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8EIE
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BU of 8eie by Molmil
KRAS4b K117N 1-185 bound to GNP-Mg2+
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Betts, L, Rossman, K.L.
Deposit date:2022-09-14
Release date:2023-09-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:A crystallographic view of the fast-cycling KRAS mutant, K117N
To Be Published
8EZQ
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BU of 8ezq by Molmil
Cryo-EM structure of the S. cerevisiae guanine nucleotide exchange factor Gea2
Descriptor: ARF guanine-nucleotide exchange factor 2
Authors:Duan, H.D, Li, H.
Deposit date:2022-11-01
Release date:2023-11-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insight into an Arl1-ArfGEF complex involved in Golgi recruitment of a GRIP-domain golgin.
Nat Commun, 15, 2024
8EZJ
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BU of 8ezj by Molmil
Cryo-EM structure of the S. cerevisiae Arf-like protein Arl1 bound to the Arf guanine nucleotide exchange factor Gea2
Descriptor: ADP-ribosylation factor-like protein 1, ARF guanine-nucleotide exchange factor 2, GUANOSINE-5'-TRIPHOSPHATE
Authors:Duan, H.D, Li, H.
Deposit date:2022-11-01
Release date:2023-11-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insight into an Arl1-ArfGEF complex involved in Golgi recruitment of a GRIP-domain golgin.
Nat Commun, 15, 2024
8EXW
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BU of 8exw by Molmil
Drosophila melanogaster indirect flight muscle myosin II (subfragment-1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Isoform K of Myosin heavy chain, muscle, ...
Authors:Caldwell, J.T, Huxford, T, Bernstein, S.I, Stec, B.
Deposit date:2022-10-25
Release date:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Drosophila melanogaster indirect flight muscle myosin II (subfragment-1)
To Be Published
7OQC
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BU of 7oqc by Molmil
The U1 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A), Pre-mRNA-processing factor 39, ...
Authors:Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2021-06-03
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
7P6X
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BU of 7p6x by Molmil
Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Llorca, O, Serna, M, Fernandez-Leiro, R.
Deposit date:2021-07-18
Release date:2021-12-15
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.
Nucleic Acids Res., 50, 2022
7ON3
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BU of 7on3 by Molmil
SaFtsZ complexed with GDP (soak 10 mM EGTA)
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-25
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
8FO2
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BU of 8fo2 by Molmil
Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 monomer state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ...
Authors:Zhu, H, Sun, J.
Deposit date:2022-12-29
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2.
Science, 382, 2023
7OMP
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BU of 7omp by Molmil
SaFtsZ complexed with GDPPCP and Mg2+
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, MAGNESIUM ION, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-24
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7ON4
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BU of 7on4 by Molmil
SaFtsZ complexed with GDP (co-crystalization with 1mM EDTA)
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-25
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
8FO8
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BU of 8fo8 by Molmil
Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 dimer state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ...
Authors:Zhu, H, Sun, J.
Deposit date:2022-12-29
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2.
Science, 382, 2023
7OMQ
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BU of 7omq by Molmil
SaFtsZ complexed with GDPPCP and Mn2+
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, MANGANESE (II) ION, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-24
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7ON2
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BU of 7on2 by Molmil
SaFtsZ complexed with GDP (soaking in 10 mM CyDTA)
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-25
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OMJ
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BU of 7omj by Molmil
SaFtsZ complexed with GDPPCP
Descriptor: Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, POTASSIUM ION
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-24
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
8FO9
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BU of 8fo9 by Molmil
Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 tetramer state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ...
Authors:Zhu, H, Sun, J.
Deposit date:2022-12-30
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2.
Science, 382, 2023
8FMQ
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BU of 8fmq by Molmil
Complex structure of K210 deletion Troponin complex with alendronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.248 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMN
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BU of 8fmn by Molmil
Complex structure of K210 deletion Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-23
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMS
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BU of 8fms by Molmil
Complex structure of K210 deletion Troponin complex with neridronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.435 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMR
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BU of 8fmr by Molmil
Complex structure of K210 deletion Troponin complex with ibandronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.238 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMT
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BU of 8fmt by Molmil
Complex structure of TnnT-R205L Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMO
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BU of 8fmo by Molmil
Complex structure of K210 deletion Troponin complex with risedronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.612 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMP
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BU of 8fmp by Molmil
Complex structure of K210 deletion Troponin complex with pamidronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMM
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BU of 8fmm by Molmil
Complex structure of wild type Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-23
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.112 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8GVC
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BU of 8gvc by Molmil
The cryo-EM structure of hAE2 with bicarbonate
Descriptor: Anion exchange protein 2, BICARBONATE ION
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVF
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BU of 8gvf by Molmil
The outward-facing structure of hAE2 in basic pH
Descriptor: Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-15
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023

223532

數據於2024-08-07公開中

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