1L2T
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![BU of 1l2t by Molmil](/molmil-images/mine/1l2t) | Dimeric Structure of MJ0796, a Bacterial ABC Transporter Cassette | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Hypothetical ABC transporter ATP-binding protein MJ0796, ISOPROPYL ALCOHOL, ... | Authors: | Smith, P.C, Karpowich, N, Rosen, J, Hunt, J.F. | Deposit date: | 2002-02-24 | Release date: | 2002-07-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol.Cell, 10, 2002
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7APJ
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![BU of 7apj by Molmil](/molmil-images/mine/7apj) | Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation | Descriptor: | NB41, RAC-alpha serine/threonine-protein kinase,Non-specific serine/threonine protein kinase,RAC-alpha serine/threonine-protein kinase | Authors: | Truebestein, L, Hornegger, H, Leonard, T.A. | Deposit date: | 2020-10-16 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of autoinhibited Akt1 reveals mechanism of PIP 3 -mediated activation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6NMI
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![BU of 6nmi by Molmil](/molmil-images/mine/6nmi) | Cryo-EM structure of the human TFIIH core complex | Descriptor: | CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ... | Authors: | Greber, B.J, Toso, D, Fang, J, Nogales, E. | Deposit date: | 2019-01-10 | Release date: | 2019-03-13 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The complete structure of the human TFIIH core complex. Elife, 8, 2019
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5GGM
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![BU of 5ggm by Molmil](/molmil-images/mine/5ggm) | The NMR structure of calmodulin in CTAB reverse micelles | Descriptor: | CALCIUM ION, Calmodulin, TERBIUM(III) ION | Authors: | Xu, G, Cheng, K, Wu, Q, Liu, M, Li, C. | Deposit date: | 2016-06-16 | Release date: | 2016-09-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The NMR structure of calmodulin in CTAB reverse micelles To Be Published
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7B1G
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![BU of 7b1g by Molmil](/molmil-images/mine/7b1g) | TRPC4 in complex with Calmodulin | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ... | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | Deposit date: | 2020-11-24 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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5G3W
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![BU of 5g3w by Molmil](/molmil-images/mine/5g3w) | Structure of HDAC like protein from Bordetella Alcaligenes in complex with the photoswitchable inhibitor CEW65 | Descriptor: | (2E)-N-hydroxy-3-{4-[(E)-phenyldiazenyl]phenyl}prop-2-enamide, DI(HYDROXYETHYL)ETHER, HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE, ... | Authors: | Kraemer, A, Meyer-Almes, F.J, Yildiz, O. | Deposit date: | 2016-05-02 | Release date: | 2016-11-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors. ACS Infect Dis, 3, 2017
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7VVH
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7VUO
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![BU of 7vuo by Molmil](/molmil-images/mine/7vuo) | |
7VVD
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![BU of 7vvd by Molmil](/molmil-images/mine/7vvd) | |
1KA8
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![BU of 1ka8 by Molmil](/molmil-images/mine/1ka8) | Crystal Structure of the Phage P4 Origin-Binding Domain | Descriptor: | putative P4-specific DNA primase | Authors: | Yeo, H.J, Ziegelin, G, Korolev, S, Calendar, R, Lanka, E, Waksman, G. | Deposit date: | 2001-10-31 | Release date: | 2002-04-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Phage P4 origin-binding domain structure reveals a mechanism for regulation of DNA-binding activity by homo- and heterodimerization of winged helix proteins. Mol.Microbiol., 43, 2002
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7A3Z
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![BU of 7a3z by Molmil](/molmil-images/mine/7a3z) | OSM-3 kinesin motor domain complexed with Mg.ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Osmotic avoidance abnormal protein 3 | Authors: | Varela, F.P, Menetrey, J, Gigant, B. | Deposit date: | 2020-08-19 | Release date: | 2021-02-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.095 Å) | Cite: | Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism. Febs Open Bio, 11, 2021
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6NZ2
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1K8X
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![BU of 1k8x by Molmil](/molmil-images/mine/1k8x) | Crystal Structure Of AlphaT183V Mutant Of Tryptophan Synthase From Salmonella Typhimurium | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ... | Authors: | Kulik, V, Weyand, M, Siedel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I. | Deposit date: | 2001-10-26 | Release date: | 2002-12-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | On the Role of AlphaThr183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase J.Mol.Biol., 324, 2002
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7CUM
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![BU of 7cum by Molmil](/molmil-images/mine/7cum) | Cryo-EM structure of human GABA(B) receptor bound to the antagonist CGP54626 | Descriptor: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | Deposit date: | 2020-08-23 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
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4Z8L
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![BU of 4z8l by Molmil](/molmil-images/mine/4z8l) | Crystal structure of DCAF1/SIV-MND VPX/MND SAMHD1 NTD ternary complex | Descriptor: | Protein VPRBP, SAM domain and HD domain-containing protein, Vpx protein, ... | Authors: | Koharudin, L.M, Wu, Y, Calero, G, Ahn, J, Gronenborn, A.M. | Deposit date: | 2015-04-09 | Release date: | 2015-06-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile alpha Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors. J.Biol.Chem., 290, 2015
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6W89
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![BU of 6w89 by Molmil](/molmil-images/mine/6w89) | Structure of DNMT3A (R882H) in complex with CGA DNA | Descriptor: | CGA DNA (25-MER), CITRIC ACID, DNA (cytosine-5)-methyltransferase 3-like, ... | Authors: | Anteneh, H, Song, J. | Deposit date: | 2020-03-20 | Release date: | 2020-04-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Nat Commun, 11, 2020
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5WMF
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5LI3
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![BU of 5li3 by Molmil](/molmil-images/mine/5li3) | Crystal structure of HDAC-like protein from P. aeruginosa in complex with a photo-switchable inhibitor. | Descriptor: | (2E)-N-hydroxy-3-{4-[(E)-(1,3,5-trimethyl-1H-pyrazol-4-yl)diazenyl]phenyl}prop-2-enamide, Acetoin utilization protein, POTASSIUM ION, ... | Authors: | Kraemer, A, Meyer-Almes, F.J, Yildiz, O. | Deposit date: | 2016-07-14 | Release date: | 2016-11-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors. ACS Infect Dis, 3, 2017
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8FZY
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2H0J
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![BU of 2h0j by Molmil](/molmil-images/mine/2h0j) | Crystal structure of PucM in the presence of 5,6-diaminouracil | Descriptor: | 5,6-DIAMINOPYRIMIDINE-2,4(1H,3H)-DIONE, Transthyretin-like protein pucM | Authors: | Rhee, S. | Deposit date: | 2006-05-15 | Release date: | 2006-06-27 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and functional analysis of PucM, a hydrolase in the ureide pathway and a member of the transthyretin-related protein family. Proc.Natl.Acad.Sci.Usa, 103, 2006
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6B8N
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6WA9
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![BU of 6wa9 by Molmil](/molmil-images/mine/6wa9) | |
6OS4
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![BU of 6os4 by Molmil](/molmil-images/mine/6os4) | Calmodulin in complex with farnesyl cysteine methyl ester | Descriptor: | CALCIUM ION, Calmodulin-1, s-farnesyl-l-cysteine methyl ester | Authors: | Grant, B.M.M, Enomoto, M, Lee, K.Y, Back, S.I, Gebregiworgis, T, Ishiyama, N, Ikura, M, Marshall, C. | Deposit date: | 2019-05-01 | Release date: | 2020-04-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety. Sci.Signal., 13, 2020
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1KYC
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6VTZ
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![BU of 6vtz by Molmil](/molmil-images/mine/6vtz) | |