4ERC
 
 | | Structure of VHZ bound to metavanadate | | Descriptor: | Dual specificity protein phosphatase 23, oxido(dioxo)vanadium | | Authors: | Vyacheslav, K, Alvan, C.H, Sean, J.J. | | Deposit date: | 2012-04-19 | | Release date: | 2012-12-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | New Aspects of the Phosphatase VHZ Revealed by a High-Resolution Structure with Vanadate and Substrate Screening.
Biochemistry, 51, 2012
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4HRF
 | | Atomic structure of DUSP26 | | Descriptor: | Dual specificity protein phosphatase 26 | | Authors: | Lokareddy, R.K, Bhardwaj, A, Cingolani, G. | | Deposit date: | 2012-10-27 | | Release date: | 2013-01-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase.
Biochemistry, 52, 2013
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4JMJ
 | | Structure of dusp11 | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | | Authors: | Jeong, D.G, Kim, S.J, Ryu, S.E. | | Deposit date: | 2013-03-14 | | Release date: | 2014-02-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.382 Å) | | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases.
Acta Crystallogr.,Sect.D, 70, 2014
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4JMK
 | | Structure of dusp8 | | Descriptor: | Dual specificity protein phosphatase 8, SULFATE ION | | Authors: | Jeong, D.G, Kim, S.J, Ryu, S.E. | | Deposit date: | 2013-03-14 | | Release date: | 2014-02-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases.
Acta Crystallogr.,Sect.D, 70, 2014
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4JNB
 | | Crystal structure of the Catalytic Domain of Human DUSP12 | | Descriptor: | Dual specificity protein phosphatase 12, SULFATE ION | | Authors: | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | | Deposit date: | 2013-03-15 | | Release date: | 2014-03-26 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases.
Acta Crystallogr.,Sect.D, 70, 2014
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4KI9
 | | Crystal structure of the catalytic domain of human DUSP12 at 2.0 A resolution | | Descriptor: | Dual specificity protein phosphatase 12, PHOSPHATE ION | | Authors: | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | | Deposit date: | 2013-05-02 | | Release date: | 2014-02-26 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases
Acta Crystallogr.,Sect.D, 70, 2014
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4KYQ
 | | Structure of a product bound plant phosphatase | | Descriptor: | CITRATE ANION, Phosphoglucan phosphatase LSF2, chloroplastic | | Authors: | Meekins, D.A, Guo, H.-F, Husodo, S, Paasch, B.C, Bridges, T.M, Santelia, D, Kotting, O, Vander Kooi, C.W, Gentry, M.S. | | Deposit date: | 2013-05-29 | | Release date: | 2013-07-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structure of the Arabidopsis Glucan Phosphatase LIKE SEX FOUR2 Reveals a Unique Mechanism for Starch Dephosphorylation.
Plant Cell, 25, 2013
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4KYR
 | | Structure of a product bound plant phosphatase | | Descriptor: | PHOSPHATE ION, Phosphoglucan phosphatase LSF2, chloroplastic, ... | | Authors: | Meekins, D.A, Guo, H.-F, Husodo, S, Paasch, B.C, Bridges, T.M, Santelia, D, Kotting, O, Vander Kooi, C.W, Gentry, M.S. | | Deposit date: | 2013-05-29 | | Release date: | 2013-07-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the Arabidopsis Glucan Phosphatase LIKE SEX FOUR2 Reveals a Unique Mechanism for Starch Dephosphorylation.
Plant Cell, 25, 2013
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4MBB
 | | Cubic crystal form of PIR1 dual specificity phosphatase core | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | | Authors: | Sankhala, R.S, Lokareddy, R.K, Cingolani, G. | | Deposit date: | 2013-08-19 | | Release date: | 2013-12-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.849 Å) | | Cite: | Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
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4NYH
 | | Orthorhombic crystal form of pir1 dual specificity phosphatase core | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | | Authors: | Sankhala, R.S, Lokareddy, R.K, Cingolani, G. | | Deposit date: | 2013-12-10 | | Release date: | 2014-01-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
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4PYH
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4R30
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4RKK
 | | Structure of a product bound phosphatase | | Descriptor: | Laforin, PHOSPHATE ION, alpha-D-glucopyranose, ... | | Authors: | Vander Kooi, C.W. | | Deposit date: | 2014-10-13 | | Release date: | 2015-01-07 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease.
Mol.Cell, 57, 2015
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4WOH
 | | Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with 4-nitrophenolphosphate | | Descriptor: | 1,2-ETHANEDIOL, 4-NITROPHENYL PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Lountos, G.T, Cherry, S, Tropea, J.E, Waugh, D.S. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate.
Acta Crystallogr.,Sect.F, 71, 2015
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4Y2E
 | | Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (C232S) | | Descriptor: | Dual specificity protein phosphatase 7, PHOSPHATE ION | | Authors: | Lountos, G.T, Austin, B.P, Tropea, J.E, Waugh, D.S. | | Deposit date: | 2015-02-09 | | Release date: | 2015-06-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Structure of human dual-specificity phosphatase 7, a potential cancer drug target.
Acta Crystallogr.,Sect.F, 71, 2015
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4YR8
 | | Crystal structure of JNK in complex with a regulator protein | | Descriptor: | CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8 | | Authors: | Liu, X, Wang, J, Wu, J.W, Wang, Z.X. | | Deposit date: | 2015-03-14 | | Release date: | 2016-03-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation.
Nat Commun, 7, 2016
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5BX1
 | | Crystal Structure of PRL-1 complex with compound analogy 3 | | Descriptor: | 3-(5,6-dimethyl-2H-isoindol-2-yl)-N'-[(E)-furan-2-ylmethylidene]benzohydrazide, Protein tyrosine phosphatase type IVA 1, SULFATE ION | | Authors: | Liu, S, Bai, Y, Zhang, Z. | | Deposit date: | 2015-06-08 | | Release date: | 2016-12-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of PRL-1 complex with compound analogy 3
To Be Published
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5GTJ
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5LXQ
 | | Structure of PRL-1 in complex with the Bateman domain of CNNM2 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1, ... | | Authors: | GIMENEZ-Mascarell, P, Oyenarte, I, Hardy, S, Breiderhoff, T, Stuiver, M, Kostantin, E, Diercks, T, Pey, A.L, Ereno-ORBEA, J, Martinez-Chantar, M.L, Khalaf-Nazzal, R, Claverie-Martin, F, Muller, D, Tremblay, M, Martinez-Cruz, L.A. | | Deposit date: | 2016-09-22 | | Release date: | 2016-12-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.335 Å) | | Cite: | Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
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5M43
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5MMZ
 | | Structure of PRL-1 in complex with the Bateman domain of CNNM2 | | Descriptor: | Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1 | | Authors: | Gimenez-Mascarell, P, Oyenarte, I, Hardy, S, Breiderhoff, T, Stuiver, M, Kostantin, E, Diercks, T, Pey, A.L, Ereno-Orbea, J, Martinez-Chantar, M.L, Khalaf-Nazzal, R, Claverie-Martin, F, Muller, D, Tremblay, M.L, Martinez-Cruz, L.A. | | Deposit date: | 2016-12-12 | | Release date: | 2016-12-21 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
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5NCR
 | | OH1 from the Orf virus: a tyrosine phosphatase that displays distinct structural features and triple substrate specificity | | Descriptor: | PHOSPHATE ION, SULFATE ION, tyrosine phosphatase | | Authors: | Segovia, D, Haouz, A, Berois, M, Villarino, A, Andre-Leroux, G. | | Deposit date: | 2017-03-06 | | Release date: | 2017-08-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity.
J. Mol. Biol., 429, 2017
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5XJV
 | | Two intermediate states of conformation switch in dual specificity phosphatase 13a | | Descriptor: | Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION | | Authors: | Wei, C.H, Min, H.G, Chun, H.J, Ryu, S.E. | | Deposit date: | 2017-05-04 | | Release date: | 2018-04-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Two intermediate states of the conformational switch in dual specificity phosphatase 13a
Pharmacol. Res., 128, 2018
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5XW4
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5XW5
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