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8IY4	Crystal structure of Class A beta-lactamase BlaA WT - complex with Meropenem Descriptor: (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION Authors: Bhattacharya, S, Hazra, S. Deposit date: 2023-04-03 Release date: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of Class A beta-lactamase BlaA WT - complex with Meropenem To be published
8J5V	Crystal structure of estZF172 as a novel biocatalyst for the efficient biosynthesis of a chiral intermediate of pregabalin Descriptor: Carboxylesterase Authors: Chi, C.B, Liang, Z.D, Huo, B.Q, Hu, C.X, Sun, Q.Y. Deposit date: 2023-04-24 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystal structure of estZF172 as a novel biocatalyst for the efficient biosynthesis of a chiral intermediate of pregabalin To Be Published
8J6Y	Crystal structure of class A beta-lactamase PSE-4 WT- Apo state Descriptor: Beta-lactamase PSE-4, SULFATE ION Authors: Sarkar, M, Bhattacharya, S, Hazra, S. Deposit date: 2023-04-26 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of class A beta-lactamase PSE-4 WT- Apo state To be published
8JB7	Crystal structure of CMY-185 Descriptor: Beta-lactamase, SULFATE ION Authors: Kawai, A, Doi, Y. Deposit date: 2023-05-08 Release date: 2023-12-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185. Mbio, 15, 2024
8JB8	Crystal structure of CMY-185 complex with ceftazidime Descriptor: ACYLATED CEFTAZIDIME, Beta-lactamase Authors: Kawai, A, Doi, Y. Deposit date: 2023-05-08 Release date: 2023-12-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185. Mbio, 15, 2024
8JK3	Crystal Structure of Bel-1 Extended Spectrum Beta-lactamase in Hexagonal Form Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Beta-lactamase, ... Authors: Dhankhar, K, Hazra, S. Deposit date: 2023-05-31 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of Bel-1 ESBL in Hexagonal Form To Be Published
8JOI	Crystal Structure of Bel-1 E166A Mutant. Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, Beta-lactamase, ... Authors: Dhankhar, K, Hazra, S. Deposit date: 2023-06-07 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of Bel-1 E166A Mutant To Be Published
8KEM	PKS domains-fused AmpC EC2 Descriptor: SDR family NAD(P)-dependent oxidoreductase,Beta-lactamase Authors: Son, S.Y, Bae, D.W, Cha, S.S. Deposit date: 2023-08-12 Release date: 2024-06-05 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (2.76998281 Å) Cite: Structural investigation of the docking domain assembly from trans-AT polyketide synthases. Structure, 2024
8OE1	Structure of P167S BlaC from Mycobacterium tuberculosis at pH 5 Descriptor: Beta-lactamase, GLYCEROL Authors: Sun, J, Chikunova, A, Ubbink, M. Deposit date: 2023-03-10 Release date: 2023-08-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase. Int.J.Biol.Macromol., 250, 2023
8OE5	Structure of P167S BlaC from Mycobacterium tuberculosis at pH 6.3 Descriptor: Beta-lactamase, CITRATE ANION, GLYCEROL Authors: Sun, J, Chikunova, A, Ubbink, M. Deposit date: 2023-03-10 Release date: 2023-08-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase. Int.J.Biol.Macromol., 250, 2023
8PC9	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 0 ms - native. Descriptor: Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCA	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 50 ms Descriptor: Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCB	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 80 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCC	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 100 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCD	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 150 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCE	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 250 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCF	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 500 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCG	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 2000 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCI	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 5000 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCJ	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 10000 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCK	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 0 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCL	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 50 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION, ... Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCM	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 80 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION, ... Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCN	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 100 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION, ... Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCO	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 150 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION, ... Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024

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