4GVM
 
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5C1G
 | | Crystal structure of ABBA + UDP + DI | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, GALACTOSE-URIDINE-5'-DIPHOSPHATE, Histo-blood group ABO system transferase, ... | | Authors: | Gagnon, S. | | Deposit date: | 2015-06-13 | | Release date: | 2015-09-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | High Resolution Structures of the Human ABO(H) Blood Group Enzymes in Complex with Donor Analogs Reveal That the Enzymes Utilize Multiple Donor Conformations to Bind Substrates in a Stepwise Manner.
J.Biol.Chem., 290, 2015
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5E4R
 | | Crystal structure of domain-duplicated synthetic class II ketol-acid reductoisomerase 2Ia_KARI-DD | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Ketol-acid reductoisomerase, ... | | Authors: | Cahn, J.K.B, Brinkmann-Chen, S, Buller, A.R, Arnold, F.H. | | Deposit date: | 2015-10-07 | | Release date: | 2015-12-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Artificial domain duplication replicates evolutionary history of ketol-acid reductoisomerases.
Protein Sci., 25, 2016
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4H9M
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4HFW
 | | Anti Rotavirus Antibody | | Descriptor: | 6-26 Fab Heavy chain, 6-26 Fab Light chain, SULFATE ION | | Authors: | Spiller, B.W, Aiyegbo, M, Crowe, J.E. | | Deposit date: | 2012-10-05 | | Release date: | 2013-05-29 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore.
Plos One, 8, 2013
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3IRX
 | | Crystal Structure of HIV-1 reverse transcriptase (RT) in complex with the Non-nucleoside RT Inhibitor (E)-S-Methyl 5-(1-(3,7-Dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methylbenzothioate. | | Descriptor: | (E)-S-Methyl 5-(1-(3,7-Dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methy lbenzothioate, Reverse transcriptase, Reverse transcriptase/ribonuclease H | | Authors: | Ho, W.C, Arnold, E. | | Deposit date: | 2009-08-24 | | Release date: | 2010-04-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of HIV-1 reverse transcriptase (RT) in complex with the
alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor (E)-S-Methyl
5-(1-(3,7-Dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methylbenzothioate.
J.Med.Chem., 52, 2009
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5DW8
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4K7S
 | | Crystal structure of Zn2-hUb (human ubiquitin) adduct from a solution 35 mM zinc acetate/1.3 mM hUb | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ZINC ION, ... | | Authors: | Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G. | | Deposit date: | 2013-04-17 | | Release date: | 2013-05-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Conformational selection of ubiquitin quaternary structures driven by zinc ions.
Chemistry, 19, 2013
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4DYU
 | | The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10 | | Descriptor: | DNA protection during starvation protein, SULFATE ION, ZINC ION | | Authors: | Tan, K, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2012-02-29 | | Release date: | 2012-03-14 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10
To be Published
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4E22
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5EBK
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4L78
 | | Xenon Trapping and Statistical Coupling Analysis Uncover Regions Important for Structure and Function of Multidomain Protein StPurL | | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Tanwar, A.S, Goyal, V.D, Choudhary, D, Panjikar, S, Anand, R. | | Deposit date: | 2013-06-13 | | Release date: | 2013-12-11 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis
Plos One, 8, 2013
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4IAG
 | | Crystal structure of ZbmA, the zorbamycin binding protein from Streptomyces flavoviridis | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Zbm binding protein | | Authors: | Cuff, M.E, Bigelow, L, Bruno, C.J.P, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | Deposit date: | 2012-12-06 | | Release date: | 2013-02-20 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892.
Biochemistry, 54, 2015
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4HU9
 | | E. coli thioredoxin variant with (4S)-FluoroPro76 as single proline residue | | Descriptor: | COPPER (II) ION, Thioredoxin-1 | | Authors: | Scharer, M.A, Rubini, M, Capitani, G, Glockshuber, R. | | Deposit date: | 2012-11-02 | | Release date: | 2013-05-29 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | (4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering.
Chembiochem, 14, 2013
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4LLB
 | | Crystal Structure of MOZ double PHD finger histone H3K14ac complex | | Descriptor: | Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION | | Authors: | Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. | | Deposit date: | 2013-07-09 | | Release date: | 2013-10-16 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
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4LKA
 | | Crystal Structure of MOZ double PHD finger histone H3K9ac complex | | Descriptor: | Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION | | Authors: | Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. | | Deposit date: | 2013-07-07 | | Release date: | 2013-10-16 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
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1Z2L
 | | Crystal structure of Allantoate-amidohydrolase from E.coli K12 in complex with substrate Allantoate | | Descriptor: | ALLANTOATE ION, Allantoate amidohydrolase, SULFATE ION, ... | | Authors: | Agarwal, R, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2005-03-08 | | Release date: | 2005-03-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural analysis of a ternary complex of allantoate amidohydrolase from Escherichia coli reveals its mechanics.
J.Mol.Biol., 368, 2007
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4H1M
 | | Crystal structure of PYK2 with the indole 10c | | Descriptor: | 7-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)-N-(propan-2-yl)-1H-indole-2-carboxamide, Protein-tyrosine kinase 2-beta | | Authors: | Han, S. | | Deposit date: | 2012-09-10 | | Release date: | 2012-11-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
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3R9A
 | | Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Peroxisomal targeting signal 1 receptor, Serine--pyruvate aminotransferase | | Authors: | Fodor, K, Wilmanns, M. | | Deposit date: | 2011-03-25 | | Release date: | 2011-05-11 | | Last modified: | 2012-05-02 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Molecular requirements for peroxisomal targeting of alanine-glyoxylate aminotransferase as an essential determinant in primary hyperoxaluria type 1
Plos Biol., 10, 2012
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4HE2
 | | Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ... | | Authors: | Shi, R, Zhu, D.W, Lin, S.X. | | Deposit date: | 2012-10-03 | | Release date: | 2013-10-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
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3RP8
 | | Crystal Structure of Klebsiella pneumoniae R204Q HpxO complexed with FAD | | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase | | Authors: | Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E. | | Deposit date: | 2011-04-26 | | Release date: | 2012-05-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.968 Å) | | Cite: | Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
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4HE1
 | | Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with fructose-6-phosphate and phosphate | | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ... | | Authors: | Shi, R, Zhu, D.W, Lin, S.X. | | Deposit date: | 2012-10-03 | | Release date: | 2013-10-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
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4LMX
 | | Light harvesting complex PE555 from the cryptophyte Hemiselmis andersenii CCMP644 | | Descriptor: | 15,16-DIHYDROBILIVERDIN, PHYCOERYTHROBILIN, cryptophyte phycoerythrin (alpha-1 chain), ... | | Authors: | Harrop, S.J, Wilk, K.E, Curmi, P.M.G. | | Deposit date: | 2013-07-11 | | Release date: | 2014-06-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Single-residue insertion switches the quaternary structure and exciton states of cryptophyte light-harvesting proteins.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4LDC
 | | Crystal Structure of DOC2B C2B domain | | Descriptor: | CALCIUM ION, CITRATE ANION, Double C2-like domain-containing protein beta | | Authors: | Giladi, M, Almagor, L, Hirsch, J.A. | | Deposit date: | 2013-06-24 | | Release date: | 2013-09-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.264 Å) | | Cite: | The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis.
J.Mol.Biol., 425, 2013
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4LCV
 | | Crystal Structure of DOC2B C2A domain | | Descriptor: | BETA-MERCAPTOETHANOL, CALCIUM ION, CITRATE ANION, ... | | Authors: | Giladi, M, Almagor, L, Hirsch, J.A. | | Deposit date: | 2013-06-23 | | Release date: | 2013-09-11 | | Last modified: | 2013-11-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis.
J.Mol.Biol., 425, 2013
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