2DX0
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![BU of 2dx0 by Molmil](/molmil-images/mine/2dx0) | Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 | Descriptor: | Phospholipase C, gamma 2, SULFATE ION | Authors: | Handa, N, Takagi, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-08-22 | Release date: | 2007-09-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 To be Published
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3HMO
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![BU of 3hmo by Molmil](/molmil-images/mine/3hmo) | Crystal structure of human Mps1 catalytic domain in complex with the inhibitor staurosporine | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Dual specificity protein kinase TTK, GLYCEROL, ... | Authors: | Chu, M.L.H, Chavas, L.M.G, Williams, D.H, Tabernero, L, Eyers, P.A. | Deposit date: | 2009-05-29 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes. Biochemistry, 49, 2010
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2DQI
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![BU of 2dqi by Molmil](/molmil-images/mine/2dqi) | Crystal structure of hyhel-10 FV mutant (Ly50a) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-26 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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1UOS
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![BU of 1uos by Molmil](/molmil-images/mine/1uos) | The Crystal Structure of the Snake Venom Toxin Convulxin | Descriptor: | CONVULXIN ALPHA, CONVULXIN BETA | Authors: | Batuwangala, T, Leduc, M, Gibbins, J.M, Bon, C, Jones, E.Y. | Deposit date: | 2003-09-22 | Release date: | 2003-10-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the Snake-Venom Toxin Convulxin Acta Crystallogr.,Sect.D, 60, 2004
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2VNY
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![BU of 2vny by Molmil](/molmil-images/mine/2vny) | Structure of PKA-PKB chimera complexed with (1-(9H-Purin-6-yl) piperidin-4-yl)amine | Descriptor: | 1-(9H-purin-6-yl)piperidin-4-amine, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ... | Authors: | Caldwell, J.J, Davies, T.G, Donald, A, McHardy, T, Rowlands, M.G, Aherne, G.W, Hunter, L.K, Taylor, K, Ruddle, R, Raynaud, F.I, Verdonk, M, Workman, P, Garrett, M.D, Collins, I. | Deposit date: | 2008-02-08 | Release date: | 2008-04-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Identification of 4-(4-Aminopiperidin-1-Yl)-7H-Pyrrolo[2,3-D]Pyrimidines as Selective Inhibitors of Protein Kinase B Through Fragment Elaboration. J.Med.Chem., 51, 2008
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2XKD
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![BU of 2xkd by Molmil](/molmil-images/mine/2xkd) | Structure of Nek2 bound to aminopyrazine compound 12 | Descriptor: | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]benzoic acid, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2 | Authors: | Mas-Droux, C, Bayliss, R. | Deposit date: | 2010-07-07 | Release date: | 2010-10-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization. J.Med.Chem., 53, 2010
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2XM8
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![BU of 2xm8 by Molmil](/molmil-images/mine/2xm8) | Co-crystal structure of a small molecule inhibitor bound to the kinase domain of Chk2 | Descriptor: | 2-{4-[(3S)-PYRROLIDIN-3-YLAMINO]QUINAZOLIN-2-YL}PHENOL, SERINE/THREONINE-PROTEIN KINASE CHK2 | Authors: | Caldwell, J.J, Welsh, E.J, Matijssen, C, Anderson, V.E, Antoni, L, Boxall, K, Urban, F, Hayes, A, Raynaud, F.I, Rigoreau, L.J, Raynham, T, Aherne, G.W, Pearl, L.H, Oliver, A.W, Garrett, M.D, Collins, I. | Deposit date: | 2010-07-26 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2. J.Med.Chem., 54, 2011
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3VBQ
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![BU of 3vbq by Molmil](/molmil-images/mine/3vbq) | |
1SFI
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![BU of 1sfi by Molmil](/molmil-images/mine/1sfi) | High resolution structure of a potent, cyclic protease inhibitor from sunflower seeds | Descriptor: | CALCIUM ION, SULFATE ION, TRYPSIN, ... | Authors: | Luckett, S, Garcia, R.S, Barker, J.J, Konarev, A.V, Shewry, P, Clarke, A.R, Brady, R.L. | Deposit date: | 1998-12-16 | Release date: | 1999-07-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds. J.Mol.Biol., 290, 1999
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1JJJ
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![BU of 1jjj by Molmil](/molmil-images/mine/1jjj) | SOLUTION STRUCTURE OF RECOMBINANT HUMAN EPIDERMAL-TYPE FATTY ACID BINDING PROTEIN | Descriptor: | EPIDERMAL-TYPE FATTY ACID BINDING PROTEIN (E-FABP) | Authors: | Gutierrez-Gonzalez, L.H, Ludwig, C, Hohoff, C, Rademacher, M, Hanhoff, T, Rueterjans, H, Spener, F, Luecke, C. | Deposit date: | 2001-07-06 | Release date: | 2002-06-19 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of human epidermal-type fatty
acid-binding protein (E-FABP) BIOCHEM.J., 364, 2002
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2XMY
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![BU of 2xmy by Molmil](/molmil-images/mine/2xmy) | Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents | Descriptor: | 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | Authors: | Wang, S, Griffiths, G, Midgley, C.A, Barnett, A.L, Cooper, M, Grabarek, J, Ingram, L, Jackson, W, Kontopidis, G, McClue, S.J, McInnes, C, McLachlan, J, Meades, C, Mezna, M, Stuart, I, Thomas, M.P, Zheleva, D.I, Lane, D.P, Jackson, R.C, Glover, D.M, Blake, D.G, Fischer, P.M. | Deposit date: | 2010-07-29 | Release date: | 2010-11-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents Chem.Biol., 17, 2010
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2DHG
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![BU of 2dhg by Molmil](/molmil-images/mine/2dhg) | Solution structure of the C-terminal RNA recognition motif in tRNA selenocysteine associated protein | Descriptor: | tRNA selenocysteine associated protein (SECP43) | Authors: | Imai, T, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-23 | Release date: | 2006-09-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C-terminal RNA recognition motif in tRNA selenocysteine associated protein To be Published
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3HRC
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![BU of 3hrc by Molmil](/molmil-images/mine/3hrc) | |
1UVZ
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![BU of 1uvz by Molmil](/molmil-images/mine/1uvz) | |
2DJU
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![BU of 2dju by Molmil](/molmil-images/mine/2dju) | Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F | Descriptor: | Receptor-type tyrosine-protein phosphatase F | Authors: | Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-05 | Release date: | 2006-10-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F to be published
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2DLK
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![BU of 2dlk by Molmil](/molmil-images/mine/2dlk) | |
2DM0
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![BU of 2dm0 by Molmil](/molmil-images/mine/2dm0) | |
1JZK
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![BU of 1jzk by Molmil](/molmil-images/mine/1jzk) | Crystal Structure of Scapharca inaequivalvis HbI, I114F mutant (deoxy) | Descriptor: | GLOBIN I - ARK SHELL, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Knapp, J.E, Gibson, Q.H, Cushing, L, Royer Jr, W.E. | Deposit date: | 2001-09-16 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Restricting the Ligand-Linked Heme Movement in Scapharca Dimeric Hemoglobin Reveals Tight Coupling between Distal and Proximal
Contributions to Cooperativity. Biochemistry, 40, 2001
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2DML
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![BU of 2dml by Molmil](/molmil-images/mine/2dml) | The solution structure of the first thioredoxin domain of mouse Protein disulfide-isomerase A6 | Descriptor: | Protein disulfide-isomerase A6 | Authors: | Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-22 | Release date: | 2006-10-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The solution structure of the first thioredoxin domain of mouse Protein disulfide-isomerase A6 To be Published
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1UZ2
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![BU of 1uz2 by Molmil](/molmil-images/mine/1uz2) | The Cys121Ser Mutant of Beta-Lactoglobulin | Descriptor: | BETA-LACTOGLOBULIN | Authors: | McNae, I, Jayat, D, Haertle, T, Holt, C, Sawyer, L. | Deposit date: | 2004-03-03 | Release date: | 2004-05-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A recombinant C121S mutant of bovine beta-lactoglobulin is more susceptible to peptic digestion and to denaturation by reducing agents and heating. Biochemistry, 43, 2004
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2Y0A
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![BU of 2y0a by Molmil](/molmil-images/mine/2y0a) | Structure of DAPK1 construct residues 1-304 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DEATH-ASSOCIATED PROTEIN KINASE 1 | Authors: | Yumerefendi, H, Mas, P.J, Dordevic, N, McCarthy, A.A, Hart, D.J. | Deposit date: | 2010-12-01 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Library-Based Construct Screening of Death-Associated Protein Kinase 1 Identifies the Minimal Calmodulin Interaction Region and Autoinhibitory Conformation of the Catalytic Domain To be Published
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1UYU
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![BU of 1uyu by Molmil](/molmil-images/mine/1uyu) | Xenon COMPLEX OF wildtype P450CAM FROM PSEUDOMONAS PUTIDA | Descriptor: | CAMPHOR, CYTOCHROME P450-CAM, POTASSIUM ION, ... | Authors: | Wade, R.C, Winn, P.J, Schlichting, I, Sudarko, X. | Deposit date: | 2004-03-02 | Release date: | 2005-03-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Survey of Active Site Access Channels in Cytochromes P450 J.Inorg.Biochem., 98, 2004
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2DQG
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![BU of 2dqg by Molmil](/molmil-images/mine/2dqg) | Crystal structure of hyhel-10 FV mutant (Hy53f) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-25 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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2DGW
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![BU of 2dgw by Molmil](/molmil-images/mine/2dgw) | Solution structure of the second RNA recognition motif in RNA-binding protein 19 | Descriptor: | Probable RNA-binding protein 19 | Authors: | Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-16 | Release date: | 2006-09-16 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the second RNA recognition motif in RNA-binding protein 19 To be Published
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1HUN
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![BU of 1hun by Molmil](/molmil-images/mine/1hun) | |