7P9T
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![BU of 7p9t by Molmil](/molmil-images/mine/7p9t) | Crystal structure of CD73 in complex with dCMP in the open form | Descriptor: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 5'-nucleotidase, CALCIUM ION, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-27 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7PB5
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![BU of 7pb5 by Molmil](/molmil-images/mine/7pb5) | Crystal structure of CD73 in complex with UMP in the open form | Descriptor: | 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-30 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7PBA
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![BU of 7pba by Molmil](/molmil-images/mine/7pba) | Crystal structure of CD73 in complex with IMP in the open form | Descriptor: | 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-08-01 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7PA4
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![BU of 7pa4 by Molmil](/molmil-images/mine/7pa4) | Crystal structure of CD73 in complex with CMP in the open form | Descriptor: | 5'-nucleotidase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-28 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7PBB
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![BU of 7pbb by Molmil](/molmil-images/mine/7pbb) | |
7P9N
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![BU of 7p9n by Molmil](/molmil-images/mine/7p9n) | Crystal structure of CD73 in complex with AMP in the open form | Descriptor: | 5'-nucleotidase, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-27 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7P9R
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![BU of 7p9r by Molmil](/molmil-images/mine/7p9r) | Crystal structure of CD73 in complex with GMP in the open form | Descriptor: | 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... | Authors: | Scaletti, E.R, Strater, N. | Deposit date: | 2021-07-27 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
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7PBY
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1GMK
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![BU of 1gmk by Molmil](/molmil-images/mine/1gmk) | GRAMICIDIN/KSCN COMPLEX | Descriptor: | GRAMICIDIN A, METHANOL, POTASSIUM ION, ... | Authors: | Doyle, D.A, Wallace, B.A. | Deposit date: | 1996-07-09 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the Gramicidin/Potassium Thiocyanate Complex. J.Mol.Biol., 266, 1997
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1GON
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![BU of 1gon by Molmil](/molmil-images/mine/1gon) | b-glucosidase from Streptomyces sp | Descriptor: | BETA-GLUCOSIDASE, MERCURY (II) ION, SULFATE ION | Authors: | Guasch, A, Perez-Pons, J.A, Vallmitjana, M, Querol, E, Coll, M. | Deposit date: | 2001-10-22 | Release date: | 2002-11-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of a Family 1 Beta-Glucosidase from Streptomyces To be Published
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1GNX
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![BU of 1gnx by Molmil](/molmil-images/mine/1gnx) | b-glucosidase from Streptomyces sp | Descriptor: | BETA-GLUCOSIDASE, SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | Authors: | Guasch, A, Perez-Pons, J.A, Vallmitjana, M, Querol, E, Coll, M. | Deposit date: | 2001-10-10 | Release date: | 2002-10-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Beta-Glucosidase from Streptomyces To be Published
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1GRM
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![BU of 1grm by Molmil](/molmil-images/mine/1grm) | REFINEMENT OF THE SPATIAL STRUCTURE OF THE GRAMICIDIN A TRANSMEMBRANE ION-CHANNEL (RUSSIAN) | Descriptor: | GRAMICIDIN A | Authors: | Arseniev, A.S, Barsukov, I.L, Lomize, A.L, Orekhov, V.Y, Bystrov, V.F. | Deposit date: | 1993-10-18 | Release date: | 1994-01-31 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Refinement of the Spatial Structure of the Gramicidin a Ion Channel Biol.Membr.(Ussr), 18, 1992
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1GNV
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1GYC
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![BU of 1gyc by Molmil](/molmil-images/mine/1gyc) | CRYSTAL STRUCTURE DETERMINATION AT ROOM TEMPERATURE OF A LACCASE FROM TRAMETES VERSICOLOR IN ITS OXIDISED FORM CONTAINING A FULL COMPLEMENT OF COPPER IONS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | Authors: | Choinowski, T, Antorini, M, Piontek, K. | Deposit date: | 2002-04-23 | Release date: | 2002-08-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of a Laccase from the Fungus Trametes Versicolor at 1.90-A Resolution Containing a Full Complement of Coppers. J.Biol.Chem., 277, 2002
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1GSB
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1GW0
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![BU of 1gw0 by Molmil](/molmil-images/mine/1gw0) | Crystal Structure of Laccase from Melanocarpus albomyces in Four Copper Form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Hakulinen, N, Kiiskinen, L.-L, Kruus, K, Saloheimo, M, Koivula, A, Rouvinen, J. | Deposit date: | 2002-03-01 | Release date: | 2002-07-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of a Laccase from Melanocarpus Albomyces with an Intact Trinuclear Copper Site Nat.Struct.Biol., 9, 2002
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1H0V
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![BU of 1h0v by Molmil](/molmil-images/mine/1h0v) | Human cyclin dependent protein kinase 2 in complex with the inhibitor 2-Amino-6-[(R)-pyrrolidino-5'-yl]methoxypurine | Descriptor: | 5-{[(2-AMINO-9H-PURIN-6-YL)OXY]METHYL}-2-PYRROLIDINONE, CELL DIVISION PROTEIN KINASE 2 | Authors: | Gibson, A.E, Arris, C.E, Bentley, J, Boyle, F.T, Curtin, N.J, Davies, T.G, Endicott, J.A, Golding, B.T, Grant, S, Griffin, R.J, Jewsbury, P, Johnson, L.N, Mesguiche, V, Newell, D.R, Noble, M.E.M, Tucker, J.A, Whitfield, H.J. | Deposit date: | 2002-06-27 | Release date: | 2003-06-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives J.Med.Chem., 45, 2002
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1GNS
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![BU of 1gns by Molmil](/molmil-images/mine/1gns) | SUBTILISIN BPN' | Descriptor: | ACETONE, SUBTILISIN BPN' | Authors: | Almog, O, Gallagher, D.T, Ladner, J.E, Strausberg, S, Alexander, P. | Deposit date: | 2001-10-06 | Release date: | 2002-06-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis of Thermostability. Analysis of Stabilizing Mutations in Subtilisin Bpn'. J.Biol.Chem., 277, 2002
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1GZ8
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![BU of 1gz8 by Molmil](/molmil-images/mine/1gz8) | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 2-Amino-6-(3'-methyl-2'-oxo)butoxypurine | Descriptor: | 1-[(2-AMINO-6,9-DIHYDRO-1H-PURIN-6-YL)OXY]-3-METHYL-2-BUTANOL, CELL DIVISION PROTEIN KINASE 2 | Authors: | Davies, T, Endicott, J, Johnson, L, Noble, M, Tucker, J. | Deposit date: | 2002-05-17 | Release date: | 2003-06-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives J.Med.Chem., 45, 2002
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1H0W
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![BU of 1h0w by Molmil](/molmil-images/mine/1h0w) | Human cyclin dependent protein kinase 2 in complex with the inhibitor 2-Amino-6-[cyclohex-3-enyl]methoxypurine | Descriptor: | 1-AMINO-6-CYCLOHEX-3-ENYLMETHYLOXYPURINE, CELL DIVISION PROTEIN KINASE 2 | Authors: | Gibson, A.E, Arris, C.E, Bentley, J, Boyle, F.T, Curtin, N.J, Davies, T.G, Endicott, J.A, Golding, B.T, Grant, S, Griffin, R.J, Jewsbury, P, Johnson, L.N, Mesguiche, V, Newell, D.R, Noble, M.E.M, Tucker, J.A, Whitfield, H.J. | Deposit date: | 2002-06-27 | Release date: | 2003-06-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives J.Med.Chem., 45, 2002
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1GSC
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1HFU
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![BU of 1hfu by Molmil](/molmil-images/mine/1hfu) | TYPE-2 CU-DEPLETED LACCASE FROM COPRINUS CINEREUS at 1.68 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, LACCASE 1, ... | Authors: | Ducros, V, Brzozowski, A.M. | Deposit date: | 2000-12-08 | Release date: | 2001-12-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structure of the Laccase from Coprinus Cinereus at 1.68A Resolution: Evidence for Different Type 2 Cu-Depleted Isoforms Acta Crystallogr.,Sect.D, 57, 2001
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1GZL
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![BU of 1gzl by Molmil](/molmil-images/mine/1gzl) | Crystal structure of C14linkmid/IQN17: a cross-linked inhibitor of HIV-1 entry bound to the gp41 hydrophobic pocket | Descriptor: | CHLORIDE ION, ENVELOPE GLYCOPROTEIN GP41, FUSION PROTEIN BETWEEN THE HYDROPHOBIC POCKET OF HIV GP41 AND GENERAL CONTROL PROTEIN GCN4-PIQI, ... | Authors: | Sia, S.K, Carr, P.A, Cochran, A.G, Malashkevich, V.M, Kim, P.S. | Deposit date: | 2002-05-23 | Release date: | 2002-10-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Short Constrained Peptides that Inhibit HIV-1 Entry Proc.Natl.Acad.Sci.USA, 99, 2002
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1H00
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![BU of 1h00 by Molmil](/molmil-images/mine/1h00) | CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor | Descriptor: | (2R)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, (2S)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2 | Authors: | Beattie, J.F, Breault, G.A, Ellston, R.P.A, Green, S, Jewsbury, P.J, Midgley, C.J, Naven, R.T, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E. | Deposit date: | 2002-06-10 | Release date: | 2003-07-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines Bioorg.Med.Chem.Lett., 13, 2003
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1GY3
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![BU of 1gy3 by Molmil](/molmil-images/mine/1gy3) | pCDK2/cyclin A in complex with MgADP, nitrate and peptide substrate | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ... | Authors: | Cook, A, Lowe, E.D, Chrysina, E.D, Skamnaki, V.T, Oikonomakos, N.G, Johnson, L.N. | Deposit date: | 2002-04-19 | Release date: | 2002-04-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Studies on Phospho-Cdk2/Cyclin a Bound to Nitrate, a Transition State Analogue: Implications for the Protein Kinase Mechanism Biochemistry, 41, 2002
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