7ZS9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zs9 by Molmil](/molmil-images/mine/7zs9) | |
8A3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a3d by Molmil](/molmil-images/mine/8a3d) | Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 28S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Faille, A, Warren, A.J, Dent, K.C. | Deposit date: | 2022-06-08 | Release date: | 2023-03-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | The chemical landscape of the human ribosome at 1.67 angstrom resolution. Biorxiv, 2023
|
|
4V9F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v9f by Molmil](/molmil-images/mine/4v9f) | |
6SV4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sv4 by Molmil](/molmil-images/mine/6sv4) | The cryo-EM structure of SDD1-stalled collided trisome. | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R. | Deposit date: | 2019-09-17 | Release date: | 2020-03-04 | Last modified: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1. Nat.Struct.Mol.Biol., 27, 2020
|
|
8OJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oj0 by Molmil](/molmil-images/mine/8oj0) | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | Deposit date: | 2023-03-23 | Release date: | 2024-02-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
|
|
6LQM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lqm by Molmil](/molmil-images/mine/6lqm) | Cryo-EM structure of a pre-60S ribosomal subunit - state C | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | Deposit date: | 2020-01-14 | Release date: | 2020-08-26 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
|
|
8BR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8br8 by Molmil](/molmil-images/mine/8br8) | Giardia ribosome in POST-T state (A1) | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | Deposit date: | 2022-11-22 | Release date: | 2023-03-15 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis. Nucleic Acids Res., 51, 2023
|
|
6T7T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t7t by Molmil](/molmil-images/mine/6t7t) | Structure of yeast 80S ribosome stalled on poly(A) tract. | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | Deposit date: | 2019-10-23 | Release date: | 2019-12-25 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
|
|
7ZUX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zux by Molmil](/molmil-images/mine/7zux) | Collided ribosome in a disome unit from S. cerevisiae | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | Deposit date: | 2022-05-13 | Release date: | 2023-02-22 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
|
|
6T83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t83 by Molmil](/molmil-images/mine/6t83) | Structure of yeast disome (di-ribosome) stalled on poly(A) tract. | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | Deposit date: | 2019-10-24 | Release date: | 2019-12-25 | Last modified: | 2020-02-12 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
|
|
6MTD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mtd by Molmil](/molmil-images/mine/6mtd) | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
|
|
4V9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v9a by Molmil](/molmil-images/mine/4v9a) | Crystal Structure of the 70S ribosome with tetracycline. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Jenner, L, Yusupov, M, Yusupova, G. | Deposit date: | 2012-07-18 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.2999 Å) | Cite: | Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
6MTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mte by Molmil](/molmil-images/mine/6mte) | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
|
|
4V9O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v9o by Molmil](/molmil-images/mine/4v9o) | |
8H69
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h69 by Molmil](/molmil-images/mine/8h69) | Cryo-EM structure of influenza RNA polymerase | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3'), ... | Authors: | Li, H, Wu, Y, Liang, H, Liu, Y. | Deposit date: | 2022-10-16 | Release date: | 2023-06-28 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles. Nat.Struct.Mol.Biol., 30, 2023
|
|
7OZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ozr by Molmil](/molmil-images/mine/7ozr) | |
7ZPQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zpq by Molmil](/molmil-images/mine/7zpq) | Structure of the RQT-bound 80S ribosome from S. cerevisiae (C1) | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | Deposit date: | 2022-04-28 | Release date: | 2023-02-22 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
|
|
7ZRS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zrs by Molmil](/molmil-images/mine/7zrs) | Structure of the RQT-bound 80S ribosome from S. cerevisiae (C2) - composite map | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | Deposit date: | 2022-05-05 | Release date: | 2023-02-22 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
|
|
7LS1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ls1 by Molmil](/molmil-images/mine/7ls1) | 80S ribosome from mouse bound to eEF2 (Class II) | Descriptor: | 28S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Loerch, S, Smith, P.R, Kunder, N, Stanowick, A.D, Lou, T.-F, Campbell, Z.T. | Deposit date: | 2021-02-17 | Release date: | 2021-11-03 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance. Nat Commun, 12, 2021
|
|
7LS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ls2 by Molmil](/molmil-images/mine/7ls2) | 80S ribosome from mouse bound to eEF2 (Class I) | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Loerch, S, Smith, P.R, Kunder, N, Stanowick, A.D, Lou, T.-F, Campbell, Z.T. | Deposit date: | 2021-02-17 | Release date: | 2021-11-03 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance. Nat Commun, 12, 2021
|
|
5WIS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wis by Molmil](/molmil-images/mine/5wis) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with methymycin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution | Descriptor: | (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S Ribosomal RNA, 23S ribosomal RNA, ... | Authors: | Almutairi, M.M, Svetlov, M.S, Hansen, D.A, Khabibullina, N.F, Klepacki, D, Kang, H.Y, Sherman, D.H, Vazquez-Laslop, N, Polikanov, Y.S, Mankin, A.S. | Deposit date: | 2017-07-20 | Release date: | 2018-02-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins. Nucleic Acids Res., 45, 2017
|
|
5WIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wit by Molmil](/molmil-images/mine/5wit) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with pikromycin and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution | Descriptor: | (3R,5R,6S,7S,9R,11E,13S,14R)-14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-2,4,10-trioxo-1-oxacyclotetradec-11-en-6-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Almutairi, M.M, Svetlov, M.S, Hansen, D.A, Khabibullina, N.F, Klepacki, D, Kang, H.Y, Sherman, D.H, Vazquez-Laslop, N, Polikanov, Y.S, Mankin, A.S. | Deposit date: | 2017-07-20 | Release date: | 2018-02-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins. Nucleic Acids Res., 45, 2017
|
|
2B3X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b3x by Molmil](/molmil-images/mine/2b3x) | Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1) | Descriptor: | 1,2-ETHANEDIOL, IRON/SULFUR CLUSTER, Iron-responsive element binding protein 1, ... | Authors: | Dupuy, J, Fontecilla-Camps, J.C, Volbeda, A. | Deposit date: | 2005-09-22 | Release date: | 2006-01-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Crystal structure of human iron regulatory protein 1 as cytosolic aconitase Structure, 14, 2006
|
|
4U67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u67 by Molmil](/molmil-images/mine/4u67) | Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 | Descriptor: | 23s RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A. | Deposit date: | 2014-07-28 | Release date: | 2015-08-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. Structure, 25, 2017
|
|
2B3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b3y by Molmil](/molmil-images/mine/2b3y) | Structure of a monoclinic crystal form of human cytosolic aconitase (IRP1) | Descriptor: | ACETATE ION, FORMIC ACID, GLYCEROL, ... | Authors: | Dupuy, J, Fontecilla-Camps, J.C, Volbeda, A. | Deposit date: | 2005-09-22 | Release date: | 2006-01-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of human iron regulatory protein 1 as cytosolic aconitase Structure, 14, 2006
|
|