1CAH
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7LT3
| NHEJ Long-range synaptic complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ... | Authors: | He, Y, Chen, S. | Deposit date: | 2021-02-18 | Release date: | 2021-04-14 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of long-range to short-range synaptic transition in NHEJ. Nature, 593, 2021
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3I2T
| Crystal structure of the unliganded Drosophila Epidermal Growth Factor Receptor ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ... | Authors: | Alvarado, D, Klein, D.E, Lemmon, M.A. | Deposit date: | 2009-06-29 | Release date: | 2009-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor. Nature, 461, 2009
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5KHU
| Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B. | Deposit date: | 2016-06-15 | Release date: | 2016-09-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. Mol.Cell, 63, 2016
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7LSY
| NHEJ Short-range synaptic complex | Descriptor: | DNA (26-MER), DNA (5'-D(P*CP*AP*AP*TP*GP*AP*AP*AP*CP*GP*GP*AP*AP*CP*AP*GP*TP*CP*AP*G)-3'), DNA (5'-D(P*GP*TP*TP*CP*TP*TP*AP*GP*TP*AP*TP*AP*TP*A)-3'), ... | Authors: | He, Y, Chen, S. | Deposit date: | 2021-02-18 | Release date: | 2021-04-14 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | Structural basis of long-range to short-range synaptic transition in NHEJ. Nature, 593, 2021
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1YGE
| LIPOXYGENASE-1 (SOYBEAN) AT 100K | Descriptor: | FE (III) ION, LIPOXYGENASE-1 | Authors: | Minor, W, Steczko, J, Stec, B, Otwinowski, Z, Bolin, J.T, Walter, R, Axelrod, B. | Deposit date: | 1996-06-04 | Release date: | 1997-07-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution. Biochemistry, 35, 1996
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4O8F
| Crystal Structure of the complex between PPARgamma mutant R357A and rosiglitazone | Descriptor: | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Peroxisome proliferator-activated receptor gamma | Authors: | Pochetti, G, Montanari, R, Capelli, D, Chiaraluce, R, Consalvi, V, Lori, C, Loiodice, F, Laghezza, A, Pasquo, A, Cervoni, L, Aschi, M. | Deposit date: | 2013-12-27 | Release date: | 2014-07-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of the transactivation deficiency of the human PPAR gamma F360L mutant associated with familial partial lipodystrophy. Acta Crystallogr.,Sect.D, 70, 2014
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2RTK
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3UAS
| Cytochrome P450 2B4 covalently bound to the mechanism-based inactivator 9-ethynylphenanthrene | Descriptor: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Gay, S.C, Zhang, H, Shah, M.B, Stout, C.D, Halpert, J.R, Hollenberg, P.F. | Deposit date: | 2011-10-21 | Release date: | 2013-01-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.939 Å) | Cite: | Potent Mechanism-Based Inactivation of Cytochrome P450 2B4 by 9-Ethynylphenanthrene: Implications for Allosteric Modulation of Cytochrome P450 Catalysis. Biochemistry, 52, 2013
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6I5C
| Long wavelength native-SAD phasing of Tubulin-Stathmin-TTL complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M. | Deposit date: | 2018-11-13 | Release date: | 2019-03-13 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Long-wavelength native-SAD phasing: opportunities and challenges. Iucrj, 6, 2019
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6AIM
| Cab2 mutant H337A complex with phosphopantothenate-cysteine | Descriptor: | N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl-L-cysteine, Phosphopantothenate--cysteine ligase CAB2 | Authors: | Zheng, P, Zhu, Z. | Deposit date: | 2018-08-24 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae. J. Mol. Biol., 431, 2019
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8BST
| Crystal structure of the kainate receptor GluK3-H523A ligand binding domain in complex with kainate at 2.7A resolution | Descriptor: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ACETATE ION, CHLORIDE ION, ... | Authors: | Venskutonyte, R, Frydenvang, K, Kastrup, J.S. | Deposit date: | 2022-11-26 | Release date: | 2023-12-13 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. Febs J., 291, 2024
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2RTL
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2FY3
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6Y3J
| RING-DTC domains of Deltex 2, bound to ADP-ribose | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Probable E3 ubiquitin-protein ligase DTX2, ZINC ION | Authors: | Gabrielssen, M, Buetow, L, Huang, D.T. | Deposit date: | 2020-02-18 | Release date: | 2020-09-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination. Sci Adv, 6, 2020
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2RTI
| STREPTAVIDIN-GLYCOLURIL COMPLEX, PH 2.50, SPACE GROUP I222 | Descriptor: | FORMIC ACID, GLYCOLURIL, STREPTAVIDIN | Authors: | Katz, B.A. | Deposit date: | 1997-09-11 | Release date: | 1998-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2RTD
| STREPTAVIDIN-BIOTIN COMPLEX, PH 1.39, SPACE GROUP I222 | Descriptor: | BIOTIN, STREPTAVIDIN | Authors: | Katz, B.A. | Deposit date: | 1997-09-11 | Release date: | 1998-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2RTR
| STREPTAVIDIN-2-IMINOBIOTIN COMPLEX, PH 4.0, SPACE GROUP I222 | Descriptor: | 2-IMINOBIOTIN, STREPTAVIDIN | Authors: | Katz, B.A. | Deposit date: | 1997-09-11 | Release date: | 1998-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2ZK1
| Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2 | Descriptor: | (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. | Deposit date: | 2008-03-12 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
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2ZK4
| Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 15-oxo-eicosatetraenoic acid | Descriptor: | (5E,8E,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. | Deposit date: | 2008-03-12 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
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6Y22
| RING-DTC domains of Deltex 2, Form 1 | Descriptor: | Probable E3 ubiquitin-protein ligase DTX2, ZINC ION | Authors: | Gabrielssen, M, Buetow, L, Huang, D.T. | Deposit date: | 2020-02-14 | Release date: | 2020-09-02 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.069 Å) | Cite: | DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination. Sci Adv, 6, 2020
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2RTO
| STREPTAVIDIN-2-IMINOBIOTIN COMPLEX, PH 2.6, SPACE GROUP I222 | Descriptor: | 2-IMINOBIOTIN, STREPTAVIDIN | Authors: | Katz, B.A. | Deposit date: | 1997-09-11 | Release date: | 1998-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2RTG
| STREPTAVIDIN-BIOTIN COMPLEX, PH 2.40, SPACE GROUP I222 | Descriptor: | BIOTIN, CHLORIDE ION, STREPTAVIDIN, ... | Authors: | Katz, B.A. | Deposit date: | 1997-09-11 | Release date: | 1998-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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2RTQ
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2RTC
| APOSTREPTAVIDIN, PH 3.60, SPACE GROUP I222 | Descriptor: | STREPTAVIDIN, SULFATE ION | Authors: | Katz, B.A. | Deposit date: | 1997-09-11 | Release date: | 1998-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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