PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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5KFR	Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 20 mM Mn2+ for 600s Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*(AS))-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KG4	Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Mg2+ for 60s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
2H6M	An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors Descriptor: N-ACETYL-LEUCYL-ALANYL-ALANYL-(N,N-DIMETHYL)-GLUTAMINE-(1,4-DIOXO-3,4-DIHYDRO-1H-PHTHALAZIN-2-YL)METHYLKETONE INHIBITOR, N-[(BENZYLOXY)CARBONYL]-L-ALANINE, Picornain 3C Authors: Yin, J, Cherney, M.M, Bergmann, E.M, James, M.N. Deposit date: 2006-05-31 Release date: 2006-08-08 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors. J.Mol.Biol., 361, 2006
1POV	ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION Descriptor: MYRISTIC ACID, POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), SPHINGOSINE Authors: Basavappa, R, Filman, D.J, Hogle, J.M. Deposit date: 1995-08-10 Release date: 1995-12-07 Last modified: 2023-04-19 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution. Protein Sci., 3, 1994
3NFQ	Crystal structure of the conserved central domain of yeast Spn1/Iws1 Descriptor: Transcription factor IWS1 Authors: Stargell, L.A, Luger, K. Deposit date: 2010-06-10 Release date: 2010-10-13 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif. J.Mol.Biol., 404, 2010
6FFA	FMDV Leader protease bound to substrate ISG15 Descriptor: GLYCEROL, Lbpro, SULFATE ION, ... Authors: Swatek, K.N, Pruneda, J.N, Komander, D. Deposit date: 2018-01-05 Release date: 2018-02-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8AG4	Vaccinia C16 protein bound to Ku70/Ku80 Descriptor: Protein C10, X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6 Authors: Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O. Deposit date: 2022-07-19 Release date: 2022-11-09 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (2.46 Å) Cite: Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus. Nat Commun, 13, 2022
8AG5	Vaccinia C16 protein bound to Ku70/Ku80 Descriptor: Ku70-Xrcc6, Protein C10, X-ray repair cross-complementing protein 5 Authors: Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O. Deposit date: 2022-07-19 Release date: 2022-11-09 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.47 Å) Cite: Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus. Nat Commun, 13, 2022
4BPU	Crystal structure of human primase in heterodimeric form, comprising PriS and truncated PriL lacking the C-terminal Fe-S domain. Descriptor: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, GLYCEROL, ... Authors: Kilkenny, M.L, Perera, R.L, Pellegrini, L. Deposit date: 2013-05-28 Release date: 2013-09-25 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering Proc.Natl.Acad.Sci.USA, 110, 2013
5HDA	Crystal Structure of the BS69 coiled coil-MYND domains bound to an EBNA2 PXLXP motif Descriptor: Epstein-Barr nuclear antigen 2, ZINC ION, Zinc finger MYND domain-containing protein 11 Authors: Song, J, Harter, M. Deposit date: 2016-01-05 Release date: 2016-01-20 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.3899 Å) Cite: BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2. Plos Pathog., 12, 2016
4BPW	Crystal structure of human primase bound to UTP Descriptor: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, MAGNESIUM ION, ... Authors: Kilkenny, M.L, Perera, R.L, Pellegrini, L. Deposit date: 2013-05-28 Release date: 2013-09-25 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.003 Å) Cite: Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering Proc.Natl.Acad.Sci.USA, 110, 2013
1S7O	Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes Descriptor: Hypothetical UPF0122 protein SPy1201/SpyM3_0842/SPs1042/spyM18_1152 Authors: Oganesyan, V, Pufan, R, DeGiovanni, A, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) Deposit date: 2004-01-29 Release date: 2004-06-29 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes. Acta Crystallogr.,Sect.D, 60, 2004
2LOX	NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and Rad2 Descriptor: DNA repair protein RAD2, RNA polymerase II transcription factor B subunit 1 Authors: Lafrance-Vanasse, J, Legault, P, Omichinski, J. Deposit date: 2012-01-27 Release date: 2012-02-15 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural and functional characterization of interactions involving the Tfb1 subunit of TFIIH and the NER factor Rad2. Nucleic Acids Res., 40, 2012
2DB9	Solution structure of the plus-3 domain of human KIAA0252 protein Descriptor: Paf1/RNA polymerase II complex component Authors: Yoneyama, M, Kigawa, T, Tochio, N, Nameki, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-12-15 Release date: 2006-06-15 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the plus-3 domain of human KIAA0252 protein To be Published
2QUS	Hammerhead Ribozyme G12A mutant pre-cleavage Descriptor: Hammerhead ribozyme, MAGNESIUM ION Authors: Chi, Y.I, Scott, W.G, Kim, S.H. Deposit date: 2007-08-06 Release date: 2008-07-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Capturing hammerhead ribozyme structures in action by modulating general base catalysis. Plos Biol., 6, 2008
3GJW	PARP complexed with A968427 Descriptor: 7-(pyrrolidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one, Poly [ADP-ribose] polymerase 1 Authors: Park, C.H. Deposit date: 2009-03-09 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1) Bioorg.Med.Chem.Lett., 19, 2009
7UWN	Structure of the IL-17A-IL-17RA-IL-17RC ternary complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... Authors: Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. Deposit date: 2022-05-03 Release date: 2022-07-27 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
1EAH	PV2L COMPLEXED WITH ANTIVIRAL AGENT SCH48973 Descriptor: 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, POLIOVIRUS TYPE 2 COAT PROTEINS VP1 TO VP4 Authors: Lentz, K, Arnold, E. Deposit date: 1997-07-22 Release date: 1998-09-16 Last modified: 2023-04-19 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of poliovirus type 2 Lansing complexed with antiviral agent SCH48973: comparison of the structural and biological properties of three poliovirus serotypes. Structure, 5, 1997
2M14	NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and Rad4 Descriptor: DNA repair protein RAD4, RNA polymerase II transcription factor B subunit 1 Authors: Lafrance-Vanasse, J, Arseneault, G, Cappadocia, L, Legault, P, Omichinski, J.G. Deposit date: 2012-11-16 Release date: 2013-01-23 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER. Nucleic Acids Res., 41, 2013
6ZUZ	TFIIS N-terminal domain (TND) from human Elongin-A Descriptor: Elongin-A Authors: Veverka, V. Deposit date: 2020-07-23 Release date: 2021-12-01 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
6Z4X	Structure of the CAK complex form Chaetomium thermophilum bound to ATP-gamma-S Descriptor: CHLORIDE ION, CYCLIN domain-containing protein, MAGNESIUM ION, ... Authors: Peissert, S, Kuper, J, Kisker, C. Deposit date: 2020-05-26 Release date: 2020-12-09 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Structural basis for CDK7 activation by MAT1 and Cyclin H. Proc.Natl.Acad.Sci.USA, 117, 2020
2K2U	NMR Structure of the complex between Tfb1 subunit of TFIIH and the activation domain of VP16 Descriptor: Alpha trans-inducing protein, RNA polymerase II transcription factor B subunit 1 Authors: Langlois, C, Mas, C, Di Lello, P, Miller Jenkins, P.M, Legault, J, Omichinski, J.G. Deposit date: 2008-04-11 Release date: 2008-08-12 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53. J.Am.Chem.Soc., 130, 2008
5JW9	The Crystal Structure of ELL2 Oclludin Domain and AFF4 peptide Descriptor: AF4/FMR2 family member 4, RNA polymerase II elongation factor ELL2 Authors: Qi, S, Hurley, J.H. Deposit date: 2016-05-11 Release date: 2017-02-08 Method: X-RAY DIFFRACTION (2.003 Å) Cite: Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription. Nat Commun, 8, 2017
2EYQ	Crystal structure of Escherichia coli transcription-repair coupling factor Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Transcription-repair coupling factor Authors: Deaconescu, A.M, Darst, S.A. Deposit date: 2005-11-09 Release date: 2006-02-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis for bacterial transcription-coupled DNA repair. Cell(Cambridge,Mass.), 124, 2006
1TFB	NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES Descriptor: TFIIB Authors: Bagby, S, Ikura, M. Deposit date: 1996-11-14 Release date: 1997-03-12 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Human general transcription factor TFIIB: conformational variability and interaction with VP16 activation domain. Biochemistry, 37, 1998

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