2FV8
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![BU of 2fv8 by Molmil](/molmil-images/mine/2fv8) | The crystal structure of RhoB in the GDP-bound state | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Rho-related GTP-binding protein RhoB | Authors: | Turnbull, A.P, Soundararajan, M, Smee, C, Johansson, C, Schoch, G, Gorrec, F, Bray, J, Papagrigoriou, E, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2006-01-30 | Release date: | 2006-02-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of RhoB in the GDP-bound state To be Published
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4TW3
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![BU of 4tw3 by Molmil](/molmil-images/mine/4tw3) | Insights into Substrate and Metal Binding from the Crystal Structure of Cyanobacterial Aldehyde Deformylating Oxygenase with Substrate Bound | Descriptor: | 1,2-ETHANEDIOL, Aldehyde decarbonylase, FE (III) ION, ... | Authors: | Buer, B.C, Paul, B, Das, D, Stuckey, J.A, Marsh, E.N.G. | Deposit date: | 2014-06-29 | Release date: | 2014-10-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into substrate and metal binding from the crystal structure of cyanobacterial aldehyde deformylating oxygenase with substrate bound. Acs Chem.Biol., 9, 2014
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2FW3
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![BU of 2fw3 by Molmil](/molmil-images/mine/2fw3) | Crystal structure of rat carnitine palmitoyltransferase 2 in complex with antidiabetic drug ST1326 | Descriptor: | (3R)-3-{[(TETRADECYLAMINO)CARBONYL]AMINO}-4-(TRIMETHYLAMMONIO)BUTANOATE, Carnitine O-palmitoyltransferase II, mitochondrial | Authors: | Rufer, A.C, Thoma, R, Benz, J, Stihle, M, Gsell, B, De Roo, E, Banner, D.W, Mueller, F, Chomienne, O, Hennig, M. | Deposit date: | 2006-02-01 | Release date: | 2007-02-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment Structure, 14, 2006
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4TWC
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![BU of 4twc by Molmil](/molmil-images/mine/4twc) | 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e | Descriptor: | 2-{[2-(trifluoromethoxy)benzoyl]amino}-N-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1,3-thiazole-4-carboxamide, Casein kinase I isoform delta, DIMETHYL SULFOXIDE, ... | Authors: | Bischof, J, Leban, L, Zaja, M, Grothey, A, Radunsky, B, Othersen, O, Strobl, S, Vitt, D, Knippschild, U. | Deposit date: | 2014-06-30 | Release date: | 2014-10-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1d/e. Amino Acids, 43, 2012
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4TWI
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![BU of 4twi by Molmil](/molmil-images/mine/4twi) | The structure of Sir2Af1 bound to a succinylated histone peptide | Descriptor: | GLYCEROL, NAD-dependent protein deacylase 1, Succinylated H4 Peptide (aa8-20), ... | Authors: | Ringel, A.E, Roman, C, Wolberger, C. | Deposit date: | 2014-06-30 | Release date: | 2014-12-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2. Protein Sci., 23, 2014
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4TWU
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2FW7
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![BU of 2fw7 by Molmil](/molmil-images/mine/2fw7) | |
2FR9
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![BU of 2fr9 by Molmil](/molmil-images/mine/2fr9) | NMR structure of the alpha-conotoxin GI (SER12)-benzoylphenylalanine derivative | Descriptor: | Alpha-conotoxin GI | Authors: | Pashkov, V.S, Maslennikov, I.V, Kasheverov, I.E, Zhmak, M.N, Utkin, Y.N, Tsetlin, V.I, Arseniev, A.S. | Deposit date: | 2006-01-19 | Release date: | 2006-05-30 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Alpha-Conotoxin GI benzoylphenylalanine derivatives. (1)H-NMR structures and photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor. Febs J., 273, 2006
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8EDI
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![BU of 8edi by Molmil](/molmil-images/mine/8edi) | Structure of C. elegans UNC-5 IG 1+2 Domains bound to Heparin dp4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Netrin receptor unc-5 | Authors: | Priest, J.M, Ozkan, E. | Deposit date: | 2022-09-04 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structure of C. elegans UNC-5 IG 1+2 Domains To Be Published
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2FW8
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2FZU
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![BU of 2fzu by Molmil](/molmil-images/mine/2fzu) | Reduced enolate chromophore intermediate for GFP variant | Descriptor: | 1,2-ETHANEDIOL, Green fluorescent protein, MAGNESIUM ION | Authors: | Barondeau, D.P, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2006-02-10 | Release date: | 2006-03-14 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural evidence for an enolate intermediate in GFP fluorophore biosynthesis. J.Am.Chem.Soc., 128, 2006
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4U2S
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7XSV
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![BU of 7xsv by Molmil](/molmil-images/mine/7xsv) | Crystal Structures of PIM1 in Complex with Macrocyclic Compound H3 | Descriptor: | 8-Methyl-2,5,20-trioxa-8,13,17-triazatetracyclo[11.10.2.014,19.021,25]pentacosa-1(24),14(19),15,17,21(25),22-hexaene, Serine/threonine-protein kinase pim-1 | Authors: | Shen, C, Xie, Y, Ren, X, Zhou, Y, Niu, H. | Deposit date: | 2022-05-15 | Release date: | 2022-07-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3-e][1,4]oxazine derivatives as novel Pim-1 kinase inhibitors. Bioorg.Med.Chem.Lett., 72, 2022
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2G9J
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![BU of 2g9j by Molmil](/molmil-images/mine/2g9j) | Complex of TM1a(1-14)Zip with TM9a(251-284): a model for the polymerization domain ("overlap region") of tropomyosin, Northeast Structural Genomics Target OR9 | Descriptor: | Tropomyosin 1 alpha chain, Tropomyosin 1 alpha chain/General control protein GCN4 | Authors: | Greenfield, N.J, Huang, Y.J, Swapna, G.V.T, Bhattacharya, A, Singh, A, Montelione, G.T, Hitchcock-DeGregori, S.E, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-03-06 | Release date: | 2006-11-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the Junction between Tropomyosin Molecules: Implications for Actin Binding and Regulation. J.Mol.Biol., 364, 2006
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4UCK
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![BU of 4uck by Molmil](/molmil-images/mine/4uck) | X-ray structure and activities of an essential Mononegavirales L- protein domain | Descriptor: | RNA-DIRECTED RNA POLYMERASE L, S-ADENOSYLMETHIONINE, ZINC ION | Authors: | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | Deposit date: | 2014-12-03 | Release date: | 2015-11-18 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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4UCZ
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![BU of 4ucz by Molmil](/molmil-images/mine/4ucz) | X-ray structure and activities of an essential Mononegavirales L- protein domain | Descriptor: | GUANOSINE, GUANOSINE-5'-TRIPHOSPHATE, RNA-DIRECTED RNA POLYMERASE L, ... | Authors: | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | Deposit date: | 2014-12-05 | Release date: | 2015-11-18 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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4TW1
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![BU of 4tw1 by Molmil](/molmil-images/mine/4tw1) | Crystal structure of the octameric pore complex of the Staphylococcus aureus Bi-component Toxin LukGH | Descriptor: | Possible leukocidin subunit | Authors: | Logan, D.T, Hakansson, M, Saline, M, Kimbung, R, Badarau, A, Rouha, H, Nagy, E. | Deposit date: | 2014-06-29 | Release date: | 2014-11-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH. J.Biol.Chem., 290, 2015
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8DRQ
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![BU of 8drq by Molmil](/molmil-images/mine/8drq) | LRRC8A:C conformation 1 (round) LRR focus 3 | Descriptor: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | Authors: | Kern, D.M, Brohawn, S.G. | Deposit date: | 2022-07-21 | Release date: | 2023-03-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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2FYR
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2G1E
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![BU of 2g1e by Molmil](/molmil-images/mine/2g1e) | Solution Structure of TA0895 | Descriptor: | hypothetical protein Ta0895 | Authors: | Yeo, I.Y, Hong, E, Jung, J, Lee, W, Yee, A, Arrowsmith, C.H. | Deposit date: | 2006-02-14 | Release date: | 2006-12-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of TA0895, a MoaD homologue from Thermoplasma acidophilum Proteins, 65, 2006
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2G5G
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2GHY
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![BU of 2ghy by Molmil](/molmil-images/mine/2ghy) | Novel Crystal Form of the ColE1 Rom Protein | Descriptor: | Regulatory protein rop | Authors: | Jang, S.B, Jeong, M.S, Carter, R.J, Holbrook, E.L, Comolli, L.R, Holbrook, S.R. | Deposit date: | 2006-03-28 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Novel crystal form of the ColE1 Rom protein. Acta Crystallogr.,Sect.D, 62, 2006
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2FWA
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4U6S
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![BU of 4u6s by Molmil](/molmil-images/mine/4u6s) | CtBP1 in complex with substrate phenylpyruvate | Descriptor: | 3-PHENYLPYRUVIC ACID, C-terminal-binding protein 1, CALCIUM ION, ... | Authors: | Hilbert, B.J, Morris, B.L, Ellis, K.C, Paulsen, J.L, Schiffer, C.A, Grossman, S.R, Royer Jr, W.E. | Deposit date: | 2014-07-29 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Guided Design of a High Affinity Inhibitor to Human CtBP. Acs Chem.Biol., 10, 2015
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2G3Y
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![BU of 2g3y by Molmil](/molmil-images/mine/2g3y) | Crystal structure of the human small GTPase GEM | Descriptor: | GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE | Authors: | Ugochukwu, E, Soundararajan, M, Elkins, J, Gileadi, C, Schoch, G, Sobott, F, Fedorov, O, Bray, J, Pantic, N, Berridge, G, Burgess, N, Lee, W.H, Turnbull, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2006-02-21 | Release date: | 2006-04-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the human small GTPase GEM To be Published
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