7YP8

Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Leucyl-sulfamoyl 3-deazaadenosine

Summary for 7YP8

• Entry DOI: 10.2210/pdb7yp8/pdb
• Descriptor: Leucine--tRNA ligase, 1,2-ETHANEDIOL, [(2R,3S,4R,5R)-5-(4-azanylimidazo[4,5-c]pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl N-[(2S)-2-azanyl-4-methyl-pentanoyl]sulfamate, ... (6 entities in total)
• Functional Keywords: protein-inhibitor complex, rossmann fold, trna synthetase, ligase
• Biological source: Neisseria gonorrhoeae (strain NCCP11945)
• Total number of polymer chains: 1
• Total formula weight: 98795.61

Authors

Pang, L.,De Graef, S.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2022-08-02, release date: 2024-02-07)

• Primary citation: Pang, L.,De Graef, S.,Zhang, B.,Strelkov, S.V.,Van Aerschot, A.,Weeks, S.D.; The essential role of a structured water in base recognition of Class II aminoacyl-tRNA synthetases; To be published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)