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7V48
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Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V4A
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BU of 7v4a by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 1
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 1
To Be Published
7V4D
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BU of 7v4d by Molmil
Heparin-remodelled alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Heparin-remodelled alpha-synuclein fibrils
To Be Published
7V49
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BU of 7v49 by Molmil
Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
4R11
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BU of 4r11 by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
Descriptor: Cadherin-related hmr-1, IODIDE ION, Protein humpback-2
Authors:Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
7WMM
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BU of 7wmm by Molmil
alpha-synuclein fibril-F0502B complex
Descriptor: 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein
Authors:Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2022-01-15
Release date:2023-01-18
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:alpha-synuclein fibril-F0502B complex
To Be Published
4R10
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BU of 4r10 by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
Descriptor: 1,2-ETHANEDIOL, Cadherin-related hmr-1, Protein humpback-2, ...
Authors:Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
7VZO
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BU of 7vzo by Molmil
crystal structure of Domain 5-6 of filamin C from Scylla paramamosain
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Filamin C
Authors:He, X, Jin, T.
Deposit date:2021-11-16
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Scylla paramamosain Filamin C, Scy p 9.
J.Agric.Food Chem., 70, 2022
4C6A
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BU of 4c6a by Molmil
High Resolution Structure of the Nucleoside diphosphate kinase
Descriptor: DI(HYDROXYETHYL)ETHER, NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC
Authors:Priet, S, Ferron, F, Alvarez, K, Verron, M, Canard, B.
Deposit date:2013-09-18
Release date:2013-11-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity.
Antiviral Res., 117, 2015
4EDL
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BU of 4edl by Molmil
Crystal structure of beta-parvin CH2 domain
Descriptor: 1,2-ETHANEDIOL, Beta-parvin
Authors:Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J.
Deposit date:2012-03-27
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
J.Biol.Chem., 287, 2012
4DBQ
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BU of 4dbq by Molmil
MYOSIN VI D179Y (MD-INSERT2-CAM, DELTA-INSERT1) post-rigor state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ...
Authors:Pylypenko, O, Sweeney, H.L, Houdusse, A.
Deposit date:2012-01-16
Release date:2013-01-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating
To be Published
7XO2
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BU of 7xo2 by Molmil
Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2022-04-30
Release date:2022-11-30
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO1
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BU of 7xo1 by Molmil
Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2022-04-30
Release date:2022-11-30
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO0
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BU of 7xo0 by Molmil
Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2022-04-30
Release date:2022-11-30
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO3
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BU of 7xo3 by Molmil
Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2022-04-30
Release date:2022-11-30
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
4EDN
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BU of 4edn by Molmil
Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif
Descriptor: Beta-parvin, Paxillin, SULFATE ION
Authors:Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J.
Deposit date:2012-03-27
Release date:2012-08-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
J.Biol.Chem., 287, 2012
7XJX
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BU of 7xjx by Molmil
The cryo-EM structure of Fe3+ induced alpha-syn fibril.
Descriptor: Alpha-synuclein
Authors:Zhao, Q.Y, Tao, Y.Q, Zhao, K, Tao, Y.Q, Li, D.
Deposit date:2022-04-18
Release date:2023-01-18
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural Insights of Fe3+ Induced alpha-synuclein Fibrillation in Parkinson' Disease
J.Mol.Biol., 435, 2023
4EDM
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BU of 4edm by Molmil
Crystal structure of beta-parvin CH2 domain
Descriptor: 1,2-ETHANEDIOL, Beta-parvin
Authors:Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J.
Deposit date:2012-03-27
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
J.Biol.Chem., 287, 2012
9EMC
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BU of 9emc by Molmil
RUVBL1/2 in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RuvB-like 1, ...
Authors:Lopez-Perrote, A, Llorca, O, Garcia-Martin, C.
Deposit date:2024-03-11
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Mechanism of allosteric inhibition of RUVBL1-RUVBL2 by the small-molecule CB-6644
Cell Rep Phys Sci, 2024
4UW1
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BU of 4uw1 by Molmil
X-ray crystal structure of human TNKS in complex with a small molecule inhibitor
Descriptor: 1,2-ETHANEDIOL, 3-{4-[(dimethylamino)methyl]phenyl}-5-methoxyisoquinolin-1(2H)-one, GLYCEROL, ...
Authors:Oliver, A.W, Rajasekaran, M.B, Pearl, L.H.
Deposit date:2014-08-08
Release date:2015-07-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Design and Discovery of 3-Aryl-5-Substituted-Isoquinolin-1-Ones as Potent and Selective Tankyrase Inhibitors
Medchemcommm, 6, 2015
6YXO
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BU of 6yxo by Molmil
Structure of the N-terminal module of the human SWI/SNF-subunit BAF155/SMARCC1
Descriptor: SWI/SNF complex subunit SMARCC1
Authors:Allen, M.D, Bycroft, M, Zinzalla, G.
Deposit date:2020-05-03
Release date:2021-04-21
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site.
Commun Biol, 4, 2021
6YXP
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BU of 6yxp by Molmil
Higher resolution structure of the N-terminal module of the human SWI/SNF-subunit BAF155/SMARCC1
Descriptor: SWI/SNF complex subunit SMARCC1
Authors:Allen, M.D, Bycroft, M, Zinzalla, G.
Deposit date:2020-05-03
Release date:2021-04-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site.
Commun Biol, 4, 2021
6QI9
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BU of 6qi9 by Molmil
Truncated human R2TP complex, structure 4 (ADP-empty)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O.
Deposit date:2019-01-18
Release date:2019-05-15
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.63 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
6A62
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BU of 6a62 by Molmil
Placental protein 13/galectin-13 variant R53HH57RD33G with Lactose
Descriptor: Galactoside-binding soluble lectin 13, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Su, J.
Deposit date:2018-06-26
Release date:2018-12-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose
Biosci. Rep., 38, 2018
6QI8
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BU of 6qi8 by Molmil
Truncated human R2TP complex, structure 3 (ADP-filled)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O.
Deposit date:2019-01-18
Release date:2019-04-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019

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數據於2024-07-10公開中

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