PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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4XAX	Crystal structure of Thermus thermophilus CarD in complex with the Thermus aquaticus RNA polymerase beta1 domain Descriptor: 1,2-ETHANEDIOL, CarD, DNA-directed RNA polymerase subunit beta domain 1 Authors: Chen, J, Bae, B, Campbell, E.A, Darst, S.A. Deposit date: 2014-12-15 Release date: 2015-09-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.404 Å) Cite: CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
5TJG	Thermus aquaticus delta1.1-sigmaA holoenzyme/downstream-fork promoter complex with an open clamp Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*A)-3'), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Darst, S.A, Bae, B. Deposit date: 2016-10-04 Release date: 2017-06-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: RNA polymerase motions during promoter melting. Science, 356, 2017
5N9G	TFIIIB -TBP/Brf2/DNA and SANT domain of Bdp1- Descriptor: DNA/RNA (25-MER), DNA/RNA (27-MER), SODIUM ION, ... Authors: Gouge, J, Vannini, A, Guthertz, N. Deposit date: 2017-02-24 Release date: 2017-06-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation. Nat Commun, 8, 2017
5JNB	structure of GLD-2/RNP-8 complex Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Poly(A) RNA polymerase gld-2, ... Authors: Nakel, K, Bonneau, F, Basquin, C, Eckmann, C.R, Conti, E. Deposit date: 2016-04-29 Release date: 2016-06-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.486 Å) Cite: Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity. Rna, 22, 2016
8ABY	RNA polymerase bound to purified in vitro transcribed regulatory RNA putL - pause prone, closed clamp state Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Dey, S, Weixlbaumer, A. Deposit date: 2022-07-05 Release date: 2022-10-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8AC0	RNA polymerase at U-rich pause bound to regulatory RNA putL - active, closed clamp state Descriptor: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ... Authors: Weixlbaumer, A, Dey, S. Deposit date: 2022-07-05 Release date: 2022-10-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8AD1	RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Dey, S, Weixlbaumer, A. Deposit date: 2022-07-07 Release date: 2022-10-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8ACP	RNA polymerase at U-rich pause bound to regulatory RNA putL - inactive, open clamp state Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Dey, S, Weixlbaumer, A. Deposit date: 2022-07-06 Release date: 2022-10-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8ABZ	RNA polymerase at U-rich pause bound to non-regulatory RNA - pause prone, closed clamp state Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Dey, S, Weixlbaumer, A. Deposit date: 2022-07-05 Release date: 2022-10-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8AC1	RNA polymerase at U-rich pause bound to non-regulatory RNA - inactive, open clamp state Descriptor: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ... Authors: Dey, S, Weixlbaumer, A. Deposit date: 2022-07-05 Release date: 2022-10-26 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4.06 Å) Cite: Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
4PZ6	PCE1 guanylyltransferase bound to SER2/SER5 phosphorylated RNA pol II CTD Descriptor: DNA-directed RNA polymerase II subunit rpb1, GUANOSINE, mRNA-capping enzyme subunit alpha Authors: Doamekpor, S.K, Lima, C.D. Deposit date: 2014-03-28 Release date: 2014-06-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.406 Å) Cite: How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes Dev., 28, 2014
7PZP	Mitochondrial DNA dependent RNA polymerase homodimer. Descriptor: DNA-directed RNA polymerase, mitochondrial Authors: Das, H, Hallberg, B.M. Deposit date: 2021-10-13 Release date: 2022-09-28 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022
6DT8	Bacteriophage N4 RNA polymerase II elongation complex 1 Descriptor: DNA (5'-D(P*AP*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*UP*GP*G)-3'), RNAP1, ... Authors: Molodtsov, V, Murakami, K.S. Deposit date: 2018-06-15 Release date: 2018-07-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
6DTA	Bacteriophage N4 RNA polymerase II elongation complex 2 Descriptor: DNA (5'-D(P*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Molodtsov, V, Murakami, K.S. Deposit date: 2018-06-15 Release date: 2018-07-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.694 Å) Cite: Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
2WHO	CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR Descriptor: 2-(3-bromophenyl)-6-[(2-hydroxyethyl)amino]-1h-benzo[de]isoquinoline-1,3(2h)-dione, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Di Marco, S. Deposit date: 2009-05-05 Release date: 2009-08-11 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors. J. Med. Chem., 52, 2009
6DT7	Bacteriophage N4 RNA polymerase II and DNA complex Descriptor: DNA (5'-D(P*CP*CP*AP*CP*CP*TP*GP*CP*A)-3'), RNAP1, RNAP2 Authors: Molodtsov, V, Murakami, K.S. Deposit date: 2018-06-15 Release date: 2018-07-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
5H0R	RNA dependent RNA polymerase ,vp4,dsRNA Descriptor: RNA (42-MER), RNA-dependent RNA polymerase, VP4 protein Authors: Li, X, Zhou, N, Chen, W, Zhu, B, Wang, X, Xu, B, Wang, J, Liu, H, Cheng, L. Deposit date: 2016-10-06 Release date: 2017-01-25 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Near-Atomic Resolution Structure Determination of a Cypovirus Capsid and Polymerase Complex Using Cryo-EM at 200kV J. Mol. Biol., 429, 2017
4KI2	Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA Descriptor: DNA (5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3'), POTASSIUM ION, RNA polymerase sigma factor Authors: Feklistov, A, Darst, S.A. Deposit date: 2013-05-01 Release date: 2013-09-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Crystallographic analysis of an RNA polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes. Acta Crystallogr.,Sect.F, 69, 2013
3P8B	X-ray crystal structure of Pyrococcus furiosus transcription elongation factor Spt4/5 Descriptor: BETA-MERCAPTOETHANOL, DNA-directed RNA polymerase, subunit e'', ... Authors: Murakami, K.S, Klein, B.J. Deposit date: 2010-10-13 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: RNA polymerase and transcription elongation factor Spt4/5 complex structure. Proc.Natl.Acad.Sci.USA, 108, 2011
8IIB	Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546) Descriptor: CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ... Authors: Fang, X, Lu, G, Hou, C, Gong, P. Deposit date: 2023-02-24 Release date: 2023-06-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding. Virol Sin, 38, 2023
7Y7P	QDE-1 in complex with RNA template, RNA primer and AMPNPP Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Cui, R.X, Gan, J.H, Ma, J.B. Deposit date: 2022-06-22 Release date: 2022-09-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1. Nucleic Acids Res., 50, 2022
7Y7Q	QDE-1 in complex with RNA template, RNA primer and 3'-dGTP Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Cui, R.X, Gan, J.H, Ma, J.B. Deposit date: 2022-06-22 Release date: 2022-09-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1. Nucleic Acids Res., 50, 2022
3JA4	RNA-dependent RNA polymerases of transcribing cypoviruses Descriptor: RNA-dependent RNA polymerase Authors: Liu, H, Cheng, L. Deposit date: 2015-04-20 Release date: 2015-10-28 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus. Science, 349, 2015
7Y7R	QDE-1 in complex with DNA template, RNA primer and 3'-dGTP Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*AP*AP*CP*TP*AP*CP*CP*GP*TP*CP*GP*GP*A)-3'), ... Authors: Cui, R.X, Gan, J.H, Ma, J.B. Deposit date: 2022-06-22 Release date: 2022-09-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1. Nucleic Acids Res., 50, 2022
7Y7S	QDE-1 in complex with DNA template, RNA primer and AMPNPP Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Cui, R.X, Gan, J.H, Ma, J.B. Deposit date: 2022-06-22 Release date: 2022-09-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1. Nucleic Acids Res., 50, 2022

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