PDB: 19260 resultsInfo pagesStatus searchChemie searchBIRD

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3E9D	Structure of full-length TIGAR from Danio rerio Descriptor: PHOSPHATE ION, POTASSIUM ION, Zgc:56074 Authors: Li, H, Jogl, G. Deposit date: 2008-08-21 Release date: 2008-12-16 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: TIGAR (TP53 induced glycolysis and apoptosis regulator) is a fructose-2,6- and fructose-1,6-bisphosphatase To be Published
3EEJ	Candida glabrata Dihydrofolate Reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-phenylphenyl)prop-1-ynyl]-6-methylpyrimidine(UCP111D) and NADPH Descriptor: 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Liu, J, Anderson, A. Deposit date: 2008-09-04 Release date: 2009-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors Chem.Biol.Drug Des., 73, 2009
3EF0	The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase Descriptor: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAFLUOROALUMINATE ION Authors: Ghosh, A, Lima, C.D. Deposit date: 2008-09-07 Release date: 2008-12-02 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The structure of Fcp1, an essential RNA polymerase II CTD phosphatase. Mol.Cell, 32, 2008
3EA7	Crystal structure of SARS-CoV main protease triple mutant STI/A in space group P21 Descriptor: 3C-like proteinase Authors: Shi, J.H, Jayaraman, S, Song, J.X. Deposit date: 2008-08-25 Release date: 2009-09-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Crystal structure of SARS-CoV Mpro mutant To be Published
3DXE	Crystal structure of the intracellular domain of human APP (T668A mutant) in complex with Fe65-PTB2 Descriptor: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1 Authors: Radzimanowski, J, Sinning, I, Wild, K. Deposit date: 2008-07-24 Release date: 2008-09-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2. Embo Rep., 9, 2008
3DXL	Crystal structure of AeD7 from Aedes Aegypti Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Allergen Aed a 2, CHLORIDE ION, ... Authors: Andersen, J.F, Calvo, E, Mans, B.J, Ribeiro, J.M. Deposit date: 2008-07-24 Release date: 2009-02-03 Last modified: 2021-03-31 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Multifunctionality and mechanism of ligand binding in a mosquito antiinflammatory protein Proc.Natl.Acad.Sci.USA, 106, 2009
3DY9	Crystal structure of AeD7 potassium bromide soak Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, D7 protein, ... Authors: Andersen, J.F, Calvo, E, Mans, B.J, Ribeiro, J.M. Deposit date: 2008-07-25 Release date: 2009-02-03 Last modified: 2021-03-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Multifunctionality and mechanism of ligand binding in a mosquito antiinflammatory protein Proc.Natl.Acad.Sci.USA, 106, 2009
3DJ4	Crystal Structure of GlmU from Mycobacterium tuberculosis in complex with URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE. Descriptor: Bifunctional protein glmU, COBALT (II) ION, MAGNESIUM ION, ... Authors: Verma, S.K, Prakash, B. Deposit date: 2008-06-22 Release date: 2009-05-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.38 Å) Cite: PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity. J.Mol.Biol., 386, 2009
3DZR	Thaumatin by Classical hanging drop method before high X-Ray dose on ESRF ID29 beamline Descriptor: L(+)-TARTARIC ACID, Thaumatin-1 Authors: Tripathi, S, Pechkova, E, Nicolini, C. Deposit date: 2008-07-30 Release date: 2009-07-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Radiation damage in protein structural characterization by Synchrotron Radiation: State of the art and Nanotechnology-based perspective To be Published
3DKC	Structure of MET receptor tyrosine kinase in complex with ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Hepatocyte growth factor receptor, ... Authors: Hendle, J. Deposit date: 2008-06-24 Release date: 2009-07-07 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.52 Å) Cite: SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. Mol.Cancer Ther., 8, 2009
3DL0	Crystal structure of adenylate kinase variant AKlse3 Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... Authors: Bannen, R.M, Bianchetti, C.M, Bingman, C.A, McCoy, J.G. Deposit date: 2008-06-26 Release date: 2009-06-09 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Effectiveness and limitations of local structural entropy optimization in the thermal stabilization of mesophilic and thermophilic adenylate kinases. Proteins, 82, 2014
3E1G	Snapshots of esterase D from lactobacillus rhamnosus: Insights into a rotation driven catalytic mechanism Descriptor: DIETHYL PHOSPHONATE, Esterase D Authors: Bennett, M.D, Delabre, M.-L, Holland, R, Norris, G.E. Deposit date: 2008-08-04 Release date: 2009-08-04 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Snapshots of esterase D from lactobacillus rhamnosus: Insights into a rotation driven catalytic mechanism To be Published
3DGE	Structure of a histidine kinase-response regulator complex reveals insights into Two-component signaling and a novel cis-autophosphorylation mechanism Descriptor: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Response regulator, ... Authors: Casino, P, Marina, A. Deposit date: 2008-06-13 Release date: 2009-07-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Insight into Partner Specificity and Phosphoryl Transfer in Two-Component Signal Transduction. Cell(Cambridge,Mass.), 139, 2009
3DO2	Thermolysin by LB nanotemplate method after high X-Ray dose on ESRF ID14-2 beamline Descriptor: CALCIUM ION, LYSINE, Thermolysin, ... Authors: Pechkova, E, Tripathi, S.K, Nicolini, C. Deposit date: 2008-07-03 Release date: 2009-07-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.22 Å) Cite: Radiation damage in protein structural characterization by Synchrotron Radiation: State of the art and Nanotechnology-based perspective To be Published
3DOZ	Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3k Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ... Authors: Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H. Deposit date: 2008-07-07 Release date: 2009-05-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J.Med.Chem., 52, 2009
3DQ0	Maize cytokinin oxidase/dehydrogenase complexed with N6-(3-methoxy-phenyl)adenine Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokinin dehydrogenase 1, ... Authors: Kopecny, D, Briozzo, P. Deposit date: 2008-07-09 Release date: 2009-07-14 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Characterization and biological activity of novel purine-derived inhibitor of cytokinin oxidase/dehydrogenase and its potential use for in vivo studies To be Published
3DQJ	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1000 Atmospheres Number 3: Structure 7 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DRU	Crystal Structure of Gly117Phe Alpha1-Antitrypsin Descriptor: Alpha-1-antitrypsin Authors: Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E. Deposit date: 2008-07-11 Release date: 2009-03-31 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J.Mol.Biol., 387, 2009
3DPD	Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-Dihydro-2H-benzo[1,4]oxazines Descriptor: 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Authors: Ceska, T.A. Deposit date: 2008-07-08 Release date: 2008-08-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines Bioorg.Med.Chem.Lett., 18, 2008
3DT4	The structure of rat cytosolic PEPCK in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DUS	Crystal structure of SAG506-01, orthorhombic, twinned, crystal 1 Descriptor: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ... Authors: Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V. Deposit date: 2008-07-17 Release date: 2008-12-02 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments. Acta Crystallogr.,Sect.D, 64, 2008
3DQI	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1000 Atmospheres Number 4: Structure 8 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DWS	Leishmania major Coproporphyrinogen III Oxidase with bound ligand Descriptor: 5-fluoroindole-2-carboxylic acid, ACETATE ION, Coproporphyrinogen III oxidase Authors: Le Trong, I, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) Deposit date: 2008-07-22 Release date: 2008-09-09 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Leishmania major Coproporphyrinogen III Oxidase with bound ligand To be Published
3DQU	Structure of the Yellow Fluorescent Protein Citrine Frozen at 2000 Atmospheres Number 1: Structure 20 in a Series of 26 High Pressure Structures Descriptor: Green fluorescent protein Authors: Barstow, B, Kim, C.U. Deposit date: 2008-07-09 Release date: 2008-09-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DX3	Golgi alpha-Mannosidase II in complex with Mannostatin analog (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetraol Descriptor: (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetrol, (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Kuntz, D.A, Rose, D.R. Deposit date: 2008-07-23 Release date: 2009-07-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.42 Å) Cite: The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A. Chembiochem, 10, 2009

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