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8AEL
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BU of 8ael by Molmil
SYNJ2BP complex with a synthetic Vangl2 peptide (3mer).
Descriptor: CALCIUM ION, GLY-GLY-GLY-THR-SER-VAL, GLYCEROL, ...
Authors:Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G.
Deposit date:2022-07-13
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide.
To Be Published
3EGG
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BU of 3egg by Molmil
Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Spinophilin
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MANGANESE (II) ION, ...
Authors:Ragusa, M.J, Page, R, Peti, W.
Deposit date:2008-09-10
Release date:2010-03-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
3GCO
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BU of 3gco by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYQF OMP peptide
Descriptor: DNRDGNVYQF peptide, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-22
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GDS
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BU of 3gds by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYYF peptide
Descriptor: DNRDGNVYYF peptide, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GDU
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BU of 3gdu by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YRF peptide
Descriptor: DegS protease, YRF peptide
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GCN
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BU of 3gcn by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with OMP peptide (YQF)
Descriptor: Protease degS, YQF peptide
Authors:Sohn, J, Sauer, R.T, Grant, R.A.
Deposit date:2009-02-22
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Mechanisms of allosteric activation of the DegS protease by OMP-peptide binding and protein-substrate binding
To be Published
3GDV
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BU of 3gdv by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YQF peptide
Descriptor: DegS protease, YQF peptide
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.489 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3EGH
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BU of 3egh by Molmil
Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1), the PP1 binding and PDZ domains of Spinophilin and the small natural molecular toxin Nodularin-R
Descriptor: GLYCEROL, MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ...
Authors:Ragusa, M.J, Page, R, Peti, W.
Deposit date:2008-09-10
Release date:2010-03-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
2R3Y
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BU of 2r3y by Molmil
Crystal structure of the DegS protease in complex with the YWF activating peptide
Descriptor: Protease degS, Synthetic peptide YWF
Authors:Clausen, T, Hasselblatt, H.
Deposit date:2007-08-30
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
4RQZ
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BU of 4rqz by Molmil
re-refinement of 1soz, Crystal Structure of DegS protease in complex with an activating peptide
Descriptor: Protease degS, activating peptide
Authors:Sauer, R.T, Grant, R.A.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
4RR0
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BU of 4rr0 by Molmil
re-refined 1vcw, CRYSTAL STRUCTURE OF DEGS AFTER BACKSOAKING THE ACTIVATING PEPTIDE
Descriptor: Protease degS
Authors:Sauer, R.T, Grant, R.A.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.054 Å)
Cite:A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
2XKX
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BU of 2xkx by Molmil
Single particle analysis of PSD-95 in negative stain
Descriptor: DISKS LARGE HOMOLOG 4
Authors:Fomina, S, Howard, T.D, Sleator, O.K, Golovanova, M, O'Ryan, L, Leyland, M.L, Grossmann, J.G, Collins, R.F, Prince, S.M.
Deposit date:2010-07-15
Release date:2011-07-20
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (22.9 Å), SOLUTION SCATTERING
Cite:Self-Directed Assembly and Clustering of the Cytoplasmic Domains of Inwardly Rectifying Kir2.1 Potassium Channels on Association with Psd-95
Biochim.Biophys.Acta, 1808, 2011
4RQY
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BU of 4rqy by Molmil
RE-REFINED STRUCTURE OF 1TE0 - STRUCTURAL ANALYSIS of DEGS, A STRESS SENSOR OF THE BACTERIAL PERIPLASM
Descriptor: PHOSPHATE ION, Protease degS
Authors:Sauer, R.T, Grant, R.A.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
4RR1
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BU of 4rr1 by Molmil
re-refinement of entry 1sot, Crystal Structure of the DegS stress sensor
Descriptor: NICKEL (II) ION, PHOSPHATE ION, Protease degS
Authors:Sauer, R.T, Grant, R.A.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
8BW9
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BU of 8bw9 by Molmil
Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP
Descriptor: Connector enhancer of KSR protein CNK, Dual specificity mitogen-activated protein kinase kinase dSOR1, KSR, ...
Authors:Maisonneuve, P, Fronzes, R, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 2024
8BW8
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BU of 8bw8 by Molmil
Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex
Descriptor: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle
Authors:Maisonneuve, P, Kurinov, I, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 2024
7PC4
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BU of 7pc4 by Molmil
The PDZ domain of SNTB1 complexed with the PDZ-binding motif of HTLV1-TAX1
Descriptor: 1,2-ETHANEDIOL, Beta-1-syntrophin,Annexin A2, CALCIUM ION, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC5
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BU of 7pc5 by Molmil
The third PDZ domain of PDZD7 complexed with the PDZ-binding motif of EXOC4
Descriptor: CALCIUM ION, Exocyst complex component 4, GLYCEROL, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PCB
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BU of 7pcb by Molmil
The PDZ domain of SNX27 fused with ANXA2
Descriptor: CALCIUM ION, GLYCEROL, Sorting nexin-27,Annexin A2
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC8
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BU of 7pc8 by Molmil
The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ-binding motif of RSK1
Descriptor: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC7
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BU of 7pc7 by Molmil
The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of PTEN
Descriptor: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC9
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BU of 7pc9 by Molmil
The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1
Descriptor: CALCIUM ION, Protein Tax-1, Synaptojanin-2-binding protein,Annexin A2
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC3
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BU of 7pc3 by Molmil
The second PDZ domain of DLG1 complexed with the PDZ-binding motif of HTLV1-TAX1
Descriptor: CALCIUM ION, Disks large homolog 1,Annexin A2, GLYCEROL, ...
Authors:Cousido-Siah, A, Trave, G, Gogl, G.
Deposit date:2021-08-03
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7P73
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BU of 7p73 by Molmil
The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1
Descriptor: CALCIUM ION, GLYCEROL, Protein Tax-1, ...
Authors:Gogl, G, Cousido-Siah, A, Trave, G.
Deposit date:2021-07-19
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Quantitative fragmentomics allow affinity mapping of interactomes.
Nat Commun, 13, 2022
7P74
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BU of 7p74 by Molmil
The PDZ domain of SYNJ2BP complexed with the phosphorylated PDZ-binding motif of RSK1
Descriptor: CALCIUM ION, GLYCEROL, Ribosomal protein S6 kinase alpha-1, ...
Authors:Gogl, G, Cousido-Siah, A, Trave, G.
Deposit date:2021-07-19
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Quantitative fragmentomics allow affinity mapping of interactomes.
Nat Commun, 13, 2022

222415

數據於2024-07-10公開中

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