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2I99
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BU of 2i99 by Molmil
Crystal structure of human Mu_crystallin at 2.6 Angstrom
Descriptor: Mu-crystallin homolog, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cheng, Z, Sun, L, He, J, Gong, W.
Deposit date:2006-09-05
Release date:2007-02-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human {micro}-crystallin complexed with NADPH
Protein Sci., 16, 2007
4MIU
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BU of 4miu by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS V23T/V99T at cryogenic temperature
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Caro, J.A, Schlessman, J.L, Garcia-Moreno E, B.
Deposit date:2013-09-02
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Cavities in proteins
To be Published
4H69
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BU of 4h69 by Molmil
Crystal Structure of the Allene Oxide Cyclase 2 from Physcomitrella patens complexed with substrate analog
Descriptor: (9Z)-11-{(2R,3S)-3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}undec-9-enoic acid, Allene oxide cyclase, ISOPROPYL ALCOHOL, ...
Authors:Neumann, P, Ficner, R.
Deposit date:2012-09-19
Release date:2012-10-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Physcomitrella patens AOC1 and AOC2: Insights into the Enzyme Mechanism and Differences in Substrate Specificity.
Plant Physiol., 160, 2012
3NKM
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BU of 3nkm by Molmil
Crystal structure of mouse autotaxin
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NDM
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BU of 3ndm by Molmil
Crystal structure of Rho-Associated Protein Kinase (ROCK1) with a potent isoquinolone derivative
Descriptor: (3S,4R)-N-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide, Rho-Associated Protein Kinase (ROCK1)
Authors:Li, X.
Deposit date:2010-06-07
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines.
Bioorg.Med.Chem.Lett., 20, 2010
2F7M
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BU of 2f7m by Molmil
Crystal Structure of Unliganded Human FPPS
Descriptor: Farnesyl Diphosphate Synthase, PHOSPHATE ION
Authors:Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W.
Deposit date:2005-12-01
Release date:2006-02-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
3EV1
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BU of 3ev1 by Molmil
Crystal Structure of Ribonuclease A in 70% Hexanediol
Descriptor: HEXANE-1,6-DIOL, Ribonuclease pancreatic
Authors:Dechene, M, Wink, G, Smith, M, Swartz, P, Mattos, C.
Deposit date:2008-10-12
Release date:2009-06-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multiple solvent crystal structures of ribonuclease A: An assessment of the method
Proteins, 76, 2009
2I2O
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BU of 2i2o by Molmil
Crystal Structure of an eIF4G-like Protein from Danio rerio
Descriptor: NICKEL (II) ION, eIF4G-like protein
Authors:Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-08-16
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of an eIF4G-like protein from Danio rerio.
Proteins, 78, 2010
4N40
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BU of 4n40 by Molmil
Crystal structure of human Epithelial cell-transforming sequence 2 protein
Descriptor: Protein ECT2
Authors:Zou, Y, Shao, Z.H, Li, F.D, Gong, D, Wang, C, Gong, Q, Shi, Y.
Deposit date:2013-10-08
Release date:2014-08-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4
Febs Lett., 588, 2014
2PQ8
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BU of 2pq8 by Molmil
MYST histone acetyltransferase 1
Descriptor: COENZYME A, Probable histone acetyltransferase MYST1, UNKNOWN ATOM OR ION, ...
Authors:Tempel, W, Wu, H, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2007-05-01
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:MYST histone acetyltransferase 1.
To be Published
3ET9
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BU of 3et9 by Molmil
Crystal structure of the engineered neutralizing antibody 1H
Descriptor: Antibody 1H light chain and antibody 1H heavy chain linked with a synthetic (GGGGS)4 linker
Authors:Leysath, C.E, Monzingo, A.F, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
Deposit date:2008-10-07
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
2I3P
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BU of 2i3p by Molmil
K28R mutant of Homing Endonuclease I-CreI
Descriptor: 5'-D(*CP*GP*AP*AP*AP*TP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*AP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*TP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*AP*TP*TP*TP*CP*G)-3', CALCIUM ION, ...
Authors:Sussman, D, Rosen, L.
Deposit date:2006-08-20
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Homing endonuclease I-CreI derivatives with novel DNA target specificities.
Nucleic Acids Res., 34, 2006
3NHS
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BU of 3nhs by Molmil
X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2
Descriptor: 5,8-dimethoxy-4-methylquinolin-2(1H)-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ...
Authors:Sturdy, M.
Deposit date:2010-06-14
Release date:2012-01-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2
To be Published
4HDK
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BU of 4hdk by Molmil
Crystal Structure of ArsAB in Complex with Phloroglucinol
Descriptor: 1,2-ETHANEDIOL, ArsA, ArsB, ...
Authors:Newmister, S.A, Chan, C.H, Escalante-Semerena, J.C, Rayment, I.
Deposit date:2012-10-02
Release date:2012-10-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Insights into the Function of the Nicotinate Mononucleotide:phenol/p-cresol Phosphoribosyltransferase (ArsAB) Enzyme from Sporomusa ovata.
Biochemistry, 51, 2012
2F9Y
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BU of 2f9y by Molmil
The Crystal Structure of The Carboxyltransferase Subunit of ACC from Escherichia coli
Descriptor: Acetyl-CoA carboxylase, Carboxyltransferase alpha chain, Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ...
Authors:Bilder, P.W.
Deposit date:2005-12-06
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Structure of the Carboxyltransferase Component of Acetyl-CoA Carboxylase Reveals a Zinc-Binding Motif Unique to the Bacterial Enzyme(,).
Biochemistry, 45, 2006
4MP3
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BU of 4mp3 by Molmil
Staphyloferrin B precursor biosynthetic enzyme selenomethionine-labeled SbnB
Descriptor: GLYCEROL, Putative ornithine cyclodeaminase, SULFATE ION
Authors:Grigg, J.C, Kobylarz, M.J, Rai, D.K, Murphy, M.E.P.
Deposit date:2013-09-12
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Synthesis of L-2,3-diaminopropionic Acid, a siderophore and antibiotic precursor.
Chem.Biol., 21, 2014
3N1W
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BU of 3n1w by Molmil
Human FPPS COMPLEX WITH FBS_02
Descriptor: (5-chloro-1-benzothiophen-3-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION
Authors:Rondeau, J.-M.
Deposit date:2010-05-17
Release date:2010-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.
Nat.Chem.Biol., 6, 2010
4N53
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BU of 4n53 by Molmil
Human enterovirus 71 uncoating intermediate captured at atomic resolution
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Chen, R, Lyu, K.
Deposit date:2013-10-09
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3063 Å)
Cite:Human enterovirus 71 uncoating captured at atomic resolution.
J.Virol., 88, 2014
3ESV
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BU of 3esv by Molmil
Crystal structure of the engineered neutralizing antibody M18
Descriptor: Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker
Authors:Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
Deposit date:2008-10-06
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3EV5
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BU of 3ev5 by Molmil
Crystal Structure of Ribonuclease A in 1M Trimethylamine N-Oxide
Descriptor: Ribonuclease pancreatic, trimethylamine oxide
Authors:Dechene, M, Wink, G, Smith, M, Swartz, P, Mattos, C.
Deposit date:2008-10-12
Release date:2009-06-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Multiple solvent crystal structures of ribonuclease A: An assessment of the method
Proteins, 76, 2009
4MPO
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BU of 4mpo by Molmil
1.90 A resolution structure of CT771 from Chlamydia trachomatis Bound to Hydrolyzed Ap4A Products
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, CT771, ...
Authors:Barta, M.L, Lovell, S, Battaile, K.P, Hefty, P.S.
Deposit date:2013-09-13
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Chlamydia trachomatis CT771 (nudH) Is an Asymmetric Ap4A Hydrolase.
Biochemistry, 53, 2014
2IBJ
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BU of 2ibj by Molmil
Structure of House Fly Cytochrome B5
Descriptor: Cytochrome b5, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L.
Deposit date:2006-09-11
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Comparison of cytochromes b(5) from insects and vertebrates.
Proteins, 67, 2007
3MZV
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BU of 3mzv by Molmil
Crystal structure of a decaprenyl diphosphate synthase from Rhodobacter capsulatus
Descriptor: Decaprenyl diphosphate synthase
Authors:Quartararo, C.E, Patskovsky, Y, Bonanno, J.B, Rutter, M, Bain, K.T, Chang, S, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-05-13
Release date:2010-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HF3
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BU of 4hf3 by Molmil
Activity Enhancers of H64A Variant of Human Carbonic Anhydrase II Possess Multiple Binding Sites within and around the Enzyme Structure
Descriptor: Carbonic anhydrase 2, IMIDAZOLE, ZINC ION
Authors:Aggarwal, M, McKenna, R.
Deposit date:2012-10-04
Release date:2013-10-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.1476 Å)
Cite:Structural insight into activity enhancement and inhibition of H64A carbonic anhydrase II by imidazoles.
IUCrJ, 1, 2014
4MQF
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BU of 4mqf by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist 2-hydroxysaclofen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxysaclofen, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-16
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013

222624

數據於2024-07-17公開中

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