4O6Z
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![BU of 4o6z by Molmil](/molmil-images/mine/4o6z) | Crystal structure of serine hydroxymethyltransferase with covalently bound PLP Schiff-base from Plasmodium falciparum | Descriptor: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase | Authors: | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U. | Deposit date: | 2013-12-24 | Release date: | 2014-06-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | The structure of Plasmodium falciparum serine hydroxymethyltransferase reveals a novel redox switch that regulates its activities. Acta Crystallogr.,Sect.D, 70, 2014
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4YTP
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![BU of 4ytp by Molmil](/molmil-images/mine/4ytp) | CRYSTAL STRUCTURE OF PORCINE HEART MITOCHONDRIAL COMPLEX II BOUND WITH N-[(4-tert-butylphenyl)methyl]-2-(trifluoromethyl)benzamide | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K. | Deposit date: | 2015-03-18 | Release date: | 2015-08-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
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4OHX
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![BU of 4ohx by Molmil](/molmil-images/mine/4ohx) | C. Elegans Clp1 bound to ADP and Mg2+ (RNA released state) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | Deposit date: | 2014-01-18 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1. Mol.Cell, 54, 2014
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4YVN
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![BU of 4yvn by Molmil](/molmil-images/mine/4yvn) | Crystal structure of CotA laccase complexed with ABTS at a novel binding site | Descriptor: | 1,2-ETHANEDIOL, 3-ETHYL-2-[(2Z)-2-(3-ETHYL-6-SULFO-1,3-BENZOTHIAZOL-2(3H)-YLIDENE)HYDRAZINO]-6-SULFO-3H-1,3-BENZOTHIAZOL-1-IUM, COPPER (II) ION, ... | Authors: | Liu, Z.C, Xie, T, Wang, G.G. | Deposit date: | 2015-03-20 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of CotA laccase complexed with 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) at a novel binding site Acta Crystallogr.,Sect.F, 72, 2016
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4YUB
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4OK1
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![BU of 4ok1 by Molmil](/molmil-images/mine/4ok1) | Crystal structure of W741L-AR-LBD bound with co-regulator peptide | Descriptor: | Androgen receptor, R-BICALUTAMIDE, co-regulator peptide | Authors: | Liu, J.S, Hsu, C.L, Wu, W.G. | Deposit date: | 2014-01-21 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
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4YL0
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![BU of 4yl0 by Molmil](/molmil-images/mine/4yl0) | Crystal Structures of mPGES-1 Inhibitor Complexes | Descriptor: | 2-(9-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)benzene-1,3-dicarbonitrile, DI(HYDROXYETHYL)ETHER, GLUTATHIONE, ... | Authors: | Luz, J.G, Antonysamy, S, Kuklish, S.L, Fisher, M.J. | Deposit date: | 2015-03-04 | Release date: | 2015-06-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics. J.Med.Chem., 58, 2015
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4OKH
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![BU of 4okh by Molmil](/molmil-images/mine/4okh) | Crystal structure of calpain-3 penta-EF-hand domain | Descriptor: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, CALCIUM ION, Calpain-3 | Authors: | Karunan Partha, S, Ravulapalli, R, Campbell, R.L, Allingham, J.S, Davies, P.L. | Deposit date: | 2014-01-22 | Release date: | 2014-05-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of calpain-3 penta-EF-hand (PEF) domain - a homodimerized PEF family member with calcium bound at the fifth EF-hand. Febs J., 281, 2014
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4OKY
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![BU of 4oky by Molmil](/molmil-images/mine/4oky) | Crystal structure of PvuRts1I, a 5-hydroxymethylcytosine DNA restriction endonuclease | Descriptor: | Restriction endonuclease PvuRts1 I | Authors: | Wang, C.L, Shao, C, Zang, J.Y. | Deposit date: | 2014-01-23 | Release date: | 2014-09-10 | Last modified: | 2014-12-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for the substrate selectivity of PvuRts1I, a 5-hydroxymethylcytosine DNA restriction endonuclease Acta Crystallogr.,Sect.D, 70, 2014
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4YV1
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4OL7
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![BU of 4ol7 by Molmil](/molmil-images/mine/4ol7) | |
4YM2
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4YVP
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![BU of 4yvp by Molmil](/molmil-images/mine/4yvp) | Crystal Structure of AKR1C1 complexed with glibenclamide | Descriptor: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhao, Y, Zheng, X, Zhang, H, Hu, X. | Deposit date: | 2015-03-20 | Release date: | 2015-11-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis Chem.Biol.Interact., 240, 2015
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4OM4
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![BU of 4om4 by Molmil](/molmil-images/mine/4om4) | Crystal structure of CTX A2 from Taiwan Cobra (Naja naja atra) | Descriptor: | Cytotoxin 2 | Authors: | Lin, C.C, Chang, C.I, Wu, W.G. | Deposit date: | 2014-01-26 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface. J.Biol.Chem., 289, 2014
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4OM8
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![BU of 4om8 by Molmil](/molmil-images/mine/4om8) | Crystal structure of 5-formly-3-hydroxy-2-methylpyridine 4-carboxylic acid (FHMPC) 5-dehydrogenase, an NAD+ dependent dismutase. | Descriptor: | 3-hydroxybutyryl-coA dehydrogenase, ACETATE ION, BETA-MERCAPTOETHANOL, ... | Authors: | Mugo, A.N, Kobayashi, J, Mikami, B, Yagi, T, Ohnishi, K. | Deposit date: | 2014-01-27 | Release date: | 2015-01-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD(+)-dependent dismutase from Mesorhizobium loti Biochem.Biophys.Res.Commun., 456, 2015
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4OBF
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4OBS
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![BU of 4obs by Molmil](/molmil-images/mine/4obs) | Crystal structure of human alpha-L-iduronidase in the P212121 form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, CHLORIDE ION, ... | Authors: | Bie, H, Yin, J, He, X, Kermode, A.R, James, M.N.G. | Deposit date: | 2014-01-07 | Release date: | 2015-01-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal structure of human alpha-L-iduronidase in the P212121 form To be Published
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4OMX
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![BU of 4omx by Molmil](/molmil-images/mine/4omx) | Crystal structure of goat beta-lactoglobulin (trigonal form) | Descriptor: | FORMAMIDE, SULFATE ION, UREA, ... | Authors: | Loch, J.I, Swiatek, S, Czub, M, Ludwikowska, M, Lewinski, K. | Deposit date: | 2014-01-27 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformational variability of goat beta-lactoglobulin: Crystallographic and thermodynamic studies. Int.J.Biol.Macromol., 72C, 2014
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4ON3
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![BU of 4on3 by Molmil](/molmil-images/mine/4on3) | Crystal structure of human sorting nexin 10 (SNX10) | Descriptor: | NITRATE ION, PENTAETHYLENE GLYCOL, SODIUM ION, ... | Authors: | Xu, T, Xu, J, Wang, Q, Liu, J. | Deposit date: | 2014-01-28 | Release date: | 2014-09-24 | Last modified: | 2014-12-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis. Proteins, 82, 2014
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4YAX
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![BU of 4yax by Molmil](/molmil-images/mine/4yax) | Crystal structure of TRIM24 PHD-bromodomain complexed with N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzenesulfonamide (5g) | Descriptor: | GLYCEROL, N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl]benzenesulfonamide, SULFATE ION, ... | Authors: | Poncet-Montange, G, Palmer, W, Jones, P. | Deposit date: | 2015-02-18 | Release date: | 2015-06-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor. J.Med.Chem., 59, 2016
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4OCO
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![BU of 4oco by Molmil](/molmil-images/mine/4oco) | N-acetylhexosamine 1-phosphate kinase in complex with GlcNAc-1-phosphate | Descriptor: | 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, N-acetylhexosamine 1-phosphate kinase | Authors: | Li, T.L, Wang, K.C, Lyu, S.Y, Liu, Y.C, Chang, C.Y, Wu, C.J. | Deposit date: | 2014-01-09 | Release date: | 2014-05-14 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes. Acta Crystallogr.,Sect.D, 70, 2014
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4YP6
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![BU of 4yp6 by Molmil](/molmil-images/mine/4yp6) | Crystal structure of Methanobacterium thermoautotrophicum NMNAT in complex with NADP | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Nicotinamide-nucleotide adenylyltransferase | Authors: | Pfoh, R, Christendat, D, Pai, E.F, Saridakis, V. | Deposit date: | 2015-03-12 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Nicotinamide mononucleotide adenylyltransferase displays alternate binding modes for nicotinamide nucleotides. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4YPJ
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![BU of 4ypj by Molmil](/molmil-images/mine/4ypj) | X-ray Structure of The Mutant of Glycoside Hydrolase | Descriptor: | Beta galactosidase | Authors: | Ishikawa, K, Kataoka, M, Yanamoto, T, Nakabayashi, M, Watanabe, M. | Deposit date: | 2015-03-13 | Release date: | 2015-04-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of beta-galactosidase from Bacillus circulans ATCC 31382 (BgaD) and the construction of the thermophilic mutants. Febs J., 282, 2015
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4OO4
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4YB4
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![BU of 4yb4 by Molmil](/molmil-images/mine/4yb4) | Crystal structure of homoisocitrate dehydrogenase from Thermus thermophilus in complex with homoisocitrate, magnesium ion (II) and NADH | Descriptor: | (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylic acid, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Takahashi, K, Tomita, T, Kuzuyama, T, Nishiyama, M. | Deposit date: | 2015-02-18 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of homoisocitrate dehydrogenase from Thermus thermophilus in complex with homoisocitrate, magnesium(II) and NADH To Be Published
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