3HP2
 
 | | Crystal Structure of Human p38alpha complexed with a pyridinone compound | | Descriptor: | 1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1H)-one, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, Mitogen-activated protein kinase 14 | | Authors: | Shieh, H.-S, Williams, J.M, Stegeman, R.A, Kurumbail, R.G. | | Deposit date: | 2009-06-03 | | Release date: | 2009-09-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase.
Bioorg.Med.Chem.Lett., 19, 2009
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4X2S
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6WTX
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6OL1
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6M6K
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6M6J
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4LD7
 | | Crystal structure of AnaPT from Neosartorya fischeri | | Descriptor: | Dimethylallyl tryptophan synthase, SODIUM ION, TRIHYDROGEN THIODIPHOSPHATE | | Authors: | Zocher, G, Stehle, T. | | Deposit date: | 2013-06-24 | | Release date: | 2013-12-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Catalytic Mechanism of Stereospecific Formation of cis-Configured Prenylated Pyrroloindoline Diketopiperazines by Indole Prenyltransferases.
Chem.Biol., 20, 2013
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6IY5
 | | NMR solution structures of 5'-ATTCTATTCT-3 | | Descriptor: | DNA (5'-D(*AP*TP*TP*CP*TP*AP*TP*TP*CP*T)-3'), SODIUM ION | | Authors: | Lam, S.L, Guo, P. | | Deposit date: | 2018-12-13 | | Release date: | 2020-06-10 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Minidumbbell structures formed by ATTCT pentanucleotide repeats in spinocerebellar ataxia type 10.
Nucleic Acids Res., 48, 2020
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6X2Z
 | | hEAAT3-OFS-Asp | | Descriptor: | ASPARTIC ACID, Excitatory amino acid transporter 3, SODIUM ION | | Authors: | Qiu, B, Matthies, D, Boudker, O. | | Deposit date: | 2020-05-21 | | Release date: | 2021-03-17 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport.
Sci Adv, 7, 2021
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6X3E
 | | hEAAT3-Asymmetric-1o2i | | Descriptor: | ASPARTIC ACID, Excitatory amino acid transporter 3, SODIUM ION | | Authors: | Qiu, B, Matthies, D, Boudker, O. | | Deposit date: | 2020-05-21 | | Release date: | 2021-03-17 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport.
Sci Adv, 7, 2021
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6J37
 | | DNA minidumbbell structure of two CTTG repeats | | Descriptor: | DNA (5'-D(*CP*TP*TP*GP*CP*TP*TP*G)-3'), SODIUM ION | | Authors: | Lam, S.L, Guo, P. | | Deposit date: | 2019-01-04 | | Release date: | 2019-05-29 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Unprecedented hydrophobic stabilizations from a reverse wobble T·T mispair in DNA minidumbbell.
J.Biomol.Struct.Dyn., 38, 2020
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6BAU
 | | Crystal Structure of GltPh R397C in complex with L-Cysteine | | Descriptor: | CYSTEINE, Glutamate transporter homolog, SODIUM ION | | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | | Deposit date: | 2017-10-15 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
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6BAT
 | | Crystal Structure of Wild-Type GltPh in complex with L-aspartate | | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | | Deposit date: | 2017-10-15 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
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6M0C
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6M0B
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6V8G
 | | GltPh mutant - Y204L A345V V366A | | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | | Authors: | Boudker, O, Huysmans, G.H.M. | | Deposit date: | 2019-12-11 | | Release date: | 2020-11-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.38 Å) | | Cite: | The high-energy transition state of the glutamate transporter homologue GltPh.
Embo J., 40, 2021
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5GWL
 | | Structure of two CCTG repeats | | Descriptor: | DNA (5'-D(*CP*CP*TP*GP*CP*CP*TP*G)-3'), SODIUM ION | | Authors: | Guo, P, Lam, S.L. | | Deposit date: | 2016-09-12 | | Release date: | 2016-10-12 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Minidumbbell: A New Form of Native DNA Structure
J.Am.Chem.Soc., 138, 2016
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5GWQ
 | | Structure of two TTTA repeats | | Descriptor: | DNA (5'-D(*TP*TP*TP*AP*TP*TP*TP*A)-3'), SODIUM ION | | Authors: | Guo, P, Lam, S.L. | | Deposit date: | 2016-09-13 | | Release date: | 2016-10-12 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Minidumbbell: A New Form of Native DNA Structure
J.Am.Chem.Soc., 138, 2016
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6BMI
 | | Crystal Structure of GltPh R397C in complex with L-Serine | | Descriptor: | Glutamate transporter homolog, SERINE, SODIUM ION | | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | | Deposit date: | 2017-11-14 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
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8SGT
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4D1Q
 | | Hermes transposase bound to its terminal inverted repeat | | Descriptor: | SODIUM ION, TERMINAL INVERTED REPEAT, TRANSPOSASE | | Authors: | Hickman, A.B, Ewis, H, Li, X, Knapp, J, Laver, T, Doss, A.L, Tolun, G, Steven, A, Grishaev, A, Bax, A, Atkinson, P, Craig, N.L, Dyda, F. | | Deposit date: | 2014-05-04 | | Release date: | 2014-07-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural Basis of Hat Transposon End Recognition by Hermes, an Octameric DNA Transposase from Musca Domestica.
Cell(Cambridge,Mass.), 158, 2014
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6CTF
 | | Crystal structure of GltPh fast mutant - R276S/M395R | | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | | Authors: | Boudker, O, Oh, S. | | Deposit date: | 2018-03-23 | | Release date: | 2018-10-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (4.05 Å) | | Cite: | Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh.
Elife, 7, 2018
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6BAV
 | | Crystal Structure of GltPh R397C in complex with S-Benzyl-L-Cysteine | | Descriptor: | BENZYLCYSTEINE, Glutamate transporter homolog, SODIUM ION | | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | | Deposit date: | 2017-10-16 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
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3V8G
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7E4E
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