Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7PP1
DownloadVisualize
BU of 7pp1 by Molmil
Crystal structure of the P2Y12 receptor in complex with the inverse agonist selatogrel.
Descriptor: CHOLESTEROL, P2Y purinoceptor 12,Soluble cytochrome b562,P2Y purinoceptor 12, Selatogrel
Authors:Mac Sweeney, A, Tidten-Luksch, N.
Deposit date:2021-09-13
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Inverse agonist efficacy of selatogrel blunts constitutive P2Y12 receptor signaling by inducing the inactive receptor conformation.
Biochem Pharmacol, 206, 2022
7PZO
DownloadVisualize
BU of 7pzo by Molmil
mite allergen Der p 3 from Dermatophagoides pteronyssinus
Descriptor: SULFATE ION, mite allergen Der p 3
Authors:Timofeev, V.I, Shevtsov, M.B, Abramchik, Y.A, Mikheeva, O.O, Kostromina, M.A, Lykoshin, D.D, Zayats, E.A, Zavriev, S.K, Esipov, R.S, Kuranova, I.P.
Deposit date:2021-10-13
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural plasticity and thermal stability of the histone-like protein from Spiroplasma melliferum are due to phenylalanine insertions into the conservative scaffold.
J.Biomol.Struct.Dyn., 36, 2018
1PC9
DownloadVisualize
BU of 1pc9 by Molmil
Crystal Structure of BnSP-6, a Lys49-Phospholipase A2
Descriptor: BnSP-6
Authors:Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.M.
Deposit date:2003-05-16
Release date:2004-06-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.
Biochem.Biophys.Res.Commun., 311, 2003
7Q7K
DownloadVisualize
BU of 7q7k by Molmil
JAK2 in complex with 4-(2-amino-8-methoxyquinazolin-6-yl)phenol
Descriptor: 4-(2-azanyl-8-methoxy-quinazolin-6-yl)phenol, Tyrosine-protein kinase JAK2
Authors:Rowland, P.
Deposit date:2021-11-09
Release date:2022-02-02
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
J.Med.Chem., 65, 2022
7Q7L
DownloadVisualize
BU of 7q7l by Molmil
JAK2 in complex with 4-(2-amino-8-{[(2S)-1-hydroxypropan-2-yl]amino}quinazolin-6-yl)-5-ethyl-2-fluorophenol
Descriptor: 4-[2-azanyl-8-[[(2~{S})-1-oxidanylpropan-2-yl]amino]quinazolin-6-yl]-5-ethyl-2-fluoranyl-phenol, GLYCEROL, Tyrosine-protein kinase JAK2
Authors:Rowland, P.
Deposit date:2021-11-09
Release date:2022-02-02
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
J.Med.Chem., 65, 2022
7Q7I
DownloadVisualize
BU of 7q7i by Molmil
JAK2 in complex with 4-{8-methoxy-2-[(1-methyl-1H-pyrazol-4-yl)amino]quinazolin-6-yl}phenol
Descriptor: 4-[8-methoxy-2-[(1-methylpyrazol-4-yl)amino]quinazolin-6-yl]phenol, Tyrosine-protein kinase JAK2
Authors:Rowland, P.
Deposit date:2021-11-09
Release date:2022-02-02
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
J.Med.Chem., 65, 2022
7Q7W
DownloadVisualize
BU of 7q7w by Molmil
JAK2 in complex with 4-(2-{[5-(dimethylamino)pentyl]amino}-8-{[(2S)-1-hydroxypropan-2-yl]amino}quinazolin-6-yl)-5-ethyl-2-fluorophenol
Descriptor: 4-[2-[5-(dimethylamino)pentylamino]-8-[[(2~{S})-1-oxidanylpropan-2-yl]amino]quinazolin-6-yl]-5-ethyl-2-fluoranyl-phenol, Tyrosine-protein kinase JAK2
Authors:Rowland, P.
Deposit date:2021-11-09
Release date:2022-02-02
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
J.Med.Chem., 65, 2022
5EPD
DownloadVisualize
BU of 5epd by Molmil
Crystal structure of Glycerol Trinitrate Reductase XdpB from Agrobacterium sp. R89-1 (Apo form)
Descriptor: Glycerol trinitrate reductase
Authors:Kolenko, P, Zahradnik, J, Zuskova, I, Cerny, J, Palyzova, A, Kyslikova, E, Schneider, B.
Deposit date:2015-11-11
Release date:2016-11-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of XdpB, the bacterial old yellow enzyme, in an FMN-free form.
PLoS ONE, 13, 2018
5WOV
DownloadVisualize
BU of 5wov by Molmil
Solution NMR structure of cyclotide MCoTI-I
Descriptor: Two inhibitor peptide topologies 2
Authors:Schroeder, C.I, Kwon, S.
Deposit date:2017-08-03
Release date:2018-08-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Targeted Delivery of Cyclotides via Conjugation to a Nanobody.
ACS Chem. Biol., 13, 2018
8IFM
DownloadVisualize
BU of 8ifm by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 2
Descriptor: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
Authors:Zhang, J.T, Jia, N.
Deposit date:2023-02-18
Release date:2024-01-17
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
5WOW
DownloadVisualize
BU of 5wow by Molmil
Solution NMR structure of cyclotide MCoTI-I
Descriptor: Two inhibitor peptide topologies 2
Authors:Schroeder, C.I, Kwon, S.
Deposit date:2017-08-03
Release date:2018-08-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Targeted Delivery of Cyclotides via Conjugation to a Nanobody.
ACS Chem. Biol., 13, 2018
8IFL
DownloadVisualize
BU of 8ifl by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1
Descriptor: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
Authors:Zhang, J.T, Jia, N.
Deposit date:2023-02-18
Release date:2024-01-17
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
8IFK
DownloadVisualize
BU of 8ifk by Molmil
Cryo-EM structure of monomeric SPARTA gRNA-ssDNA target complex
Descriptor: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
Authors:Zhang, J.T, Jia, N.
Deposit date:2023-02-18
Release date:2024-01-17
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
7KTS
DownloadVisualize
BU of 7kts by Molmil
Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
Descriptor: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ...
Authors:Herbst, D.A, Esbin, M.N, Nogales, E.
Deposit date:2020-11-24
Release date:2021-11-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (19.09 Å)
Cite:Structure of the human SAGA coactivator complex.
Nat.Struct.Mol.Biol., 28, 2021
1L63
DownloadVisualize
BU of 1l63 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Nicholson, H, Matthews, B.W.
Deposit date:1991-05-06
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme.
Biochemistry, 30, 1991
5MR2
DownloadVisualize
BU of 5mr2 by Molmil
Crystal structure of red abalone VERL repeat 2 with linker at 2.5 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Vitelline envelope sperm lysin receptor
Authors:Sadat Al-Hosseini, H, Raj, I, Nishimura, K, De Sanctis, D, Jovine, L.
Deposit date:2016-12-21
Release date:2017-06-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Cell, 169, 2017
5M7N
DownloadVisualize
BU of 5m7n by Molmil
Crystal structure of NtrX from Brucella abortus in complex with ATP processed with the CrystalDirect automated mounting and cryo-cooling technology
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nitrogen assimilation regulatory protein
Authors:Cornaciu, I, Fernandez, I, Hoffmann, G, Carrica, M.C, Goldbaum, F.A, Marquez, J.A.
Deposit date:2016-10-28
Release date:2017-01-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Three-Dimensional Structure of Full-Length NtrX, an Unusual Member of the NtrC Family of Response Regulators.
J. Mol. Biol., 429, 2017
7LF8
DownloadVisualize
BU of 7lf8 by Molmil
Fab 6D12 bound to ApoL2 NTD
Descriptor: Apolipoprotein L2, Fab 6D12 heavy chain, Fab 6D12 light chain, ...
Authors:Ultsch, M, Kirchhofer, D.
Deposit date:2021-01-15
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
7RNT
DownloadVisualize
BU of 7rnt by Molmil
CRYSTAL STRUCTURE OF THE TYR45TRP MUTANT OF RIBONUCLEASE T1 IN A COMPLEX WITH 2'-ADENYLIC ACID
Descriptor: ADENOSINE-2'-MONOPHOSPHATE, CALCIUM ION, RIBONUCLEASE T1
Authors:Koellner, G, Grunert, H.-P, Landt, O, Saenger, W.
Deposit date:1991-08-20
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2'-adenylic acid.
Eur.J.Biochem., 201, 1991
1L55
DownloadVisualize
BU of 1l55 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Nicholson, H, Matthews, B.W.
Deposit date:1991-05-06
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme.
Biochemistry, 30, 1991
7R0S
DownloadVisualize
BU of 7r0s by Molmil
Structure of a cytosolic sulfotransferase of Anopheles gambiae (AGAP001425) in complex with vanillin
Descriptor: 4-hydroxy-3-methoxybenzaldehyde, AGAP001425-PA, CHLORIDE ION, ...
Authors:Esposito Verza, A, Miggiano, R, Rizzi, R, Rossi, F.
Deposit date:2022-02-02
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues.
Curr Res Struct Biol, 4, 2022
5N83
DownloadVisualize
BU of 5n83 by Molmil
Structure of the distal domain of mouse adenovirus 2 fibre, methylmercury chloride derivative
Descriptor: Fiber, MERCURY (II) ION
Authors:Singh, A.K, van Raaij, M.J.
Deposit date:2017-02-22
Release date:2018-03-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre.
J. Gen. Virol., 99, 2018
5YW2
DownloadVisualize
BU of 5yw2 by Molmil
Crystal structure of Adenine phosphoribosyltransferase from Francisella tularensis.
Descriptor: Adenine phosphoribosyltransferase, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Pavithra, G.C, Ramagopal, U.A.
Deposit date:2017-11-28
Release date:2018-01-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structures of APRT from Francisella tularensis - an N-H···N hydrogen bond imparts adenine specificity in adenine phosporibosyltransferases.
FEBS J., 285, 2018
7SCY
DownloadVisualize
BU of 7scy by Molmil
Nuc147 bound to single BRCT
Descriptor: DNA (147-MER), Histone H2A, Histone H2B type 1-J, ...
Authors:Muthurajan, U.M, Rudolph, J.R.
Deposit date:2021-09-29
Release date:2022-01-12
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
Mol.Cell, 81, 2021
7SCZ
DownloadVisualize
BU of 7scz by Molmil
Nuc147 bound to multiple BRCTs
Descriptor: DNA (147-MER), Histone H2A, Histone H2B type 1-J, ...
Authors:Muthurajan, U.M, Rudolph, J.
Deposit date:2021-09-29
Release date:2022-01-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
Mol.Cell, 81, 2021

225399

數據於2024-09-25公開中

PDB statisticsPDBj update infoContact PDBjnumon