deposit date: | 2022-12-08 | | Release date: | 2023-08-23 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
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2WFM
 | | Crystal structure of polyneuridine aldehyde esterase mutant (H244A) | | Descriptor: | POLYNEURIDINE ALDEHYDE ESTERASE | | Authors: | Yang, L, Hill, M, Panjikar, S, Wang, M, Stoeckigt, J. | | Deposit date: | 2009-04-08 | | Release date: | 2010-04-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
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6PQN
 | | Crystal structure of HzTransib transposase | | Descriptor: | GLYCEROL, PHOSPHATE ION, Putative DNA-mediated transposase, ... | | Authors: | Liu, C, Yang, Y, Schatz, D.G. | | Deposit date: | 2019-07-09 | | Release date: | 2019-10-09 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
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6PIX
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8FFW
 | | Cryo-EM structure of the GR-Hsp90-FKBP51 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... | | Authors: | Noddings, C.M, Agard, D.A. | | Deposit date: | 2022-12-10 | | Release date: | 2023-11-01 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor.
Nat.Struct.Mol.Biol., 30, 2023
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8FAR
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8FFV
 | | Cryo-EM structure of the GR-Hsp90-FKBP52 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... | | Authors: | Noddings, C.M, Agard, D.A. | | Deposit date: | 2022-12-10 | | Release date: | 2023-11-01 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor.
Nat.Struct.Mol.Biol., 30, 2023
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6O2R
 | | Deacetylated Microtubules | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | | Deposit date: | 2019-02-24 | | Release date: | 2019-05-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Effects of alpha-tubulin acetylation on microtubule structure and stability.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6NZH
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8G17
 | | CryoEM structure of wild-type GAPDH | | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase | | Authors: | Choi, W.Y, Wu, H, Cheng, Y.F. | | Deposit date: | 2023-02-01 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (1.98 Å) | | Cite: | Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8G16
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8G13
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2W6W
 | | Crystal structure of recombinant Sperm Whale Myoglobin under 1atm of Xenon | | Descriptor: | GLYCEROL, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Miele, A.E, Draghi, F, Renzi, F, Sciara, G, Johnson, K.A, Vallone, B, Brunori, M, Savino, C. | | Deposit date: | 2008-12-19 | | Release date: | 2009-04-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Pattern of Cavities in Globins: The Case of Human Hemoglobin.
Biopolymers, 91, 2009
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8G12
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8G15
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8G14
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6OY4
 | | Crystal structure of complex between recombinant Der p 2.0103 and Fab fragment of 7A1 | | Descriptor: | Der p 2 variant 3, Fab fragment of IgG, HEAVY CHAIN, ... | | Authors: | Kapingidza, A.B, Offermann, L.R, Glesner, J, Wunschmann, S, Vailes, L.D, Chapman, M.D.C, Pomes, A, Chruszcz, M. | | Deposit date: | 2019-05-14 | | Release date: | 2019-08-28 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.
J Immunol., 203, 2019
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8FRU
 | | 60S subunit of the Giardia lamblia 80S ribosome | | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. | | Deposit date: | 2023-01-08 | | Release date: | 2024-01-31 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.49 Å) | | Cite: | The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Structure, 32, 2024
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2W72
 | | DEOXYGENATED STRUCTURE OF A DISTAL SITE HEMOGLOBIN MUTANT PLUS XE | | Descriptor: | HUMAN HEMOGLOBIN A, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Miele, A.E, Draghi, F, Sciara, G, Johnson, K.A, Renzi, F, Vallone, B, Brunori, M, Savino, C. | | Deposit date: | 2008-12-19 | | Release date: | 2009-04-28 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.07 Å) | | Cite: | Pattern of Cavities in Globins: The Case of Human Hemoglobin.
Biopolymers, 91, 2009
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2VWT
 | | Crystal structure of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12 - Mg-pyruvate product complex | | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Rea, D, Rakus, J.F, Gerlt, J.A, Fulop, V, Bugg, T.D.H, Roper, D.I. | | Deposit date: | 2008-06-26 | | Release date: | 2008-09-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Crystal Structure and Functional Assignment of Yfau, a Metal Ion Dependent Class II Aldolase from Escherichia Coli K12.
Biochemistry, 47, 2008
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2OQR
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2X65
 | | Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with mannose-1-phosphate. | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-O-phosphono-alpha-D-mannopyranose, ... | | Authors: | Pelissier, M.C, Lesley, S, Kuhn, P, Bourne, Y. | | Deposit date: | 2010-02-15 | | Release date: | 2010-06-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Insights Into the Catalytic Mechanism of Bacterial Guanosine-Diphospho-D-Mannose Pyrophosphorylase and its Regulation by Divalent Ions.
J.Biol.Chem., 285, 2010
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