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8XM7
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BU of 8xm7 by Molmil
Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex: RhoG/DOCK5/ELMO1 focused map
Descriptor: Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M.
Deposit date:2023-12-27
Release date:2024-06-26
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.91 Å)
Cite:RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.
J.Biol.Chem., 300, 2024
8XM5
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BU of 8xm5 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-27
Release date:2024-07-03
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 2024
8XM2
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BU of 8xm2 by Molmil
The mutant crystal structure of phytase APPAmut9 from Yersinia intermedia
Descriptor: Phytase
Authors:Tu, T, Dong, R.Y.
Deposit date:2023-12-27
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The mutant crystal structure of phytase APPAmut9 from Yersinia intermedia
To Be Published
8XM1
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BU of 8xm1 by Molmil
Phytase mutant APPAmut4
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Phytase
Authors:Tu, T, Wang, Q.
Deposit date:2023-12-27
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The mutant crystal structure of phytase APPAmut4 from Yersinia intermedia
To Be Published
8XLV
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BU of 8xlv by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-26
Release date:2024-07-03
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 2024
8XLQ
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BU of 8xlq by Molmil
FGFR4 kinase domain with a dual-warhead covalent inhibitor CXF-007
Descriptor: CXF007, Fibroblast growth factor receptor 4, SULFATE ION
Authors:Chen, X.J, Chen, Y.H.
Deposit date:2023-12-26
Release date:2024-03-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4.
Eur.J.Med.Chem., 268, 2024
8XLP
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BU of 8xlp by Molmil
Structure of inactive Photosystem II associated with CAC antenna from Rhodomonas Salina
Descriptor: (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ...
Authors:Si, L, Li, M.
Deposit date:2023-12-26
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structure of inactive Photosystem II associated with CAC antenna from Rhodomonas Salina
To Be Published
8XLO
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FGFR1 kinase domain with a dual-warhead covalent inhibitor CXF-007
Descriptor: CXF007, Fibroblast growth factor receptor 1, SULFATE ION
Authors:Chen, X.J, Chen, Y.H.
Deposit date:2023-12-26
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4.
Eur.J.Med.Chem., 268, 2024
8XLN
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BU of 8xln by Molmil
Structure of the SARS-CoV-2 EG.5.1 spike RBD in complex with ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K.
Deposit date:2023-12-26
Release date:2024-05-01
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant.
Microbiol Immunol, 2024
8XLM
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BU of 8xlm by Molmil
Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein in complex with ACE2 (1-up state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K.
Deposit date:2023-12-26
Release date:2024-05-01
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant.
Microbiol Immunol, 2024
8XLD
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BU of 8xld by Molmil
Structure of the GFP:GFP-nanobody complex from Biortus.
Descriptor: 1,2-ETHANEDIOL, Nanobody(Staygold-S2G10)-Nanobody(Staygold-S4F1), ZINC ION, ...
Authors:Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C.
Deposit date:2023-12-25
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the GFP:GFP-nanobody complex from Biortus.
To Be Published
8XKN
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BU of 8xkn by Molmil
Cryo-EM structure of tail tube protein
Descriptor: a protein
Authors:Zhang, H, Li, Z, Li, X.Z.
Deposit date:2023-12-23
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Insights into the modulation of bacterial NADase activity by phage proteins.
Nat Commun, 15, 2024
8XKL
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BU of 8xkl by Molmil
Structure of ACPII-CCPII from cryptophyte algae
Descriptor: (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ...
Authors:Li, X.Y, Mao, Z.Y, Shen, J.R, Han, G.Y.
Deposit date:2023-12-23
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Structure and distinct supramolecular organization of a PSII-ACPII dimer from a cryptophyte alga Chroomonas placoidea.
Nat Commun, 15, 2024
8XKI
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BU of 8xki by Molmil
A neutralizing nanobody VHH60 against wt SARS-CoV-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Lu, Y, Guo, H, Ji, X, Yang, H.
Deposit date:2023-12-23
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug.
Cell Death Dis, 15, 2024
8XKG
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BU of 8xkg by Molmil
Crystal structure of Acinetobacter baumannii IspD
Descriptor: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, GLYCEROL
Authors:Chen, X, Wu, D.
Deposit date:2023-12-23
Release date:2024-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes.
Int J Antimicrob Agents, 63, 2024
8XKF
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BU of 8xkf by Molmil
Crystal structure of Helicobacter pylori IspDF with substrate CTP
Descriptor: 1,2-ETHANEDIOL, Bifunctional enzyme IspD/IspF, CHLORIDE ION, ...
Authors:Chen, X, Wu, D.
Deposit date:2023-12-23
Release date:2024-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes.
Int J Antimicrob Agents, 63, 2024
8XKE
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BU of 8xke by Molmil
The structure of HLA-A/14-3-D
Descriptor: Beta-2-microglobulin, GLU-VAL-ASP-ASN-ALA-THR-ARG-PHE-ALA-SER-VAL-TYR, HLA class I heavy chain
Authors:Zhang, J.N, Yue, C, Liu, J, Sun, Z.Y.
Deposit date:2023-12-23
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
8XKC
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BU of 8xkc by Molmil
The structure of HLA-A/Pep16
Descriptor: Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1
Authors:Zhang, J.N, Yue, C, Liu, J.
Deposit date:2023-12-23
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
8XK8
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BU of 8xk8 by Molmil
N1D10 Fab bound to SFTSV glycoprotein-Gn
Descriptor: Envelopment polyprotein, mAb N1D10 Fab heavy chain, mAb N1D10 Fab light chain
Authors:Zhao, H, Deng, Z.
Deposit date:2023-12-22
Release date:2024-07-10
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
To Be Published
8XK6
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BU of 8xk6 by Molmil
S2A5 Fab bound to SFTSV glycoprotein Gn
Descriptor: Envelopment polyprotein, mAb S2A5 Fab heavy chain, mAb S2A5 Fab light chain
Authors:Deng, Z.
Deposit date:2023-12-22
Release date:2024-07-10
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
To Be Published
8XK5
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BU of 8xk5 by Molmil
SNB1G11 Fab bound to SFTSV glycoprotein Gn
Descriptor: Envelopment polyprotein, mAb SNB1G11 Fab heavy chain, mAb SNB1G11 Fab light chain
Authors:Deng, Z.
Deposit date:2023-12-22
Release date:2024-07-10
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
To Be Published
8XK2
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BU of 8xk2 by Molmil
A neutralizing nanobody VHH60 against wt SARS-CoV-2
Descriptor: Spike protein S1, VHH60 nanobody
Authors:Lu, Y, Guo, H, Ji, X, Yang, H.
Deposit date:2023-12-22
Release date:2024-07-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug.
Cell Death Dis, 15, 2024
8XJO
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BU of 8xjo by Molmil
U46619 bound Thromboxane A2 receptor-Gq Protein Complex
Descriptor: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8XJN
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BU of 8xjn by Molmil
Cloprosetnol bound Thromboxane A2 receptor-Gq Protein Complex
Descriptor: (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8XJM
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BU of 8xjm by Molmil
Latanoprost acid bound Prostaglandin F2-alpha receptor-Gq Protein Complex
Descriptor: Antibody fragment scFv16, Engineered miniGq, Fusion tag,Prostaglandin F2-alpha receptor,LgBiT, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024

223790

數據於2024-08-14公開中

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