8SN3
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 1) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-04-26 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SN8
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 6) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-04-26 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SN9
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 1) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-04-26 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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6RIE
| Structure of Vaccinia Virus DNA-dependent RNA polymerase co-transcriptional capping complex | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | Authors: | Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P. | Deposit date: | 2019-04-23 | Release date: | 2019-12-18 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell, 179, 2019
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7PY0
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in more-swiveled conformation) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-08 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY8
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in less-swiveled conformation) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-09 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY1
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (the consensus NusG-EC) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-08 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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4YLP
| E. coli Transcription Initiation Complex - 16-bp spacer and 5-nt RNA | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, Steitz, T.A. | Deposit date: | 2015-03-05 | Release date: | 2015-04-22 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble. Mol.Cell, 58, 2015
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4YLO
| E. coli Transcription Initiation Complex - 16-bp spacer and 4-nt RNA | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, Steitz, T.A. | Deposit date: | 2015-03-05 | Release date: | 2015-04-22 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (6 Å) | Cite: | Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble. Mol.Cell, 58, 2015
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6RQH
| RNA Polymerase I Closed Conformation 1 (CC1) | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | Deposit date: | 2019-05-15 | Release date: | 2019-12-11 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
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5IYA
| Human core-PIC in the closed state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY8
| Human holo-PIC in the initial transcribing state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY6
| Human holo-PIC in the closed state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IYD
| Human core-PIC in the initial transcribing state (no IIS) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IYB
| Human core-PIC in the open state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY7
| Human holo-PIC in the open state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (8.6 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY9
| Human holo-PIC in the initial transcribing state (no IIS) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IYC
| Human core-PIC in the initial transcribing state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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6TPS
| early intermediate RNA Polymerase I Pre-initiation complex - eiPIC | Descriptor: | DNA foreign, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, ... | Authors: | Pilsl, M, Engel, C. | Deposit date: | 2019-12-14 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting. Nat Commun, 11, 2020
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7RDQ
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6RQL
| RNA Polymerase I Closed Conformation 2 (CC2) | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | Deposit date: | 2019-05-16 | Release date: | 2019-12-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
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6RWE
| RNA Polymerase I Open Complex conformation 2 | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | Deposit date: | 2019-06-04 | Release date: | 2019-12-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
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4YLN
| E. coli Transcription Initiation Complex - 17-bp spacer and 4-nt RNA | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, Steitz, T.A. | Deposit date: | 2015-03-05 | Release date: | 2015-04-22 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble. Mol.Cell, 58, 2015
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6RUO
| RNA Polymerase I Open Complex conformation 1 | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Mueller, C.W, Sadian, Y, Tafur, L. | Deposit date: | 2019-05-28 | Release date: | 2019-12-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
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7MOO
| L-type DNA containing 2'-fluoro-2'-deoxycytidine | Descriptor: | DNA (5'-D(*(0DG)P*(OFC)P*(0DG)P*(0DT)P*(0DA)P*(0DC)P*(0DG)P*(0DC))-3') | Authors: | Dantsu, Y, Zhang, Y, Zhang, W. | Deposit date: | 2021-05-03 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Synthesis of 2'-Deoxy-2'-fluoro-L-cytidine and Fluorinated L-Nucleic Acids for Structural Studies Chemistryselect, 6, 2021
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