2G5M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2g5m by Molmil](/molmil-images/mine/2g5m) | Spinophilin PDZ domain | Descriptor: | Neurabin-2 | Authors: | Kelker, M.S, Peti, W. | Deposit date: | 2006-02-23 | Release date: | 2007-01-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis for spinophilin-neurabin receptor interaction. Biochemistry, 46, 2007
|
|
1NF3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nf3 by Molmil](/molmil-images/mine/1nf3) | Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 | Descriptor: | G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ... | Authors: | Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R. | Deposit date: | 2002-12-12 | Release date: | 2003-03-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 Embo J., 22, 2003
|
|
6V69
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v69 by Molmil](/molmil-images/mine/6v69) | Structures of GCP4 and GCP5 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 4, Gamma-tubulin complex component 5 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
|
|
6V6C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v6c by Molmil](/molmil-images/mine/6v6c) | Structure of GCP6 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 6 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
|
|
1R6J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1r6j by Molmil](/molmil-images/mine/1r6j) | Ultrahigh resolution Crystal Structure of syntenin PDZ2 | Descriptor: | CHLORIDE ION, Syntenin 1 | Authors: | Kang, B.S, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2003-10-15 | Release date: | 2004-05-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (0.73 Å) | Cite: | The PDZ2 domain of syntenin at ultra-high resolution: bridging the gap between small molecule and macromolecular crystal chemistry J.Mol.Biol., 338, 2004
|
|
1KZG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kzg by Molmil](/molmil-images/mine/1kzg) | DbsCdc42(Y889F) | Descriptor: | CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS | Authors: | Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J. | Deposit date: | 2002-02-06 | Release date: | 2002-03-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21, 2002
|
|
6V5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v5v by Molmil](/molmil-images/mine/6v5v) | Structure of gamma-tubulin in the native human gamma-tubulin ring complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Tubulin gamma-1 chain | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
|
|
4OVU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ovu by Molmil](/molmil-images/mine/4ovu) | Crystal Structure of p110alpha in complex with niSH2 of p85alpha | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. | Deposit date: | 2014-01-14 | Release date: | 2014-09-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Structural basis of nSH2 regulation and lipid binding in PI3K alpha. Oncotarget, 5, 2014
|
|
4OVV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ovv by Molmil](/molmil-images/mine/4ovv) | Crystal Structure of PI3Kalpha in complex with diC4-PIP2 | Descriptor: | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, PHOSPHATE ION, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | Authors: | Gabelli, S.B, Vogelstein, B, Miller, M, Amzel, L.M. | Deposit date: | 2014-01-14 | Release date: | 2014-09-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis of nSH2 regulation and lipid binding in PI3K alpha. Oncotarget, 5, 2014
|
|
6V6B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v6b by Molmil](/molmil-images/mine/6v6b) | Structures of GCP2 and GCP3 in the native human gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 2, Gamma-tubulin complex component 3 | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
|
|
1KZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kz7 by Molmil](/molmil-images/mine/1kz7) | Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42 | Descriptor: | CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS | Authors: | Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J. | Deposit date: | 2002-02-06 | Release date: | 2002-03-20 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21, 2002
|
|
5ZHX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zhx by Molmil](/molmil-images/mine/5zhx) | |
5XGI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xgi by Molmil](/molmil-images/mine/5xgi) | Crystal structure of PI3K complex with an inhibitor | Descriptor: | 3-azanyl-5-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, GLYCEROL, HEXAETHYLENE GLYCOL, ... | Authors: | Song, K, Yang, X, Zhao, Y, Jian, Z. | Deposit date: | 2017-04-13 | Release date: | 2018-04-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Crystal structure of PI3K complex with an inhibitor To Be Published
|
|
7RM8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rm8 by Molmil](/molmil-images/mine/7rm8) | |
1MMD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mmd by Molmil](/molmil-images/mine/1mmd) | TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-BEF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Fisher, A.J, Holden, H.M, Rayment, I. | Deposit date: | 1995-03-21 | Release date: | 1996-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-. Biochemistry, 34, 1995
|
|
7S4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7s4e by Molmil](/molmil-images/mine/7s4e) | |
4P7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p7i by Molmil](/molmil-images/mine/4p7i) | Crystal structure of the Merlin FERM/DCAF1 complex | Descriptor: | GLYCEROL, Merlin, Protein VPRBP | Authors: | Wei, Z, Li, Y, Zhang, M. | Deposit date: | 2014-03-27 | Release date: | 2014-04-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1. J.Biol.Chem., 289, 2014
|
|
1MYO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1myo by Molmil](/molmil-images/mine/1myo) | SOLUTION STRUCTURE OF MYOTROPHIN, NMR, 44 STRUCTURES | Descriptor: | MYOTROPHIN | Authors: | Yang, Y, Nanduri, S, Sen, S, Qin, J. | Deposit date: | 1998-08-17 | Release date: | 1999-08-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin. Structure, 6, 1998
|
|
7TAB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tab by Molmil](/molmil-images/mine/7tab) | G-925 bound to the SMARCA4 (BRG1) Bromodomain | Descriptor: | 2-(6-amino-5-phenylpyridazin-3-yl)phenol, Isoform 4 of Transcription activator BRG1 | Authors: | Tang, Y, Poy, F, Taylor, A.M, Cochran, A.G, Bellon, S.F. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1. J.Med.Chem., 65, 2022
|
|
7TD9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7td9 by Molmil](/molmil-images/mine/7td9) | G-059 bound to the SMARCA4 (BRG1) Bromodomain | Descriptor: | 4-phenyl-5H-pyridazino[4,3-b]indol-3-amine, Isoform 4 of Transcription activator BRG1 | Authors: | Tang, Y, Poy, F, Taylor, A.M, Cochran, A.G, Bellon, S.F. | Deposit date: | 2021-12-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1. J.Med.Chem., 65, 2022
|
|
1LVK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lvk by Molmil](/molmil-images/mine/1lvk) | X-RAY CRYSTAL STRUCTURE OF THE MG (DOT) 2'(3')-O-(N-METHYLANTHRANILOYL) NUCLEOTIDE BOUND TO DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN | Descriptor: | 2'(3')-O-N-METHYLANTHRANILOYL-ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Bauer, C.B, Kuhlman, P.A, Bagshaw, C.R, Rayment, I. | Deposit date: | 1997-09-05 | Release date: | 1998-01-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray crystal structure and solution fluorescence characterization of Mg.2'(3')-O-(N-methylanthraniloyl) nucleotides bound to the Dictyostelium discoideum myosin motor domain. J.Mol.Biol., 274, 1997
|
|
6H1F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h1f by Molmil](/molmil-images/mine/6h1f) | Structure of the nanobody-stabilized gelsolin D187N variant (second domain) | Descriptor: | Gelsolin, THIOCYANATE ION, gelsolin nanobody, ... | Authors: | Hassan, A, Milani, M, Mastrangelo, E, de Rosa, M. | Deposit date: | 2018-07-11 | Release date: | 2019-01-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant. Biochim Biophys Acta Mol Basis Dis, 1865, 2019
|
|
7TM3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tm3 by Molmil](/molmil-images/mine/7tm3) | Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-01-19 | Release date: | 2022-10-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
|
|
7TUT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tut by Molmil](/molmil-images/mine/7tut) | Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-02-03 | Release date: | 2022-10-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
|
|
1MND
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mnd by Molmil](/molmil-images/mine/1mnd) | |