5EF0
 
 | | RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 16.7 MGy | | Descriptor: | (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB | | Authors: | Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B. | | Deposit date: | 2015-10-23 | | Release date: | 2016-05-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
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5EEU
 | | RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 1.31 MGy | | Descriptor: | (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB | | Authors: | Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B. | | Deposit date: | 2015-10-23 | | Release date: | 2016-05-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
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8JE5
 | | Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with Halofuginone | | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, CHLORIDE ION, GLYCEROL, ... | | Authors: | Goswami, R, Manickam, Y, Chhibber-Goel, J, Harlos, K, Sharma, A. | | Deposit date: | 2023-05-15 | | Release date: | 2024-11-27 | | Last modified: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Chemical targeting of prolyl-tRNA synthetase stalls ovarian development and kills malaria vectors.
J.Infect.Dis., 2025
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8JE7
 | | Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with two inhibitors (Halofuginone and L95) | | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, BROMIDE ION, CHLORIDE ION, ... | | Authors: | Goswami, R, Manickam, Y, Chhibber-Goel, J, Harlos, K, Sharma, A. | | Deposit date: | 2023-05-15 | | Release date: | 2024-11-27 | | Last modified: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Chemical targeting of prolyl-tRNA synthetase stalls ovarian development and kills malaria vectors.
J.Infect.Dis., 2025
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5EF3
 | | RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 25.0 MGy | | Descriptor: | (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB | | Authors: | Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B. | | Deposit date: | 2015-10-23 | | Release date: | 2016-05-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
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5EF1
 | | RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 19.3 MGy | | Descriptor: | (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB | | Authors: | Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B. | | Deposit date: | 2015-10-23 | | Release date: | 2016-05-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
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5IJX
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5GL7
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7P6X
 | | Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | | Authors: | Llorca, O, Serna, M, Fernandez-Leiro, R. | | Deposit date: | 2021-07-18 | | Release date: | 2021-12-15 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.
Nucleic Acids Res., 50, 2022
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6J93
 | | Crystal structure of Peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.95 A resolution | | Descriptor: | 1,2-ETHANEDIOL, Peptidyl-tRNA hydrolase | | Authors: | Viswanathan, V, Sharma, P, Singh, P.K, Iqbal, N, Sharma, S, Singh, T.P. | | Deposit date: | 2019-01-21 | | Release date: | 2019-02-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Crystal structure of Peptidyl-tRNA hydrolase form apo at 0.95 A resolution.
To Be Published
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7YP8
 | | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Leucyl-sulfamoyl 3-deazaadenosine | | Descriptor: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | | Authors: | Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. | | Deposit date: | 2022-08-02 | | Release date: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The essential role of a structured water in base recognition of Class II aminoacyl-tRNA synthetases
To be published
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8C49
 | | Crystal structure of pyrrolysyl-tRNA synthetase from Methanomethylophilus alvus engineered for 3-Methyl-L-histidine, bound to AMPPNP | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | Authors: | Hardy, F.J, Levy, C.W. | | Deposit date: | 2023-01-03 | | Release date: | 2023-07-19 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.
Protein Sci., 32, 2023
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4YYE
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4KR6
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8I3Q
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4KR7
 | | Crystal structure of a 4-thiouridine synthetase - RNA complex with bound ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable tRNA sulfurtransferase, ... | | Authors: | Neumann, P, Ficner, R, Lakomek, K. | | Deposit date: | 2013-05-16 | | Release date: | 2014-04-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.421 Å) | | Cite: | Crystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification.
Nucleic Acids Res., 42, 2014
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4KR9
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8S00
 | | CpKRS complexed with lysine and an inhibitor | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-oxidanyl-~{N}-[(1-oxidanylcyclohexyl)methyl]-4-oxidanylidene-chromene-2-carboxamide, GLYCEROL, ... | | Authors: | Dawson, A, Baragana, B, Caldwell, N. | | Deposit date: | 2024-02-13 | | Release date: | 2024-11-06 | | Last modified: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.
Sci Transl Med, 16, 2024
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4XJN
 | | Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity | | Descriptor: | LEAD (II) ION, Nucleocapsid, RNA (78-MER) | | Authors: | Alayyoubi, M, Leser, G.P, Kors, C.A, Lamb, R.A. | | Deposit date: | 2015-01-08 | | Release date: | 2015-03-18 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.11 Å) | | Cite: | Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6IX6
 | | Crystal structure of the complex of peptidyl-tRNA hydrolase with N-propanol at 1.43 A resolution | | Descriptor: | N-PROPANOL, Peptidyl-tRNA hydrolase | | Authors: | Viswanathan, V, Sharma, P, Chaudhary, A, Sharma, S, Singh, T.P. | | Deposit date: | 2018-12-09 | | Release date: | 2018-12-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Crystal structure of the complex of peptidyl-tRNA hydrolase with N-propanol at 1.43 A resolution
To Be Published
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6JKX
 | | Crystal structure of peptidyl-tRNA hydrolase with multiple sodium and chloride ions at 1.08 A resolution. | | Descriptor: | CHLORIDE ION, METHANOL, Peptidyl-tRNA hydrolase, ... | | Authors: | Viswanathan, V, Sharma, P, Bhushan, A, Sharma, S, Singh, T.P. | | Deposit date: | 2019-03-03 | | Release date: | 2019-03-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.08 Å) | | Cite: | Crystal structure of peptidyl-tRNA hydrolase with multiple sodium and chloride ions at 1.08 A resolution.
To Be Published
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6JJ1
 | | Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-tRNA hydrolase | | Authors: | Iqbal, N, Sharma, P, Chaudhary, A, Sharma, S, Singh, T.P. | | Deposit date: | 2019-02-24 | | Release date: | 2019-03-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (0.97 Å) | | Cite: | Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues
To Be Published
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6JJQ
 | | Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.99 A resolution. | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Peptidyl-tRNA hydrolase, ... | | Authors: | Viswanathan, V, Bairagya, H.R, Sharma, P, Sharma, S, Singh, T.P. | | Deposit date: | 2019-02-26 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (0.99 Å) | | Cite: | Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.99 A resolution.
To Be Published
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5ZZV
 | | Crystal structure of PEG-1500 crystallized Peptidyl-tRNA Hydrolase from Acinetobacter baumannii at 1.5 A resolution | | Descriptor: | 1,2-ETHANEDIOL, Peptidyl-tRNA hydrolase | | Authors: | Bairagya, H.R, Sharma, P, Iqbal, N, Sharma, S, Singh, T.P. | | Deposit date: | 2018-06-04 | | Release date: | 2018-06-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Crystal structure of PEG-1500 crystallized Peptidyl-tRNA Hydrolase from Acinetobacter baumannii at 1.5 A resolution
To Be Published
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5YYM
 | | Crystal structures of E.coli arginyl-trna synthetase (argrs) in complex with substrate Arg | | Descriptor: | ARGININE, Arginine--tRNA ligase | | Authors: | Zhou, M, Ye, S, Stephen, P, Zhang, R.G, Wang, E.D, Giege, R, Lin, S.X. | | Deposit date: | 2017-12-10 | | Release date: | 2018-12-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structures Of E.Coli Arginyl-Trna Synthetase (Argrs) In Complex With Substrates
To Be Published
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