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7YTY
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BU of 7yty by Molmil
Mouse SVCT1 in an apo state
Descriptor: Solute carrier family 23 member 1
Authors:She, J, Wang, M, He, J, Zhang, K, Li, S.
Deposit date:2022-08-16
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter.
Nat Commun, 14, 2023
6E1K
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BU of 6e1k by Molmil
Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab
Descriptor: CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ...
Authors:Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
Deposit date:2018-07-10
Release date:2018-09-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7YPV
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BU of 7ypv by Molmil
Crystal structure of OrE-ST-F
Descriptor: Acetyltransferase, Streptothricin F
Authors:Wang, Y.L, Li, T.L.
Deposit date:2022-08-04
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.415 Å)
Cite:N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023
7YRK
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BU of 7yrk by Molmil
Crystal structure of the hen egg lysozyme-2-oxidobenzylidene-threoninato-copper (II) complex
Descriptor: (6~{S})-6-[(1~{R})-1-oxidanylethyl]-2,4-dioxa-7$l^{4}-aza-3$l^{3}-cupratricyclo[7.4.0.0^{3,7}]trideca-1(13),7,9,11-tetraen-5-one, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Unno, M, Furuya, T, Kitanishi, K, Akitsu, T.
Deposit date:2022-08-10
Release date:2023-05-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:A novel hybrid protein composed of superoxide-dismutase-active Cu(II) complex and lysozyme.
Sci Rep, 13, 2023
7YX0
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BU of 7yx0 by Molmil
Crystal structure of the full-length short LOV protein SBW25-LOV from Pseudomonas fluorescens (light state)
Descriptor: ACETATE ION, FLAVIN MONONUCLEOTIDE, Flavin mononucleotide (semi-quinone intermediate), ...
Authors:Arinkin, V, Batra-Safferling, R, Granzin, J.
Deposit date:2022-02-15
Release date:2023-05-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conserved Signal Transduction Mechanisms and Dark Recovery Kinetic Tuning in the Pseudomonadaceae Short Light, Oxygen, Voltage (LOV) Protein Family.
J.Mol.Biol., 2024
7YVR
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BU of 7yvr by Molmil
Crystal Structure of L-Threonine Aldolase from Neptunomonas marina
Descriptor: GLYCEROL, L-threonine aldolase
Authors:He, Y.Z, Wang, J, Yan, W.P, Zhang, Y, Feng, Y.
Deposit date:2022-08-19
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery and Engineering of the L-Threonine Aldolase from Neptunomonas marine for the Efficient Synthesis of beta-Hydroxy-alpha-amino Acids via C-C Formation
Acs Catalysis, 2023
7YNK
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BU of 7ynk by Molmil
Structure of human SGLT2-MAP17 complex in the apo state in the inward-facing conformation
Descriptor: PDZK1-interacting protein 1, Sodium/glucose cotransporter 2
Authors:Chen, L, Niu, Y.
Deposit date:2022-07-31
Release date:2023-05-31
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7YNI
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BU of 7yni by Molmil
Structure of human SGLT1-MAP17 complex bound with substrate 4D4FDG in the occluded conformation
Descriptor: (2R,3R,4R,5S,6R)-5-fluoranyl-6-(hydroxymethyl)oxane-2,3,4-triol, PDZK1-interacting protein 1, Sodium/glucose cotransporter 1
Authors:Chen, L, Niu, Y, Cui, W.
Deposit date:2022-07-31
Release date:2023-05-31
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7ZAX
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BU of 7zax by Molmil
Solution structure of thanatin-like derivative 7 in complex with K. pneumoniae LptA
Descriptor: Lipopolysaccharide export system protein LptA, Thanatin-like derivative
Authors:Oi, K.K, Moehle, K, Zerbe, O.
Deposit date:2022-03-22
Release date:2023-06-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Sci Adv, 9, 2023
7ZED
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BU of 7zed by Molmil
Solution structure of thanatin-like derivative 7 in complex with E.coli LptA mutant Q62L
Descriptor: Lipopolysaccharide export system protein LptA, Thanatin-like derivative
Authors:Moehle, K, Zerbe, O.
Deposit date:2022-03-31
Release date:2023-06-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Sci Adv, 9, 2023
7YWR
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BU of 7ywr by Molmil
NMR structure of the N-terminal domain of Nsp8 from SARS-CoV-2
Descriptor: ORF1a polyprotein
Authors:Mompean, M, Laurents, D.V, Pantoja-Uceda, D, Trevino, M.A.
Deposit date:2022-02-14
Release date:2022-03-02
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:NMR structure of the N-terminal domain of Nsp8 from SARS-CoV-2
To Be Published
7ZEY
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BU of 7zey by Molmil
Complex Cyp33-RRM : MLL1-PHD3
Descriptor: MLL cleavage product N320, Peptidyl-prolyl cis-trans isomerase E, ZINC ION
Authors:Blatter, M, Allain, F, Meylan, C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
7Z6I
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BU of 7z6i by Molmil
Crystal structure of p38alpha C162S in complex with SB20358 and CAS 2094667-81-7 (behind catalytic site; Y35 in), P 21 21 21
Descriptor: 4-[4-(4-fluorophenyl)-2-[4-[methyl(oxidanyl)-$l^{3}-sulfanyl]phenyl]-1~{H}-imidazol-5-yl]pyridine, Mitogen-activated protein kinase 14, N-(2-cyclobutyl-1H-1,3-benzodiazol-5-yl)benzenesulfonamide
Authors:Baginski, B, Pous, J, Gonzalez, L, Macias, M.J, Nebreda, A.R.
Deposit date:2022-03-11
Release date:2023-06-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Characterization of p38 alpha autophosphorylation inhibitors that target the non-canonical activation pathway.
Nat Commun, 14, 2023
7YRP
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BU of 7yrp by Molmil
Crystal structure of VIM-28 metallo-beta-lactamase
Descriptor: CITRATE ANION, GLYCEROL, Metallo-beta-lactamase VIM-28, ...
Authors:Shimizu-Ibuka, A, Sato, H.
Deposit date:2022-08-10
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of VIM-28 metallo-beta-lactamase
To Be Published
7Z9T
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BU of 7z9t by Molmil
Crystal structure of p38alpha C162S in complex with ATPgS and CAS 2094667-81-7 (in catalytic site, Y35 out), P 1 21 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Mitogen-activated protein kinase 14, N-(2-cyclobutyl-1H-1,3-benzodiazol-5-yl)benzenesulfonamide
Authors:Baginski, B, Pous, J, Gonzalez, L, Macias, M.J, Nebreda, A.R.
Deposit date:2022-03-21
Release date:2023-06-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Characterization of p38 alpha autophosphorylation inhibitors that target the non-canonical activation pathway.
Nat Commun, 14, 2023
7YRY
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BU of 7yry by Molmil
F1-ATPase of Acinetobacter baumannii
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
Authors:Saw, W.-G, Grueber, G.
Deposit date:2022-08-11
Release date:2023-06-21
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Atomic insights of an up and down conformation of the Acinetobacter baumannii F 1 -ATPase subunit epsilon and deciphering the residues critical for ATP hydrolysis inhibition and ATP synthesis.
Faseb J., 37, 2023
7ZC7
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BU of 7zc7 by Molmil
Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012941
Descriptor: 2-[4-(3,5-dimethylpyrazol-1-yl)phenyl]-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)ethanamide, N-glycosylase/DNA lyase, NICKEL (II) ION
Authors:Davies, J.R, Scaletti, E, Stenmark, P.
Deposit date:2022-03-25
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012941
To Be Published
3V9E
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BU of 3v9e by Molmil
Structure of the L499M mutant of the laccase from B.aclada
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, GLYCEROL, ...
Authors:Osipov, E.M, Polyakov, K.M, Tikhonova, T.V, Dorovatovsky, P.V, Ludwig, R, Kittl, R, Shleev, S.V, Popov, V.O.
Deposit date:2011-12-27
Release date:2013-01-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Effect of the L499M mutation of the ascomycetous Botrytis aclada laccase on redox potential and catalytic properties.
Acta Crystallogr.,Sect.D, 70, 2014
4ZT0
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BU of 4zt0 by Molmil
Crystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolution
Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA
Authors:Jiang, F, Doudna, J.A.
Deposit date:2015-05-14
Release date:2015-07-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
7YN3
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BU of 7yn3 by Molmil
Crystal structure of CcbD complex with CcbZ carrier protein domain
Descriptor: 1,1'-ethane-1,2-diyldipyrrolidine-2,5-dione, 4'-PHOSPHOPANTETHEINE, CcbD, ...
Authors:Mori, T, Lyu, S, Abe, I.
Deposit date:2022-07-29
Release date:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of CcbD complex with carrier protein
To Be Published
7YNQ
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BU of 7ynq by Molmil
PiB-bound alpha-synuclein fibrils conformation 2
Descriptor: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:PiB-bound alpha-synuclein fibrils conformation 2
To Be Published
4ZS7
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BU of 4zs7 by Molmil
Structural mimicry of receptor interaction by antagonistic IL-6 antibodies
Descriptor: Interleukin-6, Llama Fab fragment 68F2 heavy chain, Llama Fab fragment 68F2 light chain
Authors:Blanchetot, C, De Jonge, N, Desmyter, A, Ongenae, N, Hofman, E, Klarenbeek, A, Sadi, A, Hultberg, A, Kretz-Rommel, A, Spinelli, S, Loris, R, Cambillau, C, de Haard, H.
Deposit date:2015-05-13
Release date:2016-05-04
Last modified:2016-07-06
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.
J.Biol.Chem., 291, 2016
7YNT
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BU of 7ynt by Molmil
pFTAA-bound alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:pFTAA-bound alpha-synuclein fibrils
To Be Published
7YNM
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BU of 7ynm by Molmil
ThT-bound alpha-synuclein fibrils conformation 1
Descriptor: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-07-31
Release date:2023-08-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:ThT-bound alpha-synuclein fibrils conformation 1
To Be Published
7YOE
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BU of 7yoe by Molmil
Crystal Structure of A68P single mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae at 1.88 A
Descriptor: Cysteine synthase
Authors:Kumar, N, Rahisuddin, R, Saini, N, Singh, A.K.
Deposit date:2022-08-01
Release date:2023-08-02
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal Structure of A68P single mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae at 1.88 A
To Be Published

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數據於2024-07-17公開中

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