1SMI
 
 | | A single mutation of P450 BM3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme | | Descriptor: | Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Joyce, M.G, Girvan, H.M, Munro, A.W, Leys, D. | | Deposit date: | 2004-03-09 | | Release date: | 2004-06-08 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Single Mutation in Cytochrome P450 BM3 Induces the Conformational Rearrangement Seen upon Substrate Binding in the Wild-type Enzyme
J.Biol.Chem., 279, 2004
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1G0U
 | | A GATED CHANNEL INTO THE PROTEASOME CORE PARTICLE | | Descriptor: | MAGNESIUM ION, PROTEASOME COMPONENT C1, PROTEASOME COMPONENT C11, ... | | Authors: | Groll, M, Bajorek, M, Kohler, A, Moroder, L, Rubin, D.M, Huber, R, Glickman, M.H, Finley, D. | | Deposit date: | 2000-10-09 | | Release date: | 2000-11-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A gated channel into the proteasome core particle.
Nat.Struct.Biol., 7, 2000
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2KQG
 | | A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics | | Descriptor: | 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*CP*GP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3', POTASSIUM ION | | Authors: | Hsu, S.-T.D, Varnai, P, Bugaut, A, Reszka, A.P, Neidle, S, Balasubramanian, S. | | Deposit date: | 2009-11-05 | | Release date: | 2009-11-24 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics
J.Am.Chem.Soc., 131, 2009
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3RTR
 | | A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases | | Descriptor: | Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION | | Authors: | Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A. | | Deposit date: | 2011-05-03 | | Release date: | 2011-07-20 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.21 Å) | | Cite: | A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
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2GB1
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2NVJ
 | | NMR structures of transmembrane segment from subunit a from the yeast proton V-ATPase | | Descriptor: | 25mer peptide from Vacuolar ATP synthase subunit a, vacuolar isoform | | Authors: | Hemminga, M.A, van Mierlo, C.P, Wechselberger, R, de Jong, E.R, Duarte, A.M. | | Deposit date: | 2006-11-13 | | Release date: | 2007-10-02 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Segment TM7 from the cytoplasmic hemi-channel from V(O)-H(+)-V-ATPase includes a flexible region that has a potential role in proton translocation
Biochim.Biophys.Acta, 1768, 2007
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2F8O
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2O7N
 | | CD11A (LFA1) I-domain complexed with 7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile | | Descriptor: | 7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile, Integrin alpha-L | | Authors: | Sheriff, S. | | Deposit date: | 2006-12-11 | | Release date: | 2007-03-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold.
Bioorg.Med.Chem.Lett., 17, 2007
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2EYR
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2CHR
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2J9Q
 | | A novel conformation for the TPR domain of pex5p | | Descriptor: | PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR, STRONTIUM ION | | Authors: | Stanley, W.A, Wilmanns, M, Kursula, P. | | Deposit date: | 2006-11-15 | | Release date: | 2007-04-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | A Previously Unobserved Conformation for the Human Pex5P Receptor Suggests Roles for Intrinsic Flexibility and Rigid Domain Motions in Ligand Binding
Bmc Struct.Biol., 7, 2007
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2JAB
 | | A designed ankyrin repeat protein evolved to picomolar affinity to Her2 | | Descriptor: | H10-2-G3 | | Authors: | Zahnd, C, Wyler, E, Schwenk, J.M, Steiner, D, Lawrence, M.C, McKern, N.M, Pecorari, F, Ward, C.W, Joos, T.O, Pluckthun, A. | | Deposit date: | 2006-11-27 | | Release date: | 2007-05-08 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2
J.Mol.Biol., 369, 2007
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2K0E
 | | A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction | | Descriptor: | CALCIUM ION, Calmodulin | | Authors: | Gsponer, J, Christodoulou, J, Cavalli, A, Bui, J.M, Richter, B, Dobson, C.M, Vendruscolo, M. | | Deposit date: | 2008-02-02 | | Release date: | 2008-06-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
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2EYS
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2EYT
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2LFM
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2JB4
 | | Isopenicillin N synthase with a 2-thiabicycloheptan-6-one product analogue | | Descriptor: | (1S,4S,5S,7R)-7-{[(5S)-5-AMINO-5-CARBOXYPENTANOYL]AMINO}-3,3-DIMETHYL-6-OXO-2-THIABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID, FE (III) ION, GLYCEROL, ... | | Authors: | Stewart, A.C, Clifton, I.J, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. | | Deposit date: | 2006-12-01 | | Release date: | 2007-10-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | A Cyclobutanone Analogue Mimics Penicillin in Binding to Isopenicillin N Synthase.
Chembiochem, 8, 2007
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2IBM
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2KJI
 | | A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor | | Descriptor: | Probable insulin-like peptide beta-type 5 | | Authors: | Hua, Q.X, Nakarawa, S.H, Wilken, R, Ramos, R.R, Jia, W.H, Bass, J, Weiss, M.A. | | Deposit date: | 2009-05-28 | | Release date: | 2009-06-16 | | Last modified: | 2019-09-18 | | Method: | SOLUTION NMR | | Cite: | A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor.
Genes Dev., 17, 2003
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2KQO
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2MC6
 | | A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement | | Descriptor: | DNA-directed RNA polymerase subunit beta', RNA polymerase inhibitor p7 | | Authors: | Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S. | | Deposit date: | 2013-08-15 | | Release date: | 2014-04-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement.
Nucleic Acids Res., 42, 2014
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2MC5
 | | A bacteriophage transcription regulator inhibits bacterial transcription initiation by -factor displacement | | Descriptor: | 45L | | Authors: | Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S. | | Deposit date: | 2013-08-14 | | Release date: | 2014-03-26 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement.
Nucleic Acids Res., 42, 2014
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1CON
 | | THE REFINED STRUCTURE OF CADMIUM SUBSTITUTED CONCANAVALIN A AT 2.0 ANGSTROMS RESOLUTION | | Descriptor: | CADMIUM ION, CALCIUM ION, CONCANAVALIN A | | Authors: | Naismith, J.H, Habash, J, Harrop, S.J, Helliwell, J.R, Hunter, W.N, Kalb(Gilboa), A.J, Yariv, J, Wan, T.C.M, Weisgerber, S. | | Deposit date: | 1993-03-16 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Refined structure of cadmium-substituted concanavalin A at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
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1CJP
 | | CONCANAVALIN A COMPLEX WITH 4'-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE | | Descriptor: | 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOSE, CALCIUM ION, CONCANAVALIN A, ... | | Authors: | Hamodrakas, S.J, Kanellopoulos, P.N, Tucker, P.A. | | Deposit date: | 1996-10-03 | | Release date: | 1997-10-15 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | The crystal structure of the complex of concanavalin A with 4'-methylumbelliferyl-alpha-D-glucopyranoside.
J.Struct.Biol., 118, 1997
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1D6H
 | | CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA) | | Descriptor: | CHALCONE SYNTHASE, COENZYME A, SULFATE ION | | Authors: | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | | Deposit date: | 1999-10-13 | | Release date: | 2000-02-03 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
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