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7JPO
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BU of 7jpo by Molmil
ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPS
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BU of 7jps by Molmil
ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*T)-3'), ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPT
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BU of 7jpt by Molmil
Structure of an endocytic receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 75, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Gully, B.S, Rossjohn, J, Berry, R.
Deposit date:2020-08-09
Release date:2020-12-09
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The cryo-EM structure of the endocytic receptor DEC-205.
J.Biol.Chem., 296, 2020
7JPL
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Rabbit Cav1.1 in the presence of 10 micromolar (S)-(-)-Bay K8644 in nanodiscs at 3.4 Angstrom resolution
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, ...
Authors:Yan, N, Gao, S.
Deposit date:2020-08-09
Release date:2020-11-18
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca v 1.1 by Dihydropyridine Compounds*.
Angew.Chem.Int.Ed.Engl., 60, 2021
7JPK
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Rabbit Cav1.1 in the presence of 100 micromolar (S)-(-)-Bay K8644 in nanodiscs at 3.0 Angstrom resolution
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, ...
Authors:Yan, N, Gao, S.
Deposit date:2020-08-09
Release date:2020-11-18
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca v 1.1 by Dihydropyridine Compounds*.
Angew.Chem.Int.Ed.Engl., 60, 2021
7JPU
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BU of 7jpu by Molmil
Structure of an endocytic receptor
Descriptor: Lymphocyte antigen 75
Authors:Gully, B.S, Rossjohn, J, Berry, R.
Deposit date:2020-08-09
Release date:2020-12-09
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (5 Å)
Cite:The cryo-EM structure of the endocytic receptor DEC-205.
J.Biol.Chem., 296, 2020
7JPR
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BU of 7jpr by Molmil
ORC-OPEN: Human Origin Recognition Complex (ORC) in an open conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7A09
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BU of 7a09 by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State III
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-08-07
Release date:2020-10-14
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
7A0E
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BU of 7a0e by Molmil
The Crystal Structure of Bovine Thrombin in complex with Hirudin (C6U/C14U) at 1.9 Angstroms Resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin variant-1, Prothrombin, ...
Authors:Hidmi, T, Mousa, R, Pomyalov, S, Lansky, S, Khouri, L, Metanis, N, Shoham, G.
Deposit date:2020-08-07
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Diselenide crosslinks for enhanced and simplified oxidative protein folding
Commun Chem, 4, 2021
7A0D
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BU of 7a0d by Molmil
The Crystal Structure of Bovine Thrombin in complex with Hirudin (C16U/C28U) at 1.6 Angstroms Resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin variant-1, Prothrombin, ...
Authors:Hidmi, T, Mousa, R, Pomyalov, S, Lansky, S, Khouri, L, Metanis, N, Shoham, G.
Deposit date:2020-08-07
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Diselenide crosslinks for enhanced and simplified oxidative protein folding
Commun Chem, 4, 2021
7A0F
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BU of 7a0f by Molmil
The Crystal Structure of Bovine Thrombin in complex with Hirudin (C22U/C39U) at 2.7 Angstroms Resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin variant-1, Prothrombin, ...
Authors:Hidmi, T, Mousa, R, Pomyalov, S, Lansky, S, Khouri, L, Metanis, N, Shoham, G.
Deposit date:2020-08-07
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Diselenide crosslinks for enhanced and simplified oxidative protein folding
Commun Chem, 4, 2021
7CPQ
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BU of 7cpq by Molmil
crystal structure of T2R-TTL-(+)-6-Cl-JP18 complex
Descriptor: (6R)-6-[(6-chloranyl-1H-indol-3-yl)methyl]-6,7,8,9-tetrahydrobenzo[7]annulen-5-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Jiang, H, Luo, C.
Deposit date:2020-08-07
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:crystal structure of T2R-TTL-(+)-6-Cl-JP18 complex
To Be Published
7JP3
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BU of 7jp3 by Molmil
Des-B29,B30-insulin
Descriptor: CHLORIDE ION, Insulin B chain,Insulin A chain, PHENOL, ...
Authors:Yoder, J, Weiss, M.A, DiMarchi, R, Zaykov, A.
Deposit date:2020-08-07
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Des-B29,B30-insulin
To Be Published
7JOR
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BU of 7jor by Molmil
Neutron structure of ferric Dehaloperoxidase B
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE
Authors:Carey, L.M, Ghiladi, R.A, Meilleur, F, Myles, D.A.A.
Deposit date:2020-08-07
Release date:2021-09-08
Last modified:2024-04-03
Method:NEUTRON DIFFRACTION (2.05 Å)
Cite:Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature.
Iucrj, 9, 2022
7JOU
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BU of 7jou by Molmil
CRYSTAL STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK1) IN COMPLEX WITH A PHENYLPYRAZOLE AMIDE INHIBITOR
Descriptor: N-[(1S)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1H-pyrazol-4-yl)benzamide, Rho-associated protein kinase 1
Authors:Muckelbauer, J.K.
Deposit date:2020-08-07
Release date:2020-09-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.318 Å)
Cite:Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies.
Bioorg.Med.Chem.Lett., 30, 2020
7JOV
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BU of 7jov by Molmil
CRYSTAL STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE 2 (ROCK2) IN COMPLEX WITH A PHENYLPYRAZOLE AMIDE INHIBITOR
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, N-[(1S)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1H-pyrazol-4-yl)benzamide, ...
Authors:Muckelbauer, J.K.
Deposit date:2020-08-07
Release date:2020-09-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies.
Bioorg.Med.Chem.Lett., 30, 2020
7JOW
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BU of 7jow by Molmil
Crystal structure of BbKI complexed with Human Kallikrein 4
Descriptor: CADMIUM ION, CHLORIDE ION, Kallikrein 4 (Prostase, ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-07
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
7JOS
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BU of 7jos by Molmil
Crystal structure of BbKI complexed with Human Kallikrein 4
Descriptor: Kallikrein 4 (Prostase, enamel matrix, prostate), ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-07
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
7JOZ
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BU of 7joz by Molmil
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
Descriptor: 6-{4-[(furo[3,2-c]pyridin-4-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione, Endolysin,D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Sun, B, Feng, D, Chu, M.L, Fish, I, Kelm, S, Lebon, F, Lovera, S, Valade, A, Wood, M, Ceska, T, Kobilka, T.S, Sands, Z, Kobilka, B.K.
Deposit date:2020-08-07
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist.
Nat Commun, 12, 2021
7CP4
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BU of 7cp4 by Molmil
Crystal Structure of PAK4 in complex with inhibitor 55
Descriptor: Serine/threonine-protein kinase PAK 4, [1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indol-3-yl]-[(3S)-3-methylpiperazin-1-yl]methanone
Authors:Zhao, F, Li, H.
Deposit date:2020-08-06
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of 6-ethynyl-1H-indole-3-carboxamide Derivatives as Highly Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors
to be published
7CPD
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BU of 7cpd by Molmil
Crystal structure of T2R-TTL-(+)-6-Br-JP18 complex
Descriptor: (6R)-6-[(6-bromanyl-1H-indol-3-yl)methyl]-6,7,8,9-tetrahydrobenzo[7]annulen-5-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Jiang, H, Luo, C.
Deposit date:2020-08-06
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Crystal structure of T2R-TTL-(+)-6-Br-JP18 complex
To Be Published
7CP8
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BU of 7cp8 by Molmil
Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-1-Indanylamine
Descriptor: (2~{S})-2-(5-cyclohexylpentanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, ...
Authors:Stanfield, J.K, Sugimoto, H, Shoji, O.
Deposit date:2020-08-06
Release date:2021-09-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-1-Indanylamine at 1.68 Angstrom Resolution
To Be Published
7JOE
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BU of 7joe by Molmil
Crystal structure of BbKI complexed with Human Kallikrein 4
Descriptor: Kallikrein 4 (Prostase, enamel matrix, prostate), ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-06
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
7JOD
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BU of 7jod by Molmil
Crytsal structure of BbKI complexed with Human Kallikrein 4
Descriptor: CADMIUM ION, CHLORIDE ION, Kallikrein 4 (Prostase, ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-06
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
6ZZR
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BU of 6zzr by Molmil
The Crystal Structure of human LDHA from Biortus.
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L-lactate dehydrogenase A chain
Authors:Wang, F, Lin, D, Cheng, W, Bao, X, Zhu, B, Shang, H.
Deposit date:2020-08-05
Release date:2020-08-19
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The Crystal Structure of human LDHA from Biortus
To Be Published

222415

數據於2024-07-10公開中

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