7ZAX

Solution structure of thanatin-like derivative 7 in complex with K. pneumoniae LptA

Summary for 7ZAX

• Entry DOI: 10.2210/pdb7zax/pdb
• NMR Information: BMRB: 34716
• Descriptor: Lipopolysaccharide export system protein LptA, Thanatin-like derivative (2 entities in total)
• Functional Keywords: structure from cyana 3.98.13, antibiotic
• Biological source: Klebsiella pneumoniae; More
• Total number of polymer chains: 2
• Total formula weight: 16797.97

Authors

Oi, K.K.,Moehle, K.,Zerbe, O. (deposition date: 2022-03-22, release date: 2023-06-07, Last modification date: 2023-11-15)

• Primary citation: Schuster, M.,Brabet, E.,Oi, K.K.,Desjonqueres, N.,Moehle, K.,Le Poupon, K.,Hell, S.,Gable, S.,Rithie, V.,Dillinger, S.,Zbinden, P.,Luther, A.,Li, C.,Stiegeler, S.,D'Arco, C.,Locher, H.,Remus, T.,DiMaio, S.,Motta, P.,Wach, A.,Jung, F.,Upert, G.,Obrecht, D.,Benghezal, M.,Zerbe, O.; Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.; Sci Adv, 9:eadg3683-eadg3683, 2023; PubMed: 37224246; DOI: 10.1126/sciadv.adg3683

Experimental method

SOLUTION NMR