5OMQ
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![BU of 5omq by Molmil](/molmil-images/mine/5omq) | Ternary complex of 9N DNA polymerase in the replicative state with three metal ions in the active site | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA Primer, DNA Template, ... | Authors: | Betz, K, Marx, A, Diederichs, K. | Deposit date: | 2017-08-01 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
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5VU9
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![BU of 5vu9 by Molmil](/molmil-images/mine/5vu9) | TNA polymerase, translocated product | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU8
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![BU of 5vu8 by Molmil](/molmil-images/mine/5vu8) | TNA polymerase, closed ternary complex | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU6
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![BU of 5vu6 by Molmil](/molmil-images/mine/5vu6) | |
5VU5
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![BU of 5vu5 by Molmil](/molmil-images/mine/5vu5) | TNA polymerase, apo | Descriptor: | DNA polymerase | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU7
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![BU of 5vu7 by Molmil](/molmil-images/mine/5vu7) | TNA polymerase, open ternary complex | Descriptor: | 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5N2E
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![BU of 5n2e by Molmil](/molmil-images/mine/5n2e) | Structure of the E9 DNA polymerase from vaccinia virus | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | Deposit date: | 2017-02-07 | Release date: | 2017-11-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8, 2017
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5N2H
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![BU of 5n2h by Molmil](/molmil-images/mine/5n2h) | Structure of the E9 DNA polymerase exonuclease deficient mutant (D166A+E168A) from vaccinia virus | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | Deposit date: | 2017-02-07 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8, 2017
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5N2G
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![BU of 5n2g by Molmil](/molmil-images/mine/5n2g) | Structure of the E9 DNA polymerase from vaccinia virus in complex with manganese | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | Deposit date: | 2017-02-07 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8, 2017
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5H12
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![BU of 5h12 by Molmil](/molmil-images/mine/5h12) | |
5MDN
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![BU of 5mdn by Molmil](/molmil-images/mine/5mdn) | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis | Descriptor: | DNA polymerase, MAGNESIUM ION | Authors: | Guo, J, Zhang, W, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Akhtar, M. | Deposit date: | 2016-11-12 | Release date: | 2016-12-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis. Acta Crystallogr D Struct Biol, 73, 2017
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5IUD
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5EXR
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![BU of 5exr by Molmil](/molmil-images/mine/5exr) | Crystal structure of human primosome | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | Authors: | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | Deposit date: | 2015-11-24 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
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4Q5V
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![BU of 4q5v by Molmil](/molmil-images/mine/4q5v) | Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and aphidicolin | Descriptor: | (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthale ne-3,9-diol, DNA polymerase alpha catalytic subunit, DNA template, ... | Authors: | Baranovskiy, A.G, Babayeva, N.D, Suwa, Y, Gu, J, Tahirov, T.H. | Deposit date: | 2014-04-17 | Release date: | 2014-11-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural basis for inhibition of DNA replication by aphidicolin. Nucleic Acids Res., 42, 2014
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4QCL
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![BU of 4qcl by Molmil](/molmil-images/mine/4qcl) | Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and dCTP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA TEMPLATE, ... | Authors: | Baranovskiy, A.G, Suwa, Y, Babayeva, N.D, Gu, J, Tahirov, T.H. | Deposit date: | 2014-05-12 | Release date: | 2014-11-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Activity and fidelity of human DNA polymerase alpha depend on primer structure J.Biol.Chem., 2018
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4J2B
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![BU of 4j2b by Molmil](/molmil-images/mine/4j2b) | RB69 DNA Polymerase L415G Ternary Complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*T)-3'), ... | Authors: | Xia, S, Wang, J, Konigsberg, W.H. | Deposit date: | 2013-02-04 | Release date: | 2014-02-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res., 41, 2013
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4J2D
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![BU of 4j2d by Molmil](/molmil-images/mine/4j2d) | RB69 DNA Polymerase L415K Ternary Complex | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | Authors: | Xia, S, Wang, J, Konigsberg, W.H. | Deposit date: | 2013-02-04 | Release date: | 2014-02-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Role of L415 in the Replication of RB69 DNA Polymerase To be Published
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4J2E
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![BU of 4j2e by Molmil](/molmil-images/mine/4j2e) | RB69 DNA Polymerase L415M Ternary Complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*G)-3'), ... | Authors: | Xia, S, Wang, J, Konigsberg, W.H. | Deposit date: | 2013-02-04 | Release date: | 2014-02-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res., 41, 2013
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4J2A
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![BU of 4j2a by Molmil](/molmil-images/mine/4j2a) | RB69 DNA Polymerase L415A Ternary Complex | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | Authors: | Xia, S, Wang, J, Konigsberg, W.H. | Deposit date: | 2013-02-04 | Release date: | 2014-02-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res., 41, 2013
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4M41
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4M3Z
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![BU of 4m3z by Molmil](/molmil-images/mine/4m3z) | |
4M3Y
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![BU of 4m3y by Molmil](/molmil-images/mine/4m3y) | |
4M3X
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4M42
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4M3R
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![BU of 4m3r by Molmil](/molmil-images/mine/4m3r) | |