4MI4
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![BU of 4mi4 by Molmil](/molmil-images/mine/4mi4) | Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with spermine | Descriptor: | SPERMINE, Spermidine n1-acetyltransferase | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-30 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.848 Å) | Cite: | A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. J.Mol.Biol., 427, 2015
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5XOQ
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6OKF
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![BU of 6okf by Molmil](/molmil-images/mine/6okf) | Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and C16-crypto Acyl Carrier Protein, AcpP | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, N-[2-(dodecanoylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... | Authors: | Mindrebo, J.T, Kim, W.E, Bartholow, T.G, Chen, A, Davis, T.D, La Clair, J, Burkart, M.D, Noel, J.P. | Deposit date: | 2019-04-12 | Release date: | 2020-04-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Gating mechanism of elongating beta-ketoacyl-ACP synthases. Nat Commun, 11, 2020
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4MJ8
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![BU of 4mj8 by Molmil](/molmil-images/mine/4mj8) | Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with polyamine | Descriptor: | ETHANOL, SPERMINE, Spermidine n1-acetyltransferase | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-03 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with polyamine To be Published
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4MM1
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![BU of 4mm1 by Molmil](/molmil-images/mine/4mm1) | GGGPS from Methanothermobacter thermautotrophicus | Descriptor: | Geranylgeranylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE, TRIETHYLENE GLYCOL | Authors: | Rajendran, C, Peterhoff, D, Beer, B, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P. | Deposit date: | 2013-09-07 | Release date: | 2014-06-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8004 Å) | Cite: | A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization. Mol.Microbiol., 92, 2014
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1J3J
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![BU of 1j3j by Molmil](/molmil-images/mine/1j3j) | Double mutant (C59R+S108N) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | Authors: | Yuvaniyama, J, Chitnumsub, P, Kamchonwongpaisan, S, Vanichtanankul, J, Sirawaraporn, W, Taylor, P, Walkinshaw, M, Yuthavong, Y. | Deposit date: | 2003-02-03 | Release date: | 2003-05-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Insights into antifolate resistance from malarial DHFR-TS structures. NAT.STRUCT.BIOL., 10, 2003
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1RZZ
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![BU of 1rzz by Molmil](/molmil-images/mine/1rzz) | PHOTOSYNTHETIC REACTION CENTER DOUBLE MUTANT FROM RHODOBACTER SPHAEROIDES WITH ASP L213 REPLACED WITH ASN AND ARG M233 REPLACED WITH CYS IN THE CHARGE-NEUTRAL DQAQB STATE (TETRAGONAL FORM) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ... | Authors: | Xu, Q, Axelrod, H.L, Abresch, E.C, Paddock, M.L, Okamura, M.Y, Feher, G. | Deposit date: | 2003-12-29 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-Ray Structure Determination of Three Mutants of the Bacterial Photosynthetic Reaction Centers from Rb. sphaeroides; Altered Proton Transfer Pathways. STRUCTURE, 12, 2004
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6ARE
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![BU of 6are by Molmil](/molmil-images/mine/6are) | Aspergillus fumigatus Cytosolic Thiolase in complex with two tetrahedral reaction intermediates and ammonium ions | Descriptor: | ACETATE ION, ACETYL COENZYME *A, AMMONIUM ION, ... | Authors: | Marshall, A.C, Bond, C.S, Bruning, J.B. | Deposit date: | 2017-08-22 | Release date: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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6OS3
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![BU of 6os3 by Molmil](/molmil-images/mine/6os3) | Crystal structure of native CymD prenyltransferase | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CymD prenyltransferase | Authors: | Roose, B.W, Christianson, D.W. | Deposit date: | 2019-05-01 | Release date: | 2019-07-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD. Biochemistry, 58, 2019
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1S2T
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![BU of 1s2t by Molmil](/molmil-images/mine/1s2t) | Crystal Structure Of Apo Phosphoenolpyruvate Mutase | Descriptor: | Phosphoenolpyruvate phosphomutase | Authors: | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | Deposit date: | 2004-01-11 | Release date: | 2004-05-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conformational Flexibility of PEP Mutase Biochemistry, 43, 2004
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5XW3
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5XWB
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![BU of 5xwb by Molmil](/molmil-images/mine/5xwb) | Crystal Structure of 5-Enolpyruvulshikimate-3-phosphate Synthase from a Psychrophilic Bacterium, Colwellia psychrerythraea | Descriptor: | 3-phosphoshikimate 1-carboxyvinyltransferase | Authors: | Lee, J.H, Kim, H.J, Choi, J.M, Kim, D.-W, Seo, Y.-S. | Deposit date: | 2017-06-29 | Release date: | 2017-09-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of 5-enolpyruvylshikimate-3-phosphate synthase from a psychrophilic bacterium, Colwellia psychrerythraea 34H. Biochem. Biophys. Res. Commun., 492, 2017
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2Z11
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![BU of 2z11 by Molmil](/molmil-images/mine/2z11) | Crystal structure of putative acetyltransferase | Descriptor: | Ribosomal-protein-alanine acetyltransferase | Authors: | Murayama, K, Kato-Murayama, M, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-07 | Release date: | 2007-11-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of putative acetyltransferase To be Published
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1S60
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![BU of 1s60 by Molmil](/molmil-images/mine/1s60) | Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and N-terminal His(6)-tag (crystal form 2) | Descriptor: | COENZYME A, SULFATE ION, aminoglycoside 6'-N-acetyltransferase | Authors: | Vetting, M.W, Magnet, S, Nieves, E, Roderick, S.L, Blanchard, J.S. | Deposit date: | 2004-01-22 | Release date: | 2004-05-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones Chem.Biol., 11, 2004
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1SIY
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![BU of 1siy by Molmil](/molmil-images/mine/1siy) | NMR structure of mung bean non-specific lipid transfer protein 1 | Descriptor: | Nonspecific lipid-transfer protein 1 | Authors: | Lin, K.F, Liu, Y.N, Hsu, S.T.D, Samuel, D, Cheng, C.S, Bonvin, A.M.J.J, Lyu, P.C. | Deposit date: | 2004-03-02 | Release date: | 2005-04-05 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Characterization and Structural Analyses of Nonspecific Lipid Transfer Protein 1 from Mung Bean Biochemistry, 44, 2005
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1IXM
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![BU of 1ixm by Molmil](/molmil-images/mine/1ixm) | CRYSTAL STRUCTURE OF SPOOB FROM BACILLUS SUBTILIS | Descriptor: | PROTEIN (SPORULATION RESPONSE REGULATORY PROTEIN) | Authors: | Varughese, K.I. | Deposit date: | 1998-11-06 | Release date: | 1998-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Formation of a novel four-helix bundle and molecular recognition sites by dimerization of a response regulator phosphotransferase. Mol.Cell, 2, 1998
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1SD0
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![BU of 1sd0 by Molmil](/molmil-images/mine/1sd0) | Structure of arginine kinase C271A mutant | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ... | Authors: | Gattis, J.L, Ruben, E, Fenley, M.O, Ellington, W.R, Chapman, M.S. | Deposit date: | 2004-02-12 | Release date: | 2004-07-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The active site cysteine of arginine kinase: structural and functional analysis of partially active mutants Biochemistry, 43, 2004
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1RY5
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![BU of 1ry5 by Molmil](/molmil-images/mine/1ry5) | PHOTOSYNTHETIC REACTION CENTER MUTANT FROM RHODOBACTER SPHAEROIDES WITH ASP L213 REPLACED WITH ASN | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | Authors: | Xu, Q, Axelrod, H.L, Abresch, E.C, Paddock, M.L, Okamura, M.Y, Feher, G. | Deposit date: | 2003-12-19 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-Ray Structure Determination of Three Mutants of the Bacterial Photosynthetic Reaction Centers from Rb. sphaeroides; Altered Proton Transfer Pathways. STRUCTURE, 12, 2004
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6BFF
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6OTX
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![BU of 6otx by Molmil](/molmil-images/mine/6otx) | Crystallographic Structure of (HbII-HbIII)-O2 from Lucina pectinata at pH 7.0 | Descriptor: | Hemoglobin II, Hemoglobin III, OXYGEN MOLECULE, ... | Authors: | Marchany-Rivera, D, Smith, C.A, Rodriguez-Perez, J.D, Lopez-Garriga, J. | Deposit date: | 2019-05-03 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.539 Å) | Cite: | Lucina pectinata oxyhemoglobin (II-III) heterodimer pH susceptibility. J.Inorg.Biochem., 207, 2020
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5XYJ
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2Z10
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![BU of 2z10 by Molmil](/molmil-images/mine/2z10) | Crystal structure of putative acetyltransferase | Descriptor: | Ribosomal-protein-alanine acetyltransferase | Authors: | Murayama, K, Kato-Murayama, M, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-07 | Release date: | 2007-11-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Genetic Encoding of 3-Iodo-l-Tyrosine in Escherichia coli for Single-Wavelength Anomalous Dispersion Phasing in Protein Crystallography Structure, 17, 2009
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6AO7
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6AOH
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![BU of 6aoh by Molmil](/molmil-images/mine/6aoh) | Crystal structure of Toxoplasma gondii TS-DHFR complexed with NADPH, dUMP, PDDF, and 5-(4-(3-(2-methoxypyrimidin-5-yl)phenyl)piperazin-1-yl)pyrimidine-2,4-diamine (TRC-2533) | Descriptor: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-{4-[3-(2-methoxypyrimidin-5-yl)phenyl]piperazin-1-yl}pyrimidine-2,4-diamine, ... | Authors: | Thomas, S.B, Li, Y, Chen, Z, Lu, H. | Deposit date: | 2017-08-16 | Release date: | 2018-08-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Identification of selective, brain penetrant Toxoplasma gondii dihydrofolate reductase inhibitors for the treatment of toxoplasmosis To Be Published
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4KVO
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