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3VAF
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BU of 3vaf by Molmil
Structure of U2AF65 variant with BrU3 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*(BRU)P*UP*UP*U)-3', GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3VAM
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BU of 3vam by Molmil
Structure of U2AF65 variant with BrU5C2 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*CP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3VAJ
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BU of 3vaj by Molmil
Structure of U2AF65 variant with BrU5C6 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*CP*U)-3'), GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3VAI
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BU of 3vai by Molmil
Structure of U2AF65 variant with BrU3C5 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*UP*CP*UP*U)-3', GLYCEROL, ...
Authors:Jenkins, J.L, Frato, K.H, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
7S3B
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BU of 7s3b by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide
Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3C
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BU of 7s3c by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Glasser, E, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3A
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BU of 7s3a by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
8ONS
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BU of 8ons by Molmil
TAF15 amyloid fold in atypical FTLD - Individual 1
Descriptor: TATA-binding protein-associated factor 2N
Authors:Tetter, S, Ryskeldi-Falcon, B.
Deposit date:2023-04-03
Release date:2023-12-06
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (1.97 Å)
Cite:TAF15 amyloid filaments in frontotemporal lobar degeneration.
Nature, 625, 2024
7JLY
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BU of 7jly by Molmil
Crystal Structure of RNA Binding Protein PG1
Descriptor: ACETATE ION, CALCIUM ION, RNA-binding protein
Authors:Musayev, F.N, Scarsdale, J.N, Belvin, B.R, Lewis, J.P.
Deposit date:2020-07-30
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:High Resolution Structure of RNA Binding Protein PG1
To be published
8JY0
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BU of 8jy0 by Molmil
Crystal structure of RhoBAST complexed with TMR-DN
Descriptor: 2,4-dinitroaniline, 5-aminocarbonyl-2-[3-(dimethylamino)-6-dimethylazaniumylidene-xanthen-9-yl]benzoate, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Zhang, Y, Xiao, Y, Xu, Z, Fang, X.
Deposit date:2023-07-02
Release date:2024-05-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST.
Nat Commun, 15, 2024
8P25
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BU of 8p25 by Molmil
Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box
Descriptor: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1
Authors:Hipp, C, Sattler, M.
Deposit date:2023-05-14
Release date:2023-07-26
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
7LHX
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BU of 7lhx by Molmil
Human U1A protein with F37M and F77M mutations for improved phasing
Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ...
Authors:Jenkins, J.L, Lippa, G.M, Wedekind, J.E.
Deposit date:2021-01-26
Release date:2021-03-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing
Crystals, 11, 2021
6DCL
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BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
Authors:Kooshapur, H, Sattler, M.
Deposit date:2018-05-07
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
6DG0
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BU of 6dg0 by Molmil
MEC-8 C-terminal RRM domain bound to AGCACA
Descriptor: DNA (5'-D(*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein
Authors:Mackereth, C.D, Soufari, H.
Deposit date:2018-05-16
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.457 Å)
Cite:Structure of MEC-8 RRM2 in complex with AGCACA
To Be Published
6DG1
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BU of 6dg1 by Molmil
NMR structure of the second qRRM2 domain of human hnRNP H
Descriptor: qRRM2 domain of Heterogeneous nuclear ribonucleoprotein H2
Authors:Srinivasa, R.P.
Deposit date:2018-05-16
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H.
J. Am. Chem. Soc., 2018
6E4N
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BU of 6e4n by Molmil
Structure of the T. brucei TbRGG2 RRM domain: apo R3 crystal form
Descriptor: RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6E4O
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BU of 6e4o by Molmil
Structure of apo T. brucei RRM: P4(1)2(1)2 form
Descriptor: RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6E4P
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BU of 6e4p by Molmil
Structure of the T. brucei RRM domain in complex with RNA
Descriptor: RNA (5'-R(P*UP*UP*UP*U)-3'), RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6ELD
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BU of 6eld by Molmil
Crystal structure of TIA-1 RRM1 in complex with U1C
Descriptor: Nucleolysin TIA-1 isoform p40,U1 small nuclear ribonucleoprotein C
Authors:Jagtap, P.K.A, Sattler, M.
Deposit date:2017-09-28
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.485 Å)
Cite:Crystal structure of TIA-1 RRM1 in complex with U1C
To Be Published
1AUD
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BU of 1aud by Molmil
U1A-UTRRNA, NMR, 31 STRUCTURES
Descriptor: RNA 3UTR, U1A 102
Authors:Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G.
Deposit date:1997-08-22
Release date:1998-02-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J., 16, 1997
1JMT
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BU of 1jmt by Molmil
X-ray Structure of a Core U2AF65/U2AF35 Heterodimer
Descriptor: HEXANE-1,6-DIOL, SPLICING FACTOR U2AF 35 KDA SUBUNIT, SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Kielkopf, C.L, Rodionova, N.A, Green, M.R, Burley, S.K.
Deposit date:2001-07-19
Release date:2001-09-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.
Cell(Cambridge,Mass.), 106, 2001
1CVJ
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BU of 1cvj by Molmil
X-RAY CRYSTAL STRUCTURE OF THE POLY(A)-BINDING PROTEIN IN COMPLEX WITH POLYADENYLATE RNA
Descriptor: 5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', ADENOSINE MONOPHOSPHATE, POLYADENYLATE BINDING PROTEIN 1
Authors:Deo, R.C, Bonanno, J.B, Sonenberg, N, Burley, S.K.
Deposit date:1999-08-23
Release date:1999-10-04
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Recognition of polyadenylate RNA by the poly(A)-binding protein.
Cell(Cambridge,Mass.), 98, 1999
1D9A
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BU of 1d9a by Molmil
SOLUTION STRUCTURE OF THE SECOND RNA-BINDING DOMAIN (RBD2) OF HU ANTIGEN C (HUC)
Descriptor: HU ANTIGEN C
Authors:Inoue, M, Muto, Y, Sakamoto, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-10-26
Release date:2000-04-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C.
Nucleic Acids Res., 28, 2000
1D8Z
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BU of 1d8z by Molmil
SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN (RBD1) OF HU ANTIGEN C (HUC)
Descriptor: HU ANTIGEN C
Authors:Inoue, M, Muto, Y, Sakamoto, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-10-26
Release date:2000-04-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C.
Nucleic Acids Res., 28, 2000
1L3K
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BU of 1l3k by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
Descriptor: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
Authors:Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M.
Deposit date:2002-02-27
Release date:2002-04-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002

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數據於2024-07-17公開中

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