PDB: 11035 resultsInfo pagesStatus searchChemie searchBIRD

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4UB0	New design for monovalent bispecific IgG through cysteine engineering of the CH1-CL interface Descriptor: IgG1, heavy chain, light chain Authors: Oganesyan, V.Y, Dall'Acqua, W.F. Deposit date: 2014-08-11 Release date: 2015-07-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Improving target cell specificity using a novel monovalent bispecific IgG design. Mabs, 7, 2015
4KC8	Crystal Structure of Endo-1,5-alpha-L-arabinanase from Thermotoga petrophila RKU-1 in complex with TRIS Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Glycoside hydrolase, ... Authors: Nascimento, A.F.Z, Polo, C.C, Santos, C.R, Costa, M.C.M.F, Mesa, A.N, Prade, R.A, Ruller, R, Squina, F.M, Murakami, M.T. Deposit date: 2013-04-24 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Mechanistic strategies for catalysis adopted by evolutionary distinct family 43 arabinanases. J.Biol.Chem., 289, 2014
5L6Z	Crystal structure of D62A mutant of Thermotoga maritima TmPEP1050 aminopeptidase Descriptor: CITRIC ACID, SODIUM ION, leucylaminopeptidase Authors: Dutoit, R, Van Elder, D, Bauvois, C. Deposit date: 2016-06-01 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.501 Å) Cite: M42 aminopeptidase catalytic site: the structural and functional role of a strictly conserved aspartate residue Proteins, 2020
6WIB	Next generation monomeric IgG4 Fc Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 4, ZINC ION Authors: Oganesyan, V.Y, Shan, L, Dall'Acqua, W, van Dyk, N. Deposit date: 2020-04-09 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.55 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
6WMH	Next generation monomeric IgG4 Fc Descriptor: Immunoglobulin heavy constant gamma 4 Authors: Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. Deposit date: 2020-04-21 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
6WNA	Next generation monomeric IgG4 Fc Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ... Authors: Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. Deposit date: 2020-04-22 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
6WOL	Next generation monomeric IgG4 Fc bound to neonatal Fc receptor Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... Authors: Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. Deposit date: 2020-04-24 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.49 Å) Cite: In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
7NL2	Structure of Xyn11 from Pseudothermotoga thermarum Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-xylanase, GLYCEROL Authors: Jimenez-Ortega, E, Sanz-Aparicio, J. Deposit date: 2021-02-22 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Phylogenetic, functional and structural characterization of a GH10 xylanase active at extreme conditions of temperature and alkalinity Comput Struct Biotechnol J, 19, 2021
8Y7G	Crystal structure of the Marinitoga sp. Csx1-Crn2 H495A mutant in complex with cyclic-tetraadenylate (cA4) Descriptor: ACETATE ION, CRISPR-associated protein, RNA (5'-R(P*AP*A)-3'), ... Authors: Zhang, D, Yuan, C, Lin, Z. Deposit date: 2024-02-04 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system. Nucleic Acids Res., 2024
8Y6Z	Crystal structure of the Marinitoga sp. Csx1-Crn2 fusion ribonuclease of type III CRISPR Descriptor: CRISPR-associated protein Authors: Zhang, D, Yuan, C. Deposit date: 2024-02-03 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system. Nucleic Acids Res., 2024
8Y75	Crystal structure of the CARF-HTH domain of Csx1-Crn2 from Marinitoga sp. Descriptor: CRISPR-associated protein Authors: Zhang, D, Yuan, C, Lin, Z. Deposit date: 2024-02-03 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system. Nucleic Acids Res., 2024
8Y7F	Crystal structure of CARF domain-truncated Csx1-Crn2 from Marinitoga sp. Descriptor: CRISPR-associated protein Authors: Zhang, D, Yuan, C, Lin, Z. Deposit date: 2024-02-04 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system. Nucleic Acids Res., 2024
1H1C	Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima Descriptor: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE Authors: Vega, M.C, Fernandez, F.J, Wilmanns, M. Deposit date: 2002-07-08 Release date: 2004-03-19 Last modified: 2019-07-24 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem., 279, 2004
5LGF	Solution structure of the N-terminal domain of Ogataea polymorpha telomerase reverse transcriptase Descriptor: Telomerase reverse transcriptase Authors: Polshakov, V.I, Mantsyzov, A.B, Efimov, S.V. Deposit date: 2016-07-07 Release date: 2017-07-19 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase. Nucleic Acids Res., 46, 2018
8BN3	Yeast 80S, ES7s delta, eIF5A, Stm1 containing Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... Authors: Dimitrova-Paternoga, L, Paternoga, H, Wilson, D.N. Deposit date: 2022-11-12 Release date: 2024-01-10 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes. Nucleic Acids Res., 52, 2024
7CTD	Crystal structure of apo form of alpha-glucuronidase (TM0752) from Thermotoga maritima Descriptor: Alpha-glucosidase, putative Authors: Manoj, N, Mohapatra, B.S. Deposit date: 2020-08-18 Release date: 2021-09-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural basis of catalysis and substrate recognition by the NAD(H)-dependent alpha-d-glucuronidase from the glycoside hydrolase family 4. Biochem.J., 478, 2021
7CTL	Crystal structure of NADH bound holo form of alpha-glucuronidase (TM0752) from Thermotoga maritima at 1.97 Angstrom resolution Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alpha-glucosidase, putative Authors: Manoj, N, Mohapatra, B.S. Deposit date: 2020-08-19 Release date: 2021-09-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Structural basis of catalysis and substrate recognition by the NAD(H)-dependent alpha-d-glucuronidase from the glycoside hydrolase family 4. Biochem.J., 478, 2021
7CTM	Crystal structure of Thermotoga maritima alpha-glucuronidase (TM0752) in complex with NADH and D-glucuronic acid Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alpha-glucosidase, putative, ... Authors: Manoj, N, Mohapatra, B.S. Deposit date: 2020-08-19 Release date: 2021-09-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural basis of catalysis and substrate recognition by the NAD(H)-dependent alpha-d-glucuronidase from the glycoside hydrolase family 4. Biochem.J., 478, 2021
2XON	Structure of TmCBM61 in complex with beta-1,4-galactotriose at 1.4 A resolution Descriptor: 1,2-ETHANEDIOL, ARABINOGALACTAN ENDO-1,4-BETA-GALACTOSIDASE, CALCIUM ION, ... Authors: Cid, M, Lodberg-Pedersen, H, Kaneko, S, Coutinho, P.M, Henrissat, B, Willats, W.G.T, Boraston, A.B. Deposit date: 2010-08-20 Release date: 2010-09-08 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Recognition of the Helical Structure of Beta-1,4-Galactan by a New Family of Carbohydrate-Binding Modules. J.Biol.Chem., 285, 2010
8TJF	monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface Descriptor: Fab Lambda light chain, IgG1 Fab heavy chain Authors: Oganesyan, V.Y, van Dyk, N, Mazor, Y, Chiang, C. Deposit date: 2023-07-21 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface. Mabs, 15, 2023
8TI4	monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface Descriptor: GLYCEROL, IgG1 Fab heavy chain, mutated to promote correct pairing, ... Authors: Oganesyan, V.Y, van Dyk, N, Mazor, Y. Deposit date: 2023-07-19 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface. Mabs, 15, 2023
7BYX	Crystal structure of exo-beta-1,3-galactanase from Phanerochaete chrysosporium Pc1,3Gal43A E208A with beta-1,3-galactotriose Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Matsuyama, K, Ishida, T, Kishine, N, Fujimoto, Z, Igarashi, K, Kaneko, S. Deposit date: 2020-04-24 Release date: 2020-11-04 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Unique active-site and subsite features in the arabinogalactan-degrading GH43 exo-beta-1,3-galactanase from Phanerochaete chrysosporium . J.Biol.Chem., 295, 2020
7BYS	Crystal structure of exo-beta-1,3-galactanase from Phanerochaete chrysosporium Pc1,3Gal43A apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CITRIC ACID, ... Authors: Matsuyama, K, Ishida, T, Kishine, N, Fujimoto, Z, Igarashi, K, Kaneko, S. Deposit date: 2020-04-24 Release date: 2020-11-04 Last modified: 2021-01-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Unique active-site and subsite features in the arabinogalactan-degrading GH43 exo-beta-1,3-galactanase from Phanerochaete chrysosporium . J.Biol.Chem., 295, 2020
7BYV	Crystal structure of exo-beta-1,3-galactanase from Phanerochaete chrysosporium Pc1,3Gal43A E208Q with beta-1,3-galactotriose Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Galactan 1,3-beta-galactosidase, ... Authors: Matsuyama, K, Ishida, T, Kishine, N, Fujimoto, Z, Igarashi, K, Kaneko, S. Deposit date: 2020-04-24 Release date: 2020-11-04 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Unique active-site and subsite features in the arabinogalactan-degrading GH43 exo-beta-1,3-galactanase from Phanerochaete chrysosporium . J.Biol.Chem., 295, 2020
7BYT	Crystal structure of exo-beta-1,3-galactanase from Phanerochaete chrysosporium Pc1,3Gal43A with galactose Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... Authors: Matsuyama, K, Ishida, T, Kishine, N, Fujimoto, Z, Igarashi, K, Kaneko, S. Deposit date: 2020-04-24 Release date: 2020-11-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Unique active-site and subsite features in the arabinogalactan-degrading GH43 exo-beta-1,3-galactanase from Phanerochaete chrysosporium . J.Biol.Chem., 295, 2020

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