7KFU
 
 | | Cas6-RT-Cas1--Cas2 complex | | Descriptor: | Cas2, Cas6-RT-Cas1 | | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | | Deposit date: | 2020-10-14 | | Release date: | 2021-03-31 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
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7KFT
 | | Partial Cas6-RT-Cas1--Cas2 complex | | Descriptor: | Cas2, Cas6-RT-Cas1 | | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | | Deposit date: | 2020-10-14 | | Release date: | 2021-03-31 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
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6PPI
 | | Kaposi's sarcoma-associated herpesvirus (KSHV), C12 portal dodecamer structure | | Descriptor: | Portal protein | | Authors: | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | | Deposit date: | 2019-07-07 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV.
Cell, 178, 2019
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2M87
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7TAN
 | | Structure of VRK1 C-terminal tail bound to nucleosome core particle | | Descriptor: | Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, Histone H3.2, ... | | Authors: | Spangler, C.J, Budziszewski, G.R, McGinty, R.K. | | Deposit date: | 2021-12-21 | | Release date: | 2022-05-04 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.
Nucleic Acids Res., 50, 2022
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3QOQ
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7TN2
 | | Composite model of a Chd1-nucleosome complex in the nucleotide-free state derived from 2.3A and 2.7A Cryo-EM maps | | Descriptor: | Chromo domain-containing protein 1, DNA Lagging Strand, DNA Tracking Strand, ... | | Authors: | Nodelman, I.M, Bowman, G.D, Armache, J.-P. | | Deposit date: | 2022-01-20 | | Release date: | 2022-03-02 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state.
Nat.Struct.Mol.Biol., 29, 2022
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1XEW
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4KGC
 | | Nucleosome Core Particle Containing (ETA6-P-CYMENE)-(1, 2-ETHYLENEDIAMINE)-RUTHENIUM | | Descriptor: | (ethane-1,2-diamine-kappa~2~N,N')[(1,2,3,4,5,6-eta)-1-methyl-4-(propan-2-yl)cyclohexane-1,2,3,4,5,6-hexayl]ruthenium, DNA (145-mer), Histone H2A, ... | | Authors: | Adhireksan, Z, Davey, C.A. | | Deposit date: | 2013-04-29 | | Release date: | 2014-03-26 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity
Nat Commun, 5, 2014
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1XEX
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1JS5
 | | Solution Structure of dAAUAA DNA Bulge | | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*UP*AP*AP*GP*CP*TP*AP*CP*G)-3' | | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | | Deposit date: | 2001-08-16 | | Release date: | 2002-08-28 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges.
Nucleic Acids Res., 30, 2002
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1JS7
 | | Solution Structure of dAAUAA DNA Bulge | | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*UP*AP*AP*GP*CP*TP*AP*CP*G)-3' | | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | | Deposit date: | 2001-08-16 | | Release date: | 2002-06-19 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges.
Nucleic Acids Res., 30, 2002
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1YJM
 | | Crystal structure of the FHA domain of mouse polynucleotide kinase in complex with an XRCC4-derived phosphopeptide. | | Descriptor: | 12-mer peptide from DNA-repair protein XRCC4, Polynucleotide 5'-hydroxyl-kinase | | Authors: | Bernstein, N.K, Williams, R.S, Rakovszky, M.L, Cui, D, Green, R, Karimi-Busheri, F, Mani, R.S, Galicia, S, Koch, C.A, Cass, C.E, Durocher, D, Weinfeld, M, Glover, J.N.M. | | Deposit date: | 2005-01-14 | | Release date: | 2005-03-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
Mol.Cell, 17, 2005
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3AJK
 | | Crystal structure of d(CGCGGATf5UCGCG): 5-Formyluridine:Guanosine Base-pair in B-DNA with Hoechst33258 | | Descriptor: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 5'-D(*CP*GP*CP*GP*GP*AP*TP*(UFR)P*CP*GP*CP*G*)-3', MAGNESIUM ION | | Authors: | Tsunoda, M, Sakaue, T, Ueno, Y, Matsuda, A, Takenaka, A. | | Deposit date: | 2010-06-07 | | Release date: | 2011-04-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Insights into the structures of DNA damaged by hydroxyl radical: crystal structures of DNA duplexes containing 5-formyluracil
J Nucleic Acids, 2010, 2010
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2J07
 | | Thermus DNA photolyase with 8-HDF antenna chromophore | | Descriptor: | 8-HYDROXY-10-(D-RIBO-2,3,4,5-TETRAHYDROXYPENTYL)-5-DEAZAISOALLOXAZINE, CHLORIDE ION, DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, ... | | Authors: | Klar, T, Kaiser, G, Hennecke, U, Carell, T, Batschauer, A, Essen, L.-O. | | Deposit date: | 2006-08-01 | | Release date: | 2007-05-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus
Chembiochem, 7, 2006
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2J08
 | | Thermus DNA photolyase with 8-Iod-riboflavin antenna chromophore | | Descriptor: | 1-DEOXY-1-(8-IODO-7-METHYL-2,4-DIOXO-3,4-DIHYDROBENZO[G]PTERIDIN-10(2H)-YL)-D-RIBITOL, CHLORIDE ION, DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, ... | | Authors: | Klar, T, Kaiser, G, Hennecke, U, Carell, T, Batschauer, A, Essen, L.-O. | | Deposit date: | 2006-08-01 | | Release date: | 2007-05-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus
Chembiochem, 7, 2006
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4I7Y
 | | Crystal Structure of Human Alpha Thrombin in Complex with a 27-mer Aptamer Bound to Exosite II | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, DNA (27-MER), ... | | Authors: | Pica, A, Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | | Deposit date: | 2012-12-01 | | Release date: | 2013-10-16 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer.
Acta Crystallogr.,Sect.D, 69, 2013
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5GNW
 | | Crystal structure of Uracil DNA glycosylase-Uracil complex from Bradyrhizobium diazoefficiens. | | Descriptor: | Blr0248 protein, URACIL | | Authors: | Patil, V.V, Chembazhi, U.V, Varshney, U, Woo, E. | | Deposit date: | 2016-07-25 | | Release date: | 2017-06-14 | | Method: | X-RAY DIFFRACTION (2.869 Å) | | Cite: | Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity
Nucleic Acids Res., 45, 2017
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6FBU
 | | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate | | Descriptor: | ACETATE ION, DNA (5'-D(P*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3'), ... | | Authors: | Pomyalov, S, Lansky, S, Golan, G, Zharkov, D.O, Grollman, A.P, Shoham, G. | | Deposit date: | 2017-12-19 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate
To Be Published
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1S7O
 | | Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes | | Descriptor: | Hypothetical UPF0122 protein SPy1201/SpyM3_0842/SPs1042/spyM18_1152 | | Authors: | Oganesyan, V, Pufan, R, DeGiovanni, A, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | | Deposit date: | 2004-01-29 | | Release date: | 2004-06-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes.
Acta Crystallogr.,Sect.D, 60, 2004
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8W2R
 | | HIV-1 P5-IN intasome core | | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (5'-D(*AP*CP*TP*GP*CP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*CP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*GP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*GP*CP*A)-3'), ... | | Authors: | Li, M, Craigie, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-04-17 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro.
J.Mol.Biol., 436, 2024
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8W34
 | | HIV-1 intasome core assembled with wild-type integrase, 1F | | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (5'-D(*AP*CP*TP*GP*CP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*CP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*GP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*GP*CP*A)-3'), ... | | Authors: | Li, M, Craigie, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-04-17 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro.
J.Mol.Biol., 436, 2024
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2M00
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5W7Z
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3DTE
 | | Crystal structure of the IRRE protein, a central regulator of DNA damage repair in deinococcaceae | | Descriptor: | IrrE protein | | Authors: | Vujicic-Zagar, A, Dulermo, R, Le Gorrec, M, Vannier, F, Servant, P, Sommer, S, De Groot, A, Serre, L. | | Deposit date: | 2008-07-15 | | Release date: | 2009-02-10 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the IrrE protein, a central regulator of DNA damage repair in deinococcaceae
J.Mol.Biol., 386, 2009
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