3VQJ
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![BU of 3vqj by Molmil](/molmil-images/mine/3vqj) | Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase | Descriptor: | Carbonyl sulfide hydrolase, SODIUM ION, ZINC ION | Authors: | Katayama, Y, Noguchi, K, Ogawa, T, Ohtaki, A, Odaka, M, Yohda, M. | Deposit date: | 2012-03-24 | Release date: | 2013-02-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the beta-Carbonic Anhydrase Family Enzymes J.Am.Chem.Soc., 135, 2013
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3VRK
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![BU of 3vrk by Molmil](/molmil-images/mine/3vrk) | Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase / Thiocyanate complex | Descriptor: | Carbonyl sulfide hydrolase, SODIUM ION, THIOCYANATE ION, ... | Authors: | Katayama, Y, Noguchi, K, Ogawa, T, Ohtaki, A, Odaka, M, Yohda, M. | Deposit date: | 2012-04-11 | Release date: | 2013-02-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the beta-Carbonic Anhydrase Family Enzymes J.Am.Chem.Soc., 135, 2013
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7C95
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![BU of 7c95 by Molmil](/molmil-images/mine/7c95) | Crystal structure of the anti-human podoplanin antibody Fab fragment | Descriptor: | GLYCEROL, Heavy chain of Fab fragment, Light chain of Fab fragment, ... | Authors: | Nakamura, S, Suzuki, K, Ogasawara, S, Naruchi, K, Shimabukuro, J, Tukahara, N, Kaneko, M.K, Kato, Y, Murata, T. | Deposit date: | 2020-06-04 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal structure of an anti-podoplanin antibody bound to a disialylated O-linked glycopeptide. Biochem.Biophys.Res.Commun., 533, 2020
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7C94
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![BU of 7c94 by Molmil](/molmil-images/mine/7c94) | Crystal structure of the anti-human podoplanin antibody Fab fragment complex with glycopeptide | Descriptor: | GLYCEROL, Heavy chain of Fab fragment, Light chain of Fab fragment, ... | Authors: | Suzuki, K, Nakamura, S, Ogasawara, S, Naruchi, K, Shimabukuro, J, Tukahara, N, Kaneko, M.K, Kato, Y, Murata, T. | Deposit date: | 2020-06-04 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Crystal structure of an anti-podoplanin antibody bound to a disialylated O-linked glycopeptide. Biochem.Biophys.Res.Commun., 533, 2020
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7FAL
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![BU of 7fal by Molmil](/molmil-images/mine/7fal) | Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with T36 and L-pro | Descriptor: | 4-[(3R)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, PROLINE, Prolyl-tRNA synthetase (ProRS) | Authors: | Malhotra, N, Mishra, S, Yogavel, M, Sharma, A. | Deposit date: | 2021-07-06 | Release date: | 2022-08-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.219 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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7FAN
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![BU of 7fan by Molmil](/molmil-images/mine/7fan) | Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with T35 and L-pro | Descriptor: | 4-[(3S)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, PROLINE, Prolyl-tRNA synthetase (ProRS) | Authors: | Mishra, S, Malhotra, N, Yogavel, M, Sharma, A. | Deposit date: | 2021-07-06 | Release date: | 2022-09-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.769 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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7FAM
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![BU of 7fam by Molmil](/molmil-images/mine/7fam) | Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with L97 and L-pro | Descriptor: | 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, PROLINE, Prolyl-tRNA synthetase (ProRS) | Authors: | Mishra, S, Malhotra, N, Yogavel, M, Sharma, A. | Deposit date: | 2021-07-06 | Release date: | 2022-09-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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7FAK
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![BU of 7fak by Molmil](/molmil-images/mine/7fak) | Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with L96 and L-pro | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[(3S)-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(5-methoxypyridin-3-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, ACETATE ION, ... | Authors: | Malhotra, N, Mishra, S, Yogavel, M, Sharma, A. | Deposit date: | 2021-07-06 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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2K85
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![BU of 2k85 by Molmil](/molmil-images/mine/2k85) | p190-A RhoGAP FF1 domain | Descriptor: | Glucocorticoid receptor DNA-binding factor 1 | Authors: | Bonet, R, Ruiz, L, Martin-Malpartida, P, Macias, M. | Deposit date: | 2008-09-02 | Release date: | 2009-05-19 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR structural studies on human p190-A RhoGAPFF1 revealed that domain phosphorylation by the PDGF-receptor alpha requires its previous unfolding. J.Mol.Biol., 389, 2009
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2LRQ
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![BU of 2lrq by Molmil](/molmil-images/mine/2lrq) | Chemical Shift Assignment and Solution Structure of Fr822A from Drosophila melanogaster. Northeast Structural Genomics Consortium Target Fr822A | Descriptor: | NuA4 complex subunit EAF3 homolog | Authors: | Lee, H, Lee, D, Kohan, E, Janjua, H, Xiao, R, Acton, T, Everett, J.K, Montelione, G, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) | Deposit date: | 2012-04-11 | Release date: | 2012-07-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of Fr822A from Drosophila melanogaster. To be Published
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2KL8
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![BU of 2kl8 by Molmil](/molmil-images/mine/2kl8) | Solution NMR Structure of de novo designed ferredoxin-like fold protein, Northeast Structural Genomics Consortium Target OR15 | Descriptor: | OR15 | Authors: | Liu, G, Koga, N, Jiang, M, Koga, R, Xiao, R, Ciccosanti, C, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-30 | Release date: | 2009-07-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Principles for designing ideal protein structures. Nature, 491, 2012
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2LN3
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![BU of 2ln3 by Molmil](/molmil-images/mine/2ln3) | Solution NMR Structure of DE NOVO DESIGNED PROTEIN, IF3-like fold, Northeast Structural Genomics Consortium Target OR135 (CASD target) | Descriptor: | DE NOVO DESIGNED PROTEIN OR135 | Authors: | Liu, G, Koga, R, Koga, N, Xiao, R, Lee, H, Janjua, H, Kohan, E, Acton, T.B, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-12-15 | Release date: | 2012-02-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Principles for designing ideal protein structures. Nature, 491, 2012
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2LTA
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![BU of 2lta by Molmil](/molmil-images/mine/2lta) | Solution NMR structure of De novo designed protein, rossmann 3x1 fold, Northeast Structural Genomics Consortium target OR157 | Descriptor: | De novo designed protein | Authors: | Liu, G, Koga, R, Koga, N, Xiao, R, Pederson, K, Hamilton, K, Kohan, E, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-15 | Release date: | 2012-06-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Principles for designing ideal protein structures. Nature, 491, 2012
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2LAQ
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![BU of 2laq by Molmil](/molmil-images/mine/2laq) | |
1JND
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![BU of 1jnd by Molmil](/molmil-images/mine/1jnd) | Crystal structure of imaginal disc growth factor-2 | Descriptor: | Imaginal disc growth factor-2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Varela, P.F, Llera, A.S, Mariuzza, R.A, Tormo, J. | Deposit date: | 2001-07-23 | Release date: | 2002-05-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster. J.Biol.Chem., 277, 2002
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1JNE
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![BU of 1jne by Molmil](/molmil-images/mine/1jne) | Crystal structure of imaginal disc growth factor-2 | Descriptor: | Imaginal disc growth factor-2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Varela, P.F, Llera, A.S, Mariuzza, R.A, Tormo, J. | Deposit date: | 2001-07-23 | Release date: | 2002-05-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster. J.Biol.Chem., 277, 2002
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2KJR
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![BU of 2kjr by Molmil](/molmil-images/mine/2kjr) | Solution NMR structure of the N-terminal Ubiquitin-like Domain from Tubulin-binding Cofactor B, CG11242, from Drosophila melanogaster. Northeast Structural Genomics Consortium Target FR629A (residues 8-92) | Descriptor: | CG11242 | Authors: | Ramelot, T.A, Cort, J.R, Shastry, R, Ciccosanti, C, Jiang, M, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-08 | Release date: | 2009-06-23 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the N-terminal Ubiquitin-like Domain from
Tubulin-binding Cofactor B, CG11242, from Drosophila melanogaster. Northeast
Structural Genomics Consortium Target FR629A (residues 8-92) To be Published
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4BM8
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![BU of 4bm8 by Molmil](/molmil-images/mine/4bm8) | Galectin-3c in complex with Bisamido-thiogalactoside derivate 3 | Descriptor: | (3-Deoxy-3-(2,3,5,6-tetra-fluoro-4-methoxy-benzamido)-b-D-galactopyranosyl)-(3-deoxy-3-(2,3,5,6-tetra-fluoro-4-methoxy-benzamido)-2-O-sulfo-b-D-galactopyranosyl)-sulfide, GALECTIN-3 | Authors: | Noresson, A.L, Oberg, C.T, Engstrom, O, Hakansson, M, Logan, D.T, Leffler, H, Nilsson, U.J. | Deposit date: | 2013-05-07 | Release date: | 2014-05-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (0.96 Å) | Cite: | Controlling Protein Conformation Through Electronic Fine-Tuning of Arginine-Arene Interactions: Synthetic, Structural, and Biological Studies To be Published
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1OOF
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![BU of 1oof by Molmil](/molmil-images/mine/1oof) | Complex of Drosophila odorant binding protein LUSH with ethanol | Descriptor: | ACETATE ION, ETHANOL, odorant binding protein LUSH | Authors: | Kruse, S.W, Zhao, R, Smith, D.P, Jones, D.N.M. | Deposit date: | 2003-03-03 | Release date: | 2003-09-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol., 10, 2003
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1OOG
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![BU of 1oog by Molmil](/molmil-images/mine/1oog) | Complex of Drosophila odorant binding protein LUSH with propanol | Descriptor: | ACETATE ION, N-PROPANOL, odorant binding protein LUSH | Authors: | Kruse, S.W, Zhao, R, Smith, D.P, Jones, D.N.M. | Deposit date: | 2003-03-03 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol., 10, 2003
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4BLJ
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![BU of 4blj by Molmil](/molmil-images/mine/4blj) | Galectin-3c in complex with Bisamido-thiogalactoside derivate 2 | Descriptor: | Bis-(3-deoxy-3-(3-methoxy-benzamido)-b-D-galactopyranosyl)-sulfide, GALECTIN-3 | Authors: | Noresson, A.L, Oberg, C.T, Engstrom, O, Hakansson, M, Logan, D.T, Leffler, H, Nilsson, U.J. | Deposit date: | 2013-05-03 | Release date: | 2014-05-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Controlling Protein Conformation Through Electronic Fine-Tuning of Arginine-Arene Interactions: Synthetic, Structural, and Biological Studies To be Published
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1OOH
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![BU of 1ooh by Molmil](/molmil-images/mine/1ooh) | Complex of Drosophila odorant binding protein LUSH with butanol | Descriptor: | 1-BUTANOL, ACETATE ION, odorant binding protein LUSH | Authors: | Kruse, S.W, Zhao, R, Smith, D.P, Jones, D.N.M. | Deposit date: | 2003-03-03 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol., 10, 2003
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2D8L
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![BU of 2d8l by Molmil](/molmil-images/mine/2d8l) | Crystal Structure of Unsaturated Rhamnogalacturonyl Hydrolase in complex with dGlcA-GalNAc | Descriptor: | 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, Putative glycosyl hydrolase yteR | Authors: | Itoh, T, Ochiai, A, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2005-12-06 | Release date: | 2006-11-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A novel glycoside hydrolase family 105: the structure of family 105 unsaturated rhamnogalacturonyl hydrolase complexed with a disaccharide in comparison with family 88 enzyme complexed with the disaccharide J.Mol.Biol., 360, 2006
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2K1F
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![BU of 2k1f by Molmil](/molmil-images/mine/2k1f) | SUMO-3 from Drosophila melanogaster (dsmt3) | Descriptor: | CG4494-PA | Authors: | Kumar, D, Misra, J.R, Misra, A.K, Chugh, J, Sharma, S, Hosur, R.V. | Deposit date: | 2008-03-03 | Release date: | 2009-03-10 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR-derived solution structure of SUMO from Drosophila melanogaster (dSmt3). Proteins, 75, 2009
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5ODY
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![BU of 5ody by Molmil](/molmil-images/mine/5ody) | Galectin-3C in complex with dithiogalactoside derivative | Descriptor: | 5,6-bis(fluoranyl)-3-[[(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxan-2-yl]sulfanyl-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]chromen-2-one, Galectin-3 | Authors: | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | Deposit date: | 2017-07-07 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.149 Å) | Cite: | Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity. J. Med. Chem., 61, 2018
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