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7D9Y
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BU of 7d9y by Molmil
DNA binding domain of human DNA Ligase IV mutant - A3V
Descriptor: DNA ligase 4
Authors:Maddi, E.R, Raghavan, S.C, Natesh, R.
Deposit date:2020-10-14
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability.
Protein Eng.Des.Sel., 34, 2021
7DS4
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BU of 7ds4 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail F323K mutant
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-1
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7D8H
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BU of 7d8h by Molmil
CRTC1 pSer64 peptide in complex with 14-3-3 zeta
Descriptor: 14-3-3 protein zeta/delta, CRTC1 pSer64 peptide
Authors:Chen, H, Zhang, H, Xiang, S.
Deposit date:2020-10-08
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Insights into the Interaction Between CRTCs and 14-3-3.
J.Mol.Biol., 433, 2021
7DS3
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BU of 7ds3 by Molmil
Crystal structure of actin capping protein in complex with twinflin-2 C-terminus tail
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-2
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS6
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BU of 7ds6 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1/CD2AP CPI chimera peptide (TWN-CDC)
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-1,CD2-associated protein
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
1W9A
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BU of 1w9a by Molmil
Crystal structure of Rv1155 from Mycobacterium tuberculosis
Descriptor: PUTATIVE PYRIDOXINE/PYRIDOXAMINE 5'-PHOSPHATE OXIDASE
Authors:Cannan, S, Sulzenbacher, G, Roig-Zamboni, V, Scappuccini, L, Frassinetti, F, Maurien, D, Cambillau, C, Bourne, Y.
Deposit date:2004-10-07
Release date:2005-01-06
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Conserved Hypothetical Protein Rv1155 from Mycobacterium Tuberculosis
FEBS Lett., 579, 2005
7DSB
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BU of 7dsb by Molmil
Crystal structure of actin capping protein in complex with V-1 and twinfilin C-terminal tail
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Myotrophin, ...
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DQ6
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BU of 7dq6 by Molmil
Crystal structure of HitB in complex with (S)-beta-3-Br-phenylalanine sulfamoyladenosine
Descriptor: CALCIUM ION, Putative ATP-dependent b-aminoacyl-ACP synthetase, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl N-[(3S)-3-azanyl-3-(3-bromophenyl)propanoyl]sulfamate
Authors:Kudo, F, Takahashi, S, Miyanaga, A, Nakazawa, Y, Eguchi, T.
Deposit date:2020-12-22
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mutational Biosynthesis of Hitachimycin Analogs Controlled by the beta-Amino Acid-Selective Adenylation Enzyme HitB.
Acs Chem.Biol., 16, 2021
7DQ5
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BU of 7dq5 by Molmil
Crystal structure of HitB in complex with (S)-beta-phenylalanine sulfamoyladenosine
Descriptor: CALCIUM ION, Putative ATP-dependent b-aminoacyl-ACP synthetase, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(3~{S})-3-azanyl-3-phenyl-propanoyl]sulfamate
Authors:Kudo, F, Takahashi, S, Miyanaga, A, Nakazawa, Y, Eguchi, T.
Deposit date:2020-12-22
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Mutational Biosynthesis of Hitachimycin Analogs Controlled by the beta-Amino Acid-Selective Adenylation Enzyme HitB.
Acs Chem.Biol., 16, 2021
6R87
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BU of 6r87 by Molmil
Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state without Arb1)
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R.
Deposit date:2019-03-31
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
7D3A
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BU of 7d3a by Molmil
flavone reductase
Descriptor: 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Cd1, FLAVIN MONONUCLEOTIDE
Authors:Hong, S, Yang, G.H, Zhang, P.
Deposit date:2020-09-18
Release date:2021-03-03
Last modified:2021-09-29
Method:X-RAY DIFFRACTION (2.552 Å)
Cite:Discovery of an ene-reductase for initiating flavone and flavonol catabolism in gut bacteria.
Nat Commun, 12, 2021
6RAK
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BU of 6rak by Molmil
Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing occluded conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
4P6H
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BU of 4p6h by Molmil
Tl+-bound inward-facing state (bound conformation) of the glutamate transporter homologue GltPh
Descriptor: GltPh, MERCURY (II) ION, THALLIUM (I) ION
Authors:Verdon, G, Boudker, O.
Deposit date:2014-03-24
Release date:2014-06-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.08 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
7DHP
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BU of 7dhp by Molmil
Crystal structure of MazF from Deinococcus radiodurans
Descriptor: Endoribonuclease MazF, SULFATE ION
Authors:Zhao, Y, Dai, J.
Deposit date:2020-11-17
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:MazEF Toxin-Antitoxin System-Mediated DNA Damage Stress Response in Deinococcus radiodurans.
Front Genet, 12, 2021
4GMT
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BU of 4gmt by Molmil
Crystal structure of heterosubtypic Fab S139/1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ...
Authors:Lee, P.S, Ekiert, D.C, Wilson, I.A.
Deposit date:2012-08-16
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
Proc.Natl.Acad.Sci.USA, 109, 2012
3LRC
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BU of 3lrc by Molmil
Structure of E. coli AdiC (P1)
Descriptor: Arginine/agmatine antiporter
Authors:Gao, X, Lu, F, Zhou, L, Shi, Y.
Deposit date:2010-02-11
Release date:2010-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (4.004 Å)
Cite:Structure and mechanism of an amino acid antiporter
Science, 324, 2009
7NBX
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BU of 7nbx by Molmil
Lateral-open conformation of the lid-locked BAM complex (BamA E435C S665C, BamBDCE) by cryoEM
Descriptor: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
Authors:Haysom, S.F.
Deposit date:2021-01-28
Release date:2021-06-02
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding.
Nat Commun, 12, 2021
6R9Z
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BU of 6r9z by Molmil
3D NMR solution structure of ligand peptide (Ac)EVNPPVP of Pro-Pro endopeptidase-1
Descriptor: ACE-GLU-VAL-ASN-PRO-PRO-VAL-PRO-NH2
Authors:Diaz, D.
Deposit date:2019-04-04
Release date:2019-06-19
Last modified:2019-08-07
Method:SOLUTION NMR
Cite:Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1.
J.Biol.Chem., 294, 2019
7DAF
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BU of 7daf by Molmil
IXA in complex with tubulin
Descriptor: (1~{S},3~{S},7~{S},10~{R},11~{S},12~{S},16~{R})-8,8,10,12,16-pentamethyl-3-[(~{E})-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-7,11-bis(oxidanyl)-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Wu, C, Wang, Y.
Deposit date:2020-10-16
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design.
Biochem.Biophys.Res.Commun., 534, 2021
7NP7
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BU of 7np7 by Molmil
Structure of an intact ESX-5 inner membrane complex, Composite C1 model
Descriptor: ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5, ...
Authors:Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C.
Deposit date:2021-02-26
Release date:2021-06-02
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:Structure and dynamics of a mycobacterial type VII secretion system.
Nature, 593, 2021
7DAD
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BU of 7dad by Molmil
EPD in complex with tubulin
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Wang, Y, Wu, C.
Deposit date:2020-10-16
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design.
Biochem.Biophys.Res.Commun., 534, 2021
7DCD
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BU of 7dcd by Molmil
Nonstructural protein 7 and 8 complex of SARS-CoV-2
Descriptor: Non-structural protein 7, Non-structural protein 8
Authors:Zhang, C.H, Li, L, Su, D.
Deposit date:2020-10-24
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Nonstructural protein 7 and 8 complexes of SARS-CoV-2.
Protein Sci., 30, 2021
7DAE
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BU of 7dae by Molmil
EPB in complex with tubulin
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE, CALCIUM ION, ...
Authors:Wu, C, Wang, Y.
Deposit date:2020-10-16
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design.
Biochem.Biophys.Res.Commun., 534, 2021
6RAI
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BU of 6rai by Molmil
Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing occluded conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
4GG8
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BU of 4gg8 by Molmil
Immune Receptor
Descriptor: T-CELL RECEPTOR, SP3.4 ALPHA CHAIN, SP3.4 BETA CHAIN, ...
Authors:Broughton, S.E, Theodossis, A, Petersen, J, Reid, H.H, Rossjohn, J.
Deposit date:2012-08-06
Release date:2012-10-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.
Immunity, 37, 2012

222624

數據於2024-07-17公開中

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