3LSR
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8UDL
| Human Mitochondrial DNA Polymerase Gamma Binary Complex | Descriptor: | DNA (5'-D(P*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*T)-3'), DNA polymerase subunit gamma-1, ... | Authors: | Park, J, Yin, Y.W. | Deposit date: | 2023-09-28 | Release date: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.37 Å) | Cite: | An interaction network in the polymerase active site is a prerequisite for Watson-Crick base pairing in Pol gamma. Sci Adv, 10, 2024
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6DKS
| Structure of the Rbpj-SHARP-DNA Repressor Complex | Descriptor: | DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | Authors: | Kovall, R.A, VanderWielen, B.D, Yuan, Z. | Deposit date: | 2018-05-30 | Release date: | 2019-01-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site. Cell Rep, 26, 2019
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7AMN
| Structure of LuxR with DNA (repression) | Descriptor: | DNA (5'-D(P*TP*AP*TP*TP*GP*AP*TP*AP*AP*AP*AP*TP*TP*AP*TP*CP*AP*AP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*TP*GP*AP*TP*AP*AP*TP*TP*TP*TP*AP*TP*CP*AP*AP*TP*A)-3'), HTH-type transcriptional regulator LuxR | Authors: | Liu, B, Reverter, D. | Deposit date: | 2020-10-09 | Release date: | 2021-03-31 | Last modified: | 2021-04-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression. Nucleic Acids Res., 49, 2021
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6BSE
| Glucocorticoid receptor bound to high cooperativity monomer sequence | Descriptor: | DNA (5'-D(P*AP*CP*CP*AP*CP*GP*TP*GP*TP*AP*CP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*AP*GP*TP*AP*CP*AP*CP*GP*TP*GP*G)-3'), Glucocorticoid receptor, ... | Authors: | Pufall, M.A. | Deposit date: | 2017-12-02 | Release date: | 2018-12-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | General and sequence-specific roles for DNA in glucocorticoid receptor DNA-binding stoichiometry To Be Published
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5HLH
| Crystal structure of the overoxidized AbfR bound to DNA | Descriptor: | DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator | Authors: | Liu, G, Liu, X, Gan, J, Yang, C.-G. | Deposit date: | 2016-01-15 | Release date: | 2017-01-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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8XAS
| Crystal structure of AtARR1-DBD in complex with a DNA fragment | Descriptor: | DNA (50-MER), Two-component response regulator ARR1 | Authors: | Li, J.X, Zhou, C.M, zhang, P, Wang, J.W. | Deposit date: | 2023-12-05 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.346 Å) | Cite: | The structure of B-ARR reveals the molecular basis of transcriptional activation by cytokinin. Proc.Natl.Acad.Sci.USA, 121, 2024
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7TEC
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5VA7
| Glucocorticoid Receptor DNA Binding Domain - IL11 AP-1 recognition element Complex | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*TP*GP*AP*GP*TP*CP*AP*GP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*CP*TP*GP*AP*CP*TP*CP*AP*CP*CP*CP*T)-3'), Glucocorticoid receptor, ... | Authors: | Weikum, E.R, Ortlund, E.A. | Deposit date: | 2017-03-24 | Release date: | 2017-08-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.153 Å) | Cite: | Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Nucleic Acids Res., 45, 2017
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5VA0
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5HLG
| Structure of reduced AbfR bound to DNA | Descriptor: | DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator | Authors: | Liu, G, Liu, X, Gan, J, Yang, C.G. | Deposit date: | 2016-01-15 | Release date: | 2017-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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4O9M
| Human DNA polymerase beta complexed with adenylated tetrahydrofuran (abasic site) containing DNA | Descriptor: | (5'-D(P*GP*TP*CP*GP*G)-3');, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), ... | Authors: | Caglayan, M, Batra, V.K, Sassa, A, Prasad, R, Wilson, S.H. | Deposit date: | 2014-01-02 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Role of polymerase beta in complementing aprataxin deficiency during abasic-site base excision repair. Nat.Struct.Mol.Biol., 21, 2014
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7AMT
| Structure of LuxR with DNA (activation) | Descriptor: | DNA (5'-D(P*AP*TP*AP*AP*TP*GP*AP*CP*AP*TP*TP*AP*CP*TP*GP*TP*AP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*TP*AP*CP*AP*GP*TP*AP*AP*TP*GP*TP*CP*AP*TP*TP*AP*T)-3'), HTH-type transcriptional regulator LuxR | Authors: | Liu, B, Reverter, D. | Deposit date: | 2020-10-09 | Release date: | 2021-03-31 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression. Nucleic Acids Res., 49, 2021
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7RSS
| Kod-RI incorporating DNA, n+2 | Descriptor: | DNA polymerase, Primer, Template | Authors: | Hajjar, M, Chim, N, Chaput, J.C. | Deposit date: | 2021-08-11 | Release date: | 2022-08-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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5OGU
| Structure of DNA-binding HU protein from micoplasma Spiroplasma melliferum | Descriptor: | DNA-binding protein | Authors: | Altukhov, D.A, Talyzina, A.A, Agapova, Y.K, Vlaskina, A.V, Korzhenevskiy, D.A, Bocharov, E.V, Rakitina, T.V, Timofeev, V.I. | Deposit date: | 2017-07-13 | Release date: | 2017-08-23 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural plasticity and thermal stability of the histone-like protein from Spiroplasma melliferum are due to phenylalanine insertions into the conservative scaffold. J.Biomol.Struct.Dyn., 36, 2018
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1LMB
| REFINED 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR-OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*CP*CP*AP*CP*TP*GP*GP*CP*GP*GP*TP*GP*A P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*TP*CP*AP*CP*CP*GP*CP*CP*AP*GP*TP*GP*G P*TP*AP*T)-3'), PROTEIN (LAMBDA REPRESSOR) | Authors: | Beamer, L.J, Pabo, C.O. | Deposit date: | 1991-11-05 | Release date: | 1991-11-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Refined 1.8 A crystal structure of the lambda repressor-operator complex. J.Mol.Biol., 227, 1992
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7VOX
| The crystal structure of human forkhead box protein A in complex with DNA 2 | Descriptor: | DNA (5'-D(P*AP*AP*AP*TP*AP*TP*TP*TP*AP*TP*TP*AP*TP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*AP*TP*AP*AP*TP*AP*AP*AP*TP*AP*TP*TP*T)-3'), Hepatocyte nuclear factor 3-alpha, ... | Authors: | Choi, Y, Yoon, H.J, Lee, H.H. | Deposit date: | 2021-10-15 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations. Nucleic Acids Res., 50, 2022
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7VOU
| The crystal structure of human forkhead box protein in complex with DNA 1 | Descriptor: | DNA (5'-D(*AP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*T)-3'), Forkhead box protein L2 | Authors: | Choi, Y, Yoon, H.J, Lee, H.H. | Deposit date: | 2021-10-14 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations. Nucleic Acids Res., 50, 2022
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6A5M
| Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 2 | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6A5K
| Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1 | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5IJL
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5D8K
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1LCC
| STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS | Descriptor: | DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ... | Authors: | Chuprina, V.P, Rullmann, J.A.C, Lamerichs, R.M.J.N, Van Boom, J.H, Boelens, R, Kaptein, R. | Deposit date: | 1993-03-25 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. J.Mol.Biol., 234, 1993
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3CRO
| THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION | Descriptor: | DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*AP*AP*CP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*GP*TP*TP*TP*GP*T P*AP*CP*T)-3'), PROTEIN (434 CRO) | Authors: | Mondragon, A, Harrison, S.C. | Deposit date: | 1990-07-06 | Release date: | 1991-10-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The phage 434 Cro/OR1 complex at 2.5 A resolution. J.Mol.Biol., 219, 1991
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8HML
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