2EMO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2emo by Molmil](/molmil-images/mine/2emo) | |
7K18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k18 by Molmil](/molmil-images/mine/7k18) | Cardiac Sodium channel with toxin bound | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-like toxin Lqh3, ... | Authors: | Jiang, D, Catterall, W.A. | Deposit date: | 2020-09-07 | Release date: | 2021-01-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin. Nat Commun, 12, 2021
|
|
8T6L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t6l by Molmil](/molmil-images/mine/8t6l) | Cryo-EM structure of rat cardiac sodium channel NaV1.5 with batrachotoxin analog BTX-B | Descriptor: | (1R)-1-[(5aR,7aR,9R,11aS,11bS,12R,13aR)-9,12-dihydroxy-2,11a-dimethyl-1,2,3,4,7a,8,9,10,11,11a,12,13-dodecahydro-7H-9,11b-epoxy-13a,5a-prop[1]enophenanthro[2,1-f][1,4]oxazepin-14-yl]ethyl benzoate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ... | Authors: | Tonggu, L, Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A. | Deposit date: | 2023-06-16 | Release date: | 2024-03-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin. Nat Commun, 15, 2024
|
|
8T18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t18 by Molmil](/molmil-images/mine/8t18) | |
8T15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t15 by Molmil](/molmil-images/mine/8t15) | |
8T17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t17 by Molmil](/molmil-images/mine/8t17) | |
8T6K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t6k by Molmil](/molmil-images/mine/8t6k) | |
8T6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t6q by Molmil](/molmil-images/mine/8t6q) | |
6UZ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uz3 by Molmil](/molmil-images/mine/6uz3) | Cardiac sodium channel | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jiang, D, Shi, H, Tonggu, L, Lenaeus, M.J, Zheng, N, Catterall, W.A. | Deposit date: | 2019-11-14 | Release date: | 2020-01-01 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Cardiac Sodium Channel. Cell, 180, 2020
|
|
7KS0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ks0 by Molmil](/molmil-images/mine/7ks0) | GluK2/K5 with 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX) | Descriptor: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | Authors: | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | Deposit date: | 2020-11-20 | Release date: | 2021-03-24 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife, 10, 2021
|
|
7KS3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ks3 by Molmil](/molmil-images/mine/7ks3) | GluK2/K5 with L-Glu | Descriptor: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | Authors: | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | Deposit date: | 2020-11-20 | Release date: | 2021-03-24 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife, 10, 2021
|
|
6UZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uz0 by Molmil](/molmil-images/mine/6uz0) | Cardiac sodium channel with flecainide | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jiang, D, Shi, H, Tonggu, L, Lenaeus, M.J, Zheng, N, Catterall, W.A. | Deposit date: | 2019-11-14 | Release date: | 2020-01-01 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structure of the Cardiac Sodium Channel. Cell, 180, 2020
|
|
7KUY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kuy by Molmil](/molmil-images/mine/7kuy) | |
6WVI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wvi by Molmil](/molmil-images/mine/6wvi) | VKOR-like from Takifugu rubripes | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Vitamin K epoxide reductase-like protein, termini restrained by green fluorescent protein | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-06 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
|
|
3V3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v3d by Molmil](/molmil-images/mine/3v3d) | |
2P4M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2p4m by Molmil](/molmil-images/mine/2p4m) | High pH structure of Rtms5 H146S variant | Descriptor: | GFP-like non-fluorescent chromoprotein, IODIDE ION | Authors: | Battad, J.M, Wilmann, P.G, Olsen, S, Byres, E, Smith, S.C, Dove, S.G, Turcic, K.N, Devenish, R.J, Rossjohn, J, Prescott, M. | Deposit date: | 2007-03-12 | Release date: | 2007-04-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A structural basis for the pH-dependent increase in fluorescence efficiency of chromoproteins J.Mol.Biol., 368, 2007
|
|
7SSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ssx by Molmil](/molmil-images/mine/7ssx) | Structure of human Kv1.3 | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion | Authors: | Meyerson, J.R, Selvakumar, P. | Deposit date: | 2021-11-11 | Release date: | 2022-06-29 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
|
|
7SSZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ssz by Molmil](/molmil-images/mine/7ssz) | Structure of human Kv1.3 with A0194009G09 nanobodies | Descriptor: | Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion | Authors: | Meyerson, J.R, Selvakumar, P. | Deposit date: | 2021-11-11 | Release date: | 2022-06-29 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
|
|
7SSY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ssy by Molmil](/molmil-images/mine/7ssy) | Structure of human Kv1.3 (alternate conformation) | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion | Authors: | Meyerson, J.R, Selvakumar, P. | Deposit date: | 2021-11-11 | Release date: | 2022-06-29 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
|
|
7SSV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ssv by Molmil](/molmil-images/mine/7ssv) | Structure of human Kv1.3 with Fab-ShK fusion | Descriptor: | Fab-ShK fusion, heavy chain, light chain, ... | Authors: | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | Deposit date: | 2021-11-11 | Release date: | 2022-06-29 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
|
|
8F6P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f6p by Molmil](/molmil-images/mine/8f6p) | Rat Cardiac Sodium Channel with Ranolazine Bound | Descriptor: | (R)-ranolazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lenaeus, M.J, Tonggu, L. | Deposit date: | 2022-11-16 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural Basis for Inhibition of the Cardiac Sodium Channel by the Atypical Antiarrhythmic Drug Ranolazine To Be Published
|
|
1KYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kyp by Molmil](/molmil-images/mine/1kyp) | Crystal Structure of an Apo Green Fluorescent Protein Zn Biosensor | Descriptor: | Green Fluorescent Protein, MAGNESIUM ION | Authors: | Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2002-02-05 | Release date: | 2002-04-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural chemistry of a green fluorescent protein Zn biosensor. J.Am.Chem.Soc., 124, 2002
|
|
1KYS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kys by Molmil](/molmil-images/mine/1kys) | Crystal Structure of a Zn-bound Green Fluorescent Protein Biosensor | Descriptor: | Green Fluorescent Protein, ZINC ION | Authors: | Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2002-02-05 | Release date: | 2002-04-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Structural chemistry of a green fluorescent protein Zn biosensor. J.Am.Chem.Soc., 124, 2002
|
|
1KYR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kyr by Molmil](/molmil-images/mine/1kyr) | Crystal Structure of a Cu-bound Green Fluorescent Protein Zn Biosensor | Descriptor: | COPPER (II) ION, Green Fluorescent Protein, MAGNESIUM ION | Authors: | Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2002-02-05 | Release date: | 2002-04-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural chemistry of a green fluorescent protein Zn biosensor. J.Am.Chem.Soc., 124, 2002
|
|
1MOU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mou by Molmil](/molmil-images/mine/1mou) | Crystal structure of Coral pigment | Descriptor: | GFP-like non-fluorescent chromoprotein, IODIDE ION | Authors: | Prescott, M, Ling, M, Beddoe, T, Oakley, A.J, Dove, S, Hoegh-Guldberg, O, Devenish, R.J, Rossjohn, J. | Deposit date: | 2002-09-10 | Release date: | 2003-04-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The 2.2 a crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation. Structure, 11, 2003
|
|