7JOZ

Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist

Summary for 7JOZ

Entry DOI	10.2210/pdb7joz/pdb
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
Functional Keywords	dopamine receptor, d1, non-catechol agonist, g protein, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	168532.46
Authors	Sun, B.,Feng, D.,Chu, M.L.,Fish, I.,Kelm, S.,Lebon, F.,Lovera, S.,Valade, A.,Wood, M.,Ceska, T.,Kobilka, T.S.,Sands, Z.,Kobilka, B.K. (deposition date: 2020-08-07, release date: 2021-04-14, Last modification date: 2023-10-18)
Primary citation	Sun, B.,Feng, D.,Chu, M.L.,Fish, I.,Lovera, S.,Sands, Z.A.,Kelm, S.,Valade, A.,Wood, M.,Ceska, T.,Kobilka, T.S.,Lebon, F.,Kobilka, B.K. Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist. Nat Commun, 12:3305-3305, 2021 Cited by PubMed: 34083522 DOI: 10.1038/s41467-021-23519-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.8 Å)

Structure validation