PDB: 72960 resultsInfo pagesStatus searchChemie searchBIRD

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7PCU	Crystal structure of YTHDF1 YTH domain in complex with ebselen Descriptor: N-phenyl-2-selanylbenzamide, YTH domain-containing family protein 1 Authors: Dalle Vedove, A, Cazzanelli, G, Quattrone, A, Provenzani, A, Lolli, G. Deposit date: 2021-08-04 Release date: 2022-12-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs. Acs Pharmacol Transl Sci, 5, 2022
5XJQ	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1(1-82)/D2/F/E/G from Human Descriptor: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... Authors: Yi, H, Zhang, R. Deposit date: 2017-05-04 Release date: 2018-07-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.28 Å) Cite: Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly. Nucleic Acids Res., 2019
7APK	Structure of the human THO - UAP56 complex Descriptor: Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... Authors: Hohmann, U, Puehringer, T, Plaschka, C. Deposit date: 2020-10-17 Release date: 2020-12-16 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structure of the human core transcription-export complex reveals a hub for multivalent interactions. Elife, 9, 2020
1FC8	NMR SOLUTION STRUCTURE OF A CHIMERIC OLIGONUCLEOTIDE HAIRPIN R(GGAC)D(TTCG)2'F-A(GTCC) Descriptor: 5'-R(*GP*GP*AP*CP)D(*TP*TP*CP*GP*(GFL)P*(TAF)P*(CFL)P*(CFL))-3' Authors: Trempe, J.-F, Gehring, K. Deposit date: 2000-07-18 Release date: 2001-05-30 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes. J.Am.Chem.Soc., 123, 2001
7QKN	Crystal structure of YTHDF1 YTH domain in complex with the ebsulfur derivative compound 7 Descriptor: 1,2-ETHANEDIOL, THIOCYANATE ION, YTH domain-containing family protein 1, ... Authors: Dalle Vedove, A, Cazzanelli, G, Quattrone, A, Provenzani, A, Lolli, G. Deposit date: 2021-12-18 Release date: 2022-11-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs. Acs Pharmacol Transl Sci, 5, 2022
7QL7	Crystal structure of YTHDF1 YTH domain in complex with the ebsulfur derivative compound 9 Descriptor: 1,2-ETHANEDIOL, THIOCYANATE ION, YTH domain-containing family protein 1, ... Authors: Dalle Vedove, A, Cazzanelli, G, Quattrone, A, Provenzani, A, Lolli, G. Deposit date: 2021-12-19 Release date: 2022-11-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs. Acs Pharmacol Transl Sci, 5, 2022
6OWJ	Zn-mediated polymerization of human SFPQ Descriptor: Splicing factor, proline- and glutamine-rich, ZINC ION Authors: Lee, M. Deposit date: 2019-05-10 Release date: 2020-02-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ. Nucleic Acids Res., 48, 2020
6WAZ	+1 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state) Descriptor: HIV-1 viral RNA genome fragment, Reverse transcriptase p51 subunit, Reverse transcriptase/ribonuclease H, ... Authors: Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Puglisi, E.V. Deposit date: 2020-03-26 Release date: 2020-06-24 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription. J.Mol.Biol., 432, 2020
3I56	Co-crystal structure of Triacetyloleandomcyin Bound to the Large Ribosomal Subunit Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B. Deposit date: 2009-07-03 Release date: 2010-03-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui. Antimicrob.Agents Chemother., 53, 2009
3MGM	Crystal structure of human NUDT16 Descriptor: U8 snoRNA-decapping enzyme Authors: Yan, J, Lu, G, Zhang, J, Qi, J, Li, Z, Gao, F. Deposit date: 2010-04-07 Release date: 2011-04-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Crystal structure and the template mRNA decapping activity of human NUDT16 To be Published
5IVW	Human core TFIIH bound to DNA within the PIC Descriptor: General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, General transcription factor IIH subunit 4, ... Authors: He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. Deposit date: 2016-03-21 Release date: 2016-05-18 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (10 Å) Cite: Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
1HR0	CRYSTAL STRUCTURE OF INITIATION FACTOR IF1 BOUND TO THE 30S RIBOSOMAL SUBUNIT Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Morgan-Warren, R.J, Wimberly, B.T, Ramakrishnan, V. Deposit date: 2000-12-20 Release date: 2001-01-24 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal structure of an initiation factor bound to the 30S ribosomal subunit. Science, 291, 2001
5ZVG	The crystal structure of NSun6 from Pyrococcus horikoshii with SAM Descriptor: 389aa long hypothetical nucleolar protein, S-ADENOSYLMETHIONINE Authors: Li, J, Liu, R.J, Wang, E.D. Deposit date: 2018-05-10 Release date: 2018-12-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs. Nucleic Acids Res., 47, 2019
5ZVE	The crystal structure of NSun6 from Pyrococcus horikoshii with SAH Descriptor: 389aa long hypothetical nucleolar protein, S-ADENOSYL-L-HOMOCYSTEINE Authors: Li, J, Liu, R.J, Wang, E.D. Deposit date: 2018-05-10 Release date: 2018-12-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.178 Å) Cite: Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs. Nucleic Acids Res., 47, 2019
5XJS	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E from Human Descriptor: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... Authors: Yi, H, Zhang, R. Deposit date: 2017-05-04 Release date: 2018-07-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.38 Å) Cite: Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly. Nucleic Acids Res., 2019
5ZVH	The crystal structure of NSun6 from Pyrococcus horikoshii with SFG Descriptor: 389aa long hypothetical nucleolar protein, SINEFUNGIN Authors: Li, J, Liu, R.J, Wang, E.D. Deposit date: 2018-05-10 Release date: 2018-12-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs. Nucleic Acids Res., 47, 2019
5XJR	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E/G from Human Descriptor: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... Authors: Yi, H, Zhang, R. Deposit date: 2017-05-04 Release date: 2018-07-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.12 Å) Cite: Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly. Nucleic Acids Res., 2019
7QDR	Apo human SKI complex in the closed state Descriptor: Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 Authors: Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. Deposit date: 2021-11-29 Release date: 2022-02-02 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
7QDS	Apo human SKI complex in the open state Descriptor: Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 Authors: Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. Deposit date: 2021-11-30 Release date: 2022-02-02 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
6L3F	The structure of UTP:RNA uridylyltransferase 1 (URT1) in in Arabidopsis Descriptor: UTP:RNA uridylyltransferase 1 Authors: Lingru, Z. Deposit date: 2019-10-10 Release date: 2020-01-29 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.975 Å) Cite: Crystal structure of Arabidopsis terminal uridylyl transferase URT1. Biochem.Biophys.Res.Commun., 524, 2020
5YJJ	Crystal structure of PNPase from Staphylococcus epidermidis Descriptor: MAGNESIUM ION, PHOSPHATE ION, Polyribonucleotide nucleotidyltransferase Authors: Raj, R, Gopal, B. Deposit date: 2017-10-10 Release date: 2018-01-31 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Characterization of Staphylococcus epidermidis Polynucleotide phosphorylase and its interactions with ribonucleases RNase J1 and RNase J2. Biochem. Biophys. Res. Commun., 495, 2018
6WB0	+3 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state) Descriptor: HIV-1 viral RNA genome fragment, Reverse transcriptase/ribonuclease H, reverse transcriptase p51 subunit, ... Authors: Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Puglisi, E.V. Deposit date: 2020-03-26 Release date: 2020-06-24 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription. J.Mol.Biol., 432, 2020
6WB1	+3 extended HIV-1 reverse transcriptase initiation complex core (intermediate state) Descriptor: HIV-1 viral RNA genome fragment, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, reverse transcriptase p51 subunit, ... Authors: Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Chen, D.H, Puglisi, E.V. Deposit date: 2020-03-26 Release date: 2020-06-24 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription. J.Mol.Biol., 432, 2020
3CD6	Co-cystal of large Ribosomal Subunit mutant G2616A with CC-Puromycin Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... Authors: Blaha, G, Gurel, G. Deposit date: 2008-02-26 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
6WB2	+3 extended HIV-1 reverse transcriptase initiation complex core (displaced state) Descriptor: HIV-1 viral RNA genome fragment, Reverse transcriptase/ribonuclease H, reverse transcriptase p51 subunit, ... Authors: Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Chen, D.H, Puglisi, E.V. Deposit date: 2020-03-26 Release date: 2020-06-24 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription. J.Mol.Biol., 432, 2020

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