3WDR
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![BU of 3wdr by Molmil](/molmil-images/mine/3wdr) | Crystal structure of beta-mannanase from a symbiotic protist of the termite Reticulitermes speratus complexed with gluco-manno-oligosaccharide | Descriptor: | BICARBONATE ION, Beta-mannanase, MAGNESIUM ION, ... | Authors: | Tsukagoshi, H, Ishida, T, Touhara, K.K, Igarashi, K, Samejima, M, Fushinobu, S, Kitamoto, K, Arioka, M. | Deposit date: | 2013-06-20 | Release date: | 2014-03-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and Biochemical Analyses of Glycoside Hydrolase Family 26 beta-Mannanase from a Symbiotic Protist of the Termite Reticulitermes speratus J.Biol.Chem., 289, 2014
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2MQQ
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4FFB
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![BU of 4ffb by Molmil](/molmil-images/mine/4ffb) | A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule Polymerase | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein STU2, ... | Authors: | Ayaz, P, Ye, X, Huddleston, P, Brautigam, C.A, Rice, L.M. | Deposit date: | 2012-05-31 | Release date: | 2012-08-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.882 Å) | Cite: | A TOG: alpha beta-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase. Science, 337, 2012
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5IO6
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3WPK
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1N83
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![BU of 1n83 by Molmil](/molmil-images/mine/1n83) | Crystal Structure of the complex between the Orphan Nuclear Hormone Receptor ROR(alpha)-LBD and Cholesterol | Descriptor: | CHOLESTEROL, Nuclear receptor ROR-alpha | Authors: | Kallen, J.A, Schlaeppi, J.M, Bitsch, F, Geisse, S, Geiser, M, Delhon, I, Fournier, B. | Deposit date: | 2002-11-19 | Release date: | 2002-12-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | X-ray Structure of hROR(alpha) LBD at 1.63A: Structural and Functional data that Cholesterol or a Cholesterol derivative is the natural ligand of ROR(alpha) Structure, 10, 2002
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3WU7
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3WUA
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6FK2
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3AO4
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![BU of 3ao4 by Molmil](/molmil-images/mine/3ao4) | Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase | Descriptor: | 3-(1,3-benzodioxol-5-yl)-1-methyl-1H-pyrazol-5-amine, CADMIUM ION, CHLORIDE ION, ... | Authors: | Wielens, J, Headey, S.J, Parker, M.W, Chalmers, D.K, Scanlon, M.J. | Deposit date: | 2010-09-20 | Release date: | 2011-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
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3AO3
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![BU of 3ao3 by Molmil](/molmil-images/mine/3ao3) | Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase | Descriptor: | 3-(1,3-benzodioxol-5-yl)-1-methyl-1H-pyrazole-5-carboxylic acid, CADMIUM ION, CHLORIDE ION, ... | Authors: | Wielens, J, Headey, S.J, Parker, M.W, Chalmers, D.K, Scanlon, M.J. | Deposit date: | 2010-09-20 | Release date: | 2011-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
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2MW4
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![BU of 2mw4 by Molmil](/molmil-images/mine/2mw4) | Tetramerization domain of the Ciona intestinalis p53/p73-b transcription factor protein | Descriptor: | Transcription factor protein | Authors: | Heering, J.P, Jonker, H.R.A, Loehr, F, Schwalbe, H, Doetsch, V. | Deposit date: | 2014-10-27 | Release date: | 2015-10-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural investigations of the p53/p73 homologs from the tunicate species Ciona intestinalis reveal the sequence requirements for the formation of a tetramerization domain. Protein Sci., 25, 2016
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3WPL
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3MHG
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![BU of 3mhg by Molmil](/molmil-images/mine/3mhg) | Dihydroxyacetone phosphate carbanion intermediate in tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, CALCIUM ION, Tagatose 1,6-diphosphate aldolase 2 | Authors: | LowKam, C, Liotard, B. | Deposit date: | 2010-04-07 | Release date: | 2010-04-28 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structure of a class I tagatose-1,6-bisphosphate aldolase: investigation into an apparent loss of stereospecificity. J.Biol.Chem., 285, 2010
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4FAH
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![BU of 4fah by Molmil](/molmil-images/mine/4fah) | Crystal Structure of the Salicylate 1,2-dioxygenase from Pseudoaminobacter salicylatoxidans A85H mutant | Descriptor: | FE (III) ION, Gentisate 1,2-dioxygenase | Authors: | Ferraroni, M, Briganti, F, Matera, I. | Deposit date: | 2012-05-22 | Release date: | 2012-09-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The generation of a 1-hydroxy-2-naphthoate 1,2-dioxygenase by single point mutations of salicylate 1,2-dioxygenase - Rational design of mutants and the crystal structures of the A85H and W104Y variants. J.Struct.Biol., 180, 2012
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2I19
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![BU of 2i19 by Molmil](/molmil-images/mine/2i19) | T. Brucei farnesyl diphosphate synthase complexed with bisphosphonate | Descriptor: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, [2-(PYRIDIN-2-YLAMINO)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID) | Authors: | Cao, R, Mao, J, Gao, Y, Robinson, H, Odeh, S, Goddard, A, Oldfield, E. | Deposit date: | 2006-08-13 | Release date: | 2006-10-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. J.Am.Chem.Soc., 128, 2006
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4FBF
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![BU of 4fbf by Molmil](/molmil-images/mine/4fbf) | Crystal Structure of the Salicylate 1,2-dioxygenase from Pseudoaminobacter salicylatoxidans W104Y mutant | Descriptor: | FE (III) ION, Gentisate 1,2-dioxygenase | Authors: | Ferraroni, M, Briganti, F, Matera, I. | Deposit date: | 2012-05-23 | Release date: | 2012-09-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The generation of a 1-hydroxy-2-naphthoate 1,2-dioxygenase by single point mutations of salicylate 1,2-dioxygenase - Rational design of mutants and the crystal structures of the A85H and W104Y variants. J.Struct.Biol., 180, 2012
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3Q1H
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![BU of 3q1h by Molmil](/molmil-images/mine/3q1h) | Crystal Structure of Dihydrofolate Reductase from Yersinia pestis | Descriptor: | Dihydrofolate reductase, SULFATE ION | Authors: | Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-12-17 | Release date: | 2011-01-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.804 Å) | Cite: | Crystal Structure of Dihydrofolate Reductase from Yersinia pestis To be Published
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6FDJ
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2MQP
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5YWC
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5YW9
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3WDQ
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![BU of 3wdq by Molmil](/molmil-images/mine/3wdq) | Crystal structure of beta-mannanase from a symbiotic protist of the termite Reticulitermes speratus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-mannanase, MAGNESIUM ION, ... | Authors: | Tsukagoshi, H, Ishida, T, Touhara, K.K, Igarashi, K, Samejima, M, Fushinobu, S, Kitamoto, K, Arioka, M. | Deposit date: | 2013-06-20 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural and Biochemical Analyses of Glycoside Hydrolase Family 26 beta-Mannanase from a Symbiotic Protist of the Termite Reticulitermes speratus J.Biol.Chem., 289, 2014
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5YWB
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3W2Q
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![BU of 3w2q by Molmil](/molmil-images/mine/3w2q) | EGFR kinase domain T790M/L858R mutant with HKI-272 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide | Authors: | Sogabe, S, Kawakita, Y, Igaki, S. | Deposit date: | 2012-12-03 | Release date: | 2013-01-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors. Acs Med.Chem.Lett., 4, 2013
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