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7U0O
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BU of 7u0o by Molmil
Crystal structure of an enoyl-[acyl-carrier-protein] reductase InhA from Mycobacterium fortuitum bound to NAD and NITD-916
Descriptor: 6-[(4,4-dimethylcyclohexyl)methyl]-4-hydroxy-3-phenylpyridin-2(1H)-one, CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-02-18
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:In Vitro and In Vivo Efficacy of NITD-916 against Mycobacterium fortuitum.
Antimicrob.Agents Chemother., 67, 2023
8BM6
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Hairpin adopted by oligonucleotide A36 found in the promoter of AUTS2 gene
Descriptor: A36
Authors:Novotny, A.
Deposit date:2022-11-10
Release date:2023-02-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene.
Nucleic Acids Res., 51, 2023
8BM7
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BU of 8bm7 by Molmil
Hairpin adopted by oligonucleotide A38 found in the promoter of AUTS2 gene.
Descriptor: A38
Authors:Novotny, A.
Deposit date:2022-11-10
Release date:2023-02-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene.
Nucleic Acids Res., 51, 2023
8BM4
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BU of 8bm4 by Molmil
Hairpin adopted by modified oligonucleotide A32_mod found in the promoter of AUTS2 gene.
Descriptor: A32_mod
Authors:Novotny, A.
Deposit date:2022-11-10
Release date:2023-02-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene.
Nucleic Acids Res., 51, 2023
8BXR
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BU of 8bxr by Molmil
Titin FnIII-domain I109-I111 (I/A4-A/A6) from the MIR region
Descriptor: 1,2-ETHANEDIOL, Titin
Authors:Mayans, O, Fleming, J.R, Williams, R.
Deposit date:2022-12-09
Release date:2023-02-15
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
8DD7
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BU of 8dd7 by Molmil
The Cryo-EM structure of Drosophila Cryptochrome in complex with Timeless
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Methylated-DNA--protein-cysteine methyltransferase,Cryptochrome-1 fusion, Protein timeless,Methylated-DNA--protein-cysteine methyltransferase fusion
Authors:Feng, S, Lin, C, DeOliveira, C.C, Crane, B.R.
Deposit date:2022-06-17
Release date:2023-02-15
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryptochrome-Timeless structure reveals circadian clock timing mechanisms.
Nature, 617, 2023
8BVO
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BU of 8bvo by Molmil
Titin I110-I111 FnIII tandem from the MIR region (I/A5-I/A6)
Descriptor: Titin
Authors:Mayans, O, Fleming, J.R, Williams, R.
Deposit date:2022-12-05
Release date:2023-02-15
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
8BW6
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BU of 8bw6 by Molmil
Titin FnIII-domain I110 (I/A6) from the MIR region
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Mayans, O, Fleming, J.R.
Deposit date:2022-12-06
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
7XH2
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BU of 7xh2 by Molmil
Dihydrofolate Reductase-like Protein SacH in safracin biosynthesis
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized protein sfcH
Authors:Ma, X, Shao, N, Ma, M, Tang, G.
Deposit date:2022-04-07
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis.
Acta Pharm Sin B, 13, 2023
7XH4
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BU of 7xh4 by Molmil
Dihydrofolate Reductase-like Protein SacH in safracin biosynthesis complex with safracin A
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Safracin A, Uncharacterized protein sfcH
Authors:Ma, X, Shao, N, Zhang, Y, Yang, D, Ma, M, Tang, G.
Deposit date:2022-04-07
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis.
Acta Pharm Sin B, 13, 2023
8ERX
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BU of 8erx by Molmil
Structure of chimeric HLA-A*11:01-A*02:01 bound to HIV-1 RT peptide
Descriptor: Beta-2-microglobulin, HIV-1 RT, HLA-A*02:01
Authors:Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G.
Deposit date:2022-10-13
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules.
Front Immunol, 14, 2023
8ESH
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BU of 8esh by Molmil
Structure of chimeric HLA-A*02:01 bound to CMV peptide
Descriptor: Beta-2-microglobulin, CMV peptide, HLA-A*02:01
Authors:Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G.
Deposit date:2022-10-14
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules.
Front Immunol, 14, 2023
7T9C
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BU of 7t9c by Molmil
Crystal structure of dehaloperoxidase B in complex with thymol
Descriptor: 5-METHYL-2-(1-METHYLETHYL)PHENOL, Dehaloperoxidase B, GLYCEROL, ...
Authors:de Serrano, V.S, Ghiladi, R.A, Malewschik, T, Yun, D.
Deposit date:2021-12-18
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The Multifunctional Globin Dehaloperoxidase as a Biocatalyst in the Oxidation of Monoterpenes
To Be Published
8BVM
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BU of 8bvm by Molmil
Cryo-EM structure of Hfq-Crc-rbsB translation repression complex
Descriptor: Catabolite repression control protein, RNA-binding protein Hfq, rbsB mRNA
Authors:Dendooven, T, Luisi, B.F.
Deposit date:2022-12-04
Release date:2023-01-25
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Translational regulation by Hfq-Crc assemblies emerges from polymorphic ribonucleoprotein folding.
Embo J., 42, 2023
8BVJ
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BU of 8bvj by Molmil
Hfq-Crc-estA translation repression complex
Descriptor: Catabolite repression control protein, RNA-binding protein Hfq, estA mRNA
Authors:Dendooven, T, Luisi, B.F.
Deposit date:2022-12-04
Release date:2023-01-25
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Translational regulation by Hfq-Crc assemblies emerges from polymorphic ribonucleoprotein folding.
Embo J., 42, 2023
7YKW
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BU of 7ykw by Molmil
Structure of hIAPP fibril at 3.6 Angstroms resolution
Descriptor: Islet amyloid polypeptide
Authors:Li, D, Zhang, X, Wang, Y, Zhu, P.
Deposit date:2022-07-25
Release date:2023-01-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
8H8C
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BU of 8h8c by Molmil
Type VI secretion system effector RhsP in its post-autoproteolysis and dimeric form
Descriptor: C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein
Authors:Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H.
Deposit date:2022-10-22
Release date:2023-01-18
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP.
Cell Rep, 41, 2022
8H8B
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BU of 8h8b by Molmil
Type VI secretion system effector RhsP in its pre-autoproteolysis and monomeric form
Descriptor: Putative Rhs-family protein
Authors:Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H.
Deposit date:2022-10-22
Release date:2023-01-18
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP.
Cell Rep, 41, 2022
8H8A
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BU of 8h8a by Molmil
Type VI secretion system effector RhsP in its post-autoproteolysis and monomeric form
Descriptor: C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein
Authors:Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H.
Deposit date:2022-10-22
Release date:2023-01-18
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP.
Cell Rep, 41, 2022
7QOX
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BU of 7qox by Molmil
Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
Authors:Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J.
Deposit date:2021-12-29
Release date:2023-01-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J Thromb Haemost, 17, 2019
7QOT
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BU of 7qot by Molmil
Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIa heavy chain, Kininogen-1 light chain, ...
Authors:Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J.
Deposit date:2021-12-28
Release date:2023-01-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J Thromb Haemost, 17, 2019
7Z3S
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BU of 7z3s by Molmil
CRYSTAL STRUCTURE of PheF from Geobacillus stearothermophilus
Descriptor: Acetaldehyde dehydrogenase, PHOSPHATE ION
Authors:Driller, R, Haack, M, Brueck, T, Loll, B.
Deposit date:2022-03-02
Release date:2023-01-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:CRYSTAL STRUCTURE OF THE P1 trifluoroethylglycine (TfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
To Be Published
7SJU
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BU of 7sju by Molmil
Myocilin OLF mutant T293K
Descriptor: CALCIUM ION, GLYCEROL, Myocilin, ...
Authors:Scelsi, H.S, Barlow, B.M, Lieberman, R.L.
Deposit date:2021-10-19
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.391 Å)
Cite:Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability.
Dis Model Mech, 16, 2023
7SIJ
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BU of 7sij by Molmil
Myocilin OLF mutant E352K
Descriptor: CALCIUM ION, GLYCEROL, Myocilin, ...
Authors:Scelsi, H.S, Barlow, B.M, Lieberman, R.L.
Deposit date:2021-10-14
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability.
Dis Model Mech, 16, 2023
7SJV
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BU of 7sjv by Molmil
Myocilin OLF mutant T353I
Descriptor: CALCIUM ION, Myocilin, C-terminal fragment, ...
Authors:Scelsi, H.S, Barlow, B.M, Lieberman, R.L.
Deposit date:2021-10-19
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability.
Dis Model Mech, 16, 2023

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數據於2024-09-18公開中

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