7AXZ
| Ku70/80 complex apo form | Descriptor: | X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6 | Authors: | Hnizda, A, Tesina, P, Novak, P, Blundell, T.L. | Deposit date: | 2020-11-10 | Release date: | 2021-02-10 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | SAP domain forms a flexible part of DNA aperture in Ku70/80. Febs J., 288, 2021
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3BWE
| Crystal structure of aggregated form of DJ1 | Descriptor: | PHOSPHATE ION, Protein DJ-1 | Authors: | Cha, S.S. | Deposit date: | 2008-01-09 | Release date: | 2008-10-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of filamentous aggregates of human DJ-1 formed in an inorganic phosphate-dependent manner. J.Biol.Chem., 283, 2008
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3S7B
| Structural Basis of Substrate Methylation and Inhibition of SMYD2 | Descriptor: | (R,R)-2,3-BUTANEDIOL, N-cyclohexyl-N~3~-[2-(3,4-dichlorophenyl)ethyl]-N-(2-{[2-(5-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]amino}ethyl)-beta-alaninamide, N-lysine methyltransferase SMYD2, ... | Authors: | Ferguson, A.D. | Deposit date: | 2011-05-26 | Release date: | 2011-08-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structural Basis of Substrate Methylation and Inhibition of SMYD2. Structure, 19, 2011
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3CZ9
| Crystal Structure of E18L DJ-1 | Descriptor: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Protein DJ-1 | Authors: | Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A. | Deposit date: | 2008-04-28 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47, 2008
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3UVL
| Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL3 | Descriptor: | Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5 | Authors: | Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. | Deposit date: | 2011-11-30 | Release date: | 2011-12-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
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7UAK
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3CYF
| Crystal Structure of E18N DJ-1 | Descriptor: | Protein DJ-1 | Authors: | Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A. | Deposit date: | 2008-04-25 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47, 2008
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3CZA
| Crystal Structure of E18D DJ-1 | Descriptor: | MALONIC ACID, Protein DJ-1 | Authors: | Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hashim, S, Pozharski, E, Wilson, M.A. | Deposit date: | 2008-04-28 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47, 2008
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3UVK
| Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL2 | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase MLL2, SULFATE ION, ... | Authors: | Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. | Deposit date: | 2011-11-30 | Release date: | 2011-12-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
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3CY6
| Crystal Structure of E18Q DJ-1 | Descriptor: | Protein DJ-1 | Authors: | Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A. | Deposit date: | 2008-04-25 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47, 2008
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2PUU
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3S7F
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3B3A
| Structure of E163K/R145E DJ-1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Protein DJ-1 | Authors: | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | Deposit date: | 2007-10-19 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
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7AXU
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3S7J
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7N7I
| X-ray crystal structure of Viperin-like enzyme from Trichoderma virens | Descriptor: | IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, URIDINE 5'-TRIPHOSPHATE, ... | Authors: | Grove, T.L, Almo, S.C, Bonanno, J.B, Lachowicz, J.C, Gizzi, A.G. | Deposit date: | 2021-06-10 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structural Insight into the Substrate Scope of Viperin and Viperin-like Enzymes from Three Domains of Life. Biochemistry, 60, 2021
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7AXQ
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7AXP
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7AXX
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7AXS
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7N7H
| X-ray crystal structure of Viperin-like enzyme from Nematostella vectensis | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... | Authors: | Grove, T.L, Almo, S.C, Bonanno, J.B, Lachowicz, J.C, Gizzi, A.G. | Deposit date: | 2021-06-10 | Release date: | 2021-07-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural Insight into the Substrate Scope of Viperin and Viperin-like Enzymes from Three Domains of Life. Biochemistry, 60, 2021
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7QHS
| S. cerevisiae CMGE nucleating origin DNA melting | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... | Authors: | Lewis, J.S, Sousa, J.S, Costa, A. | Deposit date: | 2021-12-14 | Release date: | 2022-06-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanism of replication origin melting nucleated by CMG helicase assembly. Nature, 606, 2022
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7AG0
| Complex between the bone morphogenetic protein 2 and its antagonist Noggin | Descriptor: | Bone morphogenetic protein 2, GLYCEROL, Noggin | Authors: | Robert, C, Bruck, F, Herman, R, Vandevenne, M, Filee, P, Kerff, F, Matagne, A. | Deposit date: | 2020-09-21 | Release date: | 2022-04-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.104 Å) | Cite: | Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition. J.Biol.Chem., 299, 2023
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7AYY
| Structure of the human 8-oxoguanine DNA Glycosylase hOGG1 in complex with activator TH10785 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, N-glycosylase/DNA lyase, ... | Authors: | Masuyer, G, Davies, J.R, Stenmark, P. | Deposit date: | 2020-11-13 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
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1ODH
| Structure of the GCM domain bound to DNA | Descriptor: | 5'-D(*CP*GP*AP*TP*GP*CP*GP*GP*GP*TP *GP*CP*A)-3', 5'-D(*TP*GP*CP*AP*CP*CP*CP*GP*CP*AP *TP*CP*G)-3', MGCM1, ... | Authors: | Cohen, S.X, Muller, C.W. | Deposit date: | 2003-02-19 | Release date: | 2003-04-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structure of the Gcm Domain-DNA Complex: A DNA-Binding Domain with a Novel Fold and Mode of Target Site Recognition Embo J., 22, 2003
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