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6LTJ
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BU of 6ltj by Molmil
Structure of nucleosome-bound human BAF complex
Descriptor: AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ...
Authors:He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y.
Deposit date:2020-01-22
Release date:2020-02-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of nucleosome-bound human BAF complex.
Science, 367, 2020
5JA4
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BU of 5ja4 by Molmil
Crystal structure of human TONSL and MCM2 HBDs binding to a histone H3-H4 tetramer
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA replication licensing factor MCM2, GLYCEROL, ...
Authors:Huang, H, Patel, D.
Deposit date:2016-04-11
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.424 Å)
Cite:H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex.
Nature, 534, 2016
7V1M
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BU of 7v1m by Molmil
Structural basis for the co-chaperone relationship of sNASP and ASF1b
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Bao, H, Huang, H.
Deposit date:2021-08-04
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022
8JH2
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BU of 8jh2 by Molmil
RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH3
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BU of 8jh3 by Molmil
RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH4
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BU of 8jh4 by Molmil
RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
6A5L
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BU of 6a5l by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA
Descriptor: DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-24
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5R
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BU of 6a5r by Molmil
RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5T
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BU of 6a5t by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5P
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BU of 6a5p by Molmil
RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5U
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BU of 6a5u by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation
Descriptor: DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
3MUL
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BU of 3mul by Molmil
Crystal structure of Brd4 bromodomain 1 with butyrylated histone H3-K(buty)14
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Peptide of Histone H3.3
Authors:Vollmuth, F, Geyer, M.
Deposit date:2010-05-03
Release date:2010-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
Angew.Chem.Int.Ed.Engl., 49, 2010
3MUK
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BU of 3muk by Molmil
Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, peptide of Histone H3.3
Authors:Vollmuth, F, Geyer, M.
Deposit date:2010-05-03
Release date:2010-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
Angew.Chem.Int.Ed.Engl., 49, 2010
3QLA
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BU of 3qla by Molmil
Hexagonal complex structure of ATRX ADD bound to H3K9me3 peptide
Descriptor: POTASSIUM ION, Transcriptional regulator ATRX, ZINC ION, ...
Authors:Xiang, B, Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QL9
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BU of 3ql9 by Molmil
Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide
Descriptor: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
Authors:Xiang, B, Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QLC
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BU of 3qlc by Molmil
Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide
Descriptor: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
Authors:Li, H, Patel, D.J.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
6IR9
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BU of 6ir9 by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2018-11-12
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6INQ
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BU of 6inq by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position)
Descriptor: DNA (198-MER), DNA (31-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-10-26
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6J50
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BU of 6j50 by Molmil
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome (tilted conformation)
Descriptor: DNA (198-MER), DNA (41-MER), DNA-directed RNA polymerase subunit, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6HGT
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BU of 6hgt by Molmil
Crystal structure of human KDM4A complexed with co-substrate analog NOG and histone H3 peptide with K9R mutation
Descriptor: Histone H3.3, Lysine-specific demethylase 4A, N-OXALYLGLYCINE, ...
Authors:Maw, J, Le Bihan, Y.V, van Montfort, R.L.M.
Deposit date:2018-08-23
Release date:2019-09-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure-based design of selective, histone substrate-based inhibitors of histone lysine demethylases 4 (KDM4) subfamily
To be published
6J4W
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BU of 6j4w by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-5) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6J4X
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BU of 6j4x by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1A)
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6J4Z
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BU of 6j4z by Molmil
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6J51
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BU of 6j51 by Molmil
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome, weak Elf1 (+1 position)
Descriptor: DNA (198-MER), DNA (36-MER), DNA-directed RNA polymerase subunit, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6J4Y
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BU of 6j4y by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1B)
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019

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數據於2024-10-16公開中

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