PDB: 26618 resultsInfo pagesStatus searchChemie searchBIRD

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2B4E	Crystal Structure of Murine Coronin-1: monoclinic form Descriptor: Coronin-1A Authors: Appleton, B.A, Wu, P, Wiesmann, C. Deposit date: 2005-09-23 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes Structure, 14, 2006
1NR0	Two Seven-Bladed Beta-Propeller Domains Revealed By The Structure Of A C. elegans Homologue Of Yeast Actin Interacting Protein 1 (AIP1). Descriptor: Actin interacting protein 1, MANGANESE (II) ION Authors: Vorobiev, S.M, Mohri, K, Ono, S, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2003-01-23 Release date: 2003-07-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Identification of Functional Residues on Caenorhabditis elegans Actin-interacting Protein 1 (UNC-78) for Disassembly of Actin Depolymerizing Factor/Cofilin-bound Actin Filaments J.Biol.Chem., 279, 2004
8UQO	PLCb3-Gbg-Gaq complex on membranes Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Falzone, M.E, MacKinnon, R. Deposit date: 2023-10-24 Release date: 2023-12-06 Method: ELECTRON MICROSCOPY (3.37 Å) Cite: The mechanism of G alpha q regulation of PLC beta 3 -catalyzed PIP2 hydrolysis. Proc.Natl.Acad.Sci.USA, 120, 2023
8UJY	Crystal structure of human WD repeat-containing protein 5 in complex with 4-(3,5-dimethoxybenzyl)-9-(4-fluoro-2-methylphenyl)-7-((2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl)methyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (compound 8) Descriptor: (9P)-4-[(3,5-dimethoxyphenyl)methyl]-9-(4-fluoro-2-methylphenyl)-7-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}-3,4-dihydro-1,4-benzoxazepin-5(2H)-one, WD repeat-containing protein 5 Authors: Zhao, B, Amporndanai, K, Fesik, S.W. Deposit date: 2023-10-11 Release date: 2023-12-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors. J.Med.Chem., 66, 2023
2BCJ	Crystal Structure of G Protein-Coupled Receptor Kinase 2 in Complex with Galpha-q and Gbetagamma Subunits Descriptor: G-protein-coupled receptor kinase 2, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Tesmer, J.J.G. Deposit date: 2005-10-19 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.061 Å) Cite: Snapshot of Activated G Proteins at the Membrane: The Gq-GRK2-G Complex Science, 310, 2005
1KMN	HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDINOL AND ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, HISTIDYL-TRNA SYNTHETASE, L-histidinol Authors: Arnez, J.G, Francklyn, C.S, Moras, D. Deposit date: 1997-05-09 Release date: 1997-12-17 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase. Proc.Natl.Acad.Sci.USA, 94, 1997
1KMM	HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDYL-ADENYLATE Descriptor: HISTIDYL-ADENOSINE MONOPHOSPHATE, HISTIDYL-TRNA SYNTHETASE Authors: Arnez, J.G, Francklyn, C.S, Moras, D. Deposit date: 1997-05-09 Release date: 1997-12-17 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase. Proc.Natl.Acad.Sci.USA, 94, 1997
8UNT	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class I) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNS	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class H) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UO4	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class T) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (4 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNN	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class C) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UO3	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class S) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNM	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class B) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UO1	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class Q) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8W3V	Crystal structure of human WDR41 Descriptor: WD repeat-containing protein 41 Authors: Hutchinson, A, Dong, A, Li, Y, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) Deposit date: 2024-02-22 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of human WDR41 To be published
8UNW	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class L) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
7DH6	Crystal structure of PLRG1 Descriptor: CALCIUM ION, NICKEL (II) ION, Pleiotropic regulator 1, ... Authors: Wang, X, Xu, C. Deposit date: 2020-11-13 Release date: 2020-12-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.584 Å) Cite: Crystal structure of the WD40 domain of human PLRG1. Biochem.Biophys.Res.Commun., 534, 2021
8UNU	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class J) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNZ	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class O) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNR	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class G) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UO2	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class R) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNQ	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class F) Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2023-10-19 Release date: 2024-03-06 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
7CZ5	Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex Descriptor: CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M. Deposit date: 2020-09-07 Release date: 2020-11-18 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis for activation of the growth hormone-releasing hormone receptor. Nat Commun, 11, 2020
2I61	Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, CARBON DIOXIDE, ... Authors: Frolow, F, Gurevitz, M, Karbat, I, Turkov, M, Gordon, D. Deposit date: 2006-08-27 Release date: 2006-12-26 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.2 Å) Cite: X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity. J.Mol.Biol., 366, 2007
8SIY	Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome Descriptor: Histone H2A, Histone H2B, Histone H3.2, ... Authors: Bleichert, F, Ekundayo, B.E. Deposit date: 2023-04-17 Release date: 2023-08-02 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin. Embo J., 42, 2023

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