8ZME
 
 | | Protease-activated receptor-2 (PAR2)/miniG13 complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Proteinase-activated receptor 2, ... | | Authors: | He, Y, Zhu, X. | | Deposit date: | 2024-05-23 | | Release date: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Protease-activated receptor-2 (PAR2)/miniG13 complex
To Be Published
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6KZA
 | | Crystal structure of the complex of the interaction domains of E. coli DnaB helicase and DnaC helicase loader | | Descriptor: | DNA replication protein DnaC, Replicative DNA helicase | | Authors: | Nagata, K, Okada, A, Ohtsuka, J, Ohkuri, T, Akama, Y, Sakiyama, Y, Miyazaki, E, Horita, S, Katayama, T, Ueda, T, Tanokura, M. | | Deposit date: | 2019-09-23 | | Release date: | 2019-11-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of the complex of the interaction domains of Escherichia coli DnaB helicase and DnaC helicase loader: structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding.
J.Biochem., 167, 2020
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8ZML
 | | Structure of TNIK with inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2-[5-(4-fluorophenyl)-3-propan-2-yl-imidazol-4-yl]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-1~{H}-imidazole-4-carboxamide, MAGNESIUM ION, ... | | Authors: | Fan, Y. | | Deposit date: | 2024-05-23 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.489 Å) | | Cite: | Structure of TNIK with inhibitor
To Be Published
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5JLJ
 | | Crystal Structure of KPT8602 in complex with CRM1-Ran-RanBP1 | | Descriptor: | (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, CHLORIDE ION, Exportin-1, ... | | Authors: | Fung, H.Y, Chook, Y.M. | | Deposit date: | 2016-04-27 | | Release date: | 2016-06-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies.
Leukemia, 30, 2016
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8ZNV
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1KRU
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8ZRG
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5JMZ
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2I29
 | | Crystal structure of NAD kinase 1 from Listeria monocytogenes | | Descriptor: | CITRIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable inorganic polyphosphate/ATP-NAD kinase 1 | | Authors: | Poncet-Montange, G, Assairi, L, Arold, S, Pochet, S, Labesse, G. | | Deposit date: | 2006-08-16 | | Release date: | 2007-08-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
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8ZOM
 | | Cryo-EM structure of pyraclostrobin-bound Arachis hypogaea bc1 complex | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | | Authors: | Cui, G.R, Wang, Y.X, Yang, G.F. | | Deposit date: | 2024-05-28 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | Cryo-EM structure of pyraclostrobin-bound Arachis hypogaea bc1 complex
To Be Published
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2VI0
 | | Lichenase CtLic26 in complex with a thio-oligosaccharide | | Descriptor: | 4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside, Endoglucanase H, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Money, V.A, Ducros, V.M, Davies, G.J. | | Deposit date: | 2007-11-26 | | Release date: | 2009-03-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Probing the beta-1,3:1,4 glucanase, CtLic26A, with a thio-oligosaccharide and enzyme variants.
Org. Biomol. Chem., 6, 2008
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6L0S
 | | Crystal Structure of the O-Phosphoserine Sulfhydrylase from Aeropyrum pernix Complexed with L-Cysteine | | Descriptor: | (2R)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-propanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Protein CysO | | Authors: | Nakabayashi, M, Takeda, E, Ishikawa, K, Nakamura, T. | | Deposit date: | 2019-09-26 | | Release date: | 2020-09-23 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Identification of amino acid residues important for recognition of O-phospho-l-serine substrates by cysteine synthase.
J.Biosci.Bioeng., 131, 2021
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8ZQ7
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2I2Q
 | | Fission Yeast cofilin | | Descriptor: | 1,2-ETHANEDIOL, Cofilin, LAURYL DIMETHYLAMINE-N-OXIDE, ... | | Authors: | Andrianantoandro, E, Pollard, T.D. | | Deposit date: | 2006-08-16 | | Release date: | 2006-10-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Mechanism of Actin Filament Turnover by Severing and Nucleation at Different Concentrations of ADF/Cofilin.
Mol.Cell, 24, 2006
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8ZVZ
 | | Cryo-EM strcuture of Prostaglandin D2 Receptor DP1 activated by BW245C | | Descriptor: | 7-{(4S)-3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxoimidazolidin-4-yl}heptanoic acid, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Xu, J, Xu, Y, Wu, C, Xu, H.E. | | Deposit date: | 2024-06-12 | | Release date: | 2025-05-28 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.35 Å) | | Cite: | Molecular basis for ligand recognition and receptor activation of the prostaglandin D2 receptor DP1.
Proc.Natl.Acad.Sci.USA, 122, 2025
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6L1H
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9AZN
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8ZO0
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2IA7
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8ZNM
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8ZR2
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9AZS
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2I3C
 | | Crystal Structure of an Aspartoacylase from Homo Sapiens | | Descriptor: | Aspartoacylase, PHOSPHATE ION, ZINC ION | | Authors: | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-08-17 | | Release date: | 2006-08-29 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2I3R
 | | Engineered catalytic domain of protein tyrosine phosphatase HPTPbeta | | Descriptor: | CHLORIDE ION, Receptor-type tyrosine-protein phosphatase beta | | Authors: | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | | Deposit date: | 2006-08-20 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
Acta Crystallogr.,Sect.D, 62, 2006
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8ZNQ
 | | Solution structure of the complex of naphthyridine-azaquinolone and an RNA with ACG/AUA motif | | Descriptor: | N~3~-{3-[(7-METHYL-1,8-NAPHTHYRIDIN-2-YL)AMINO]-3-OXOPROPYL}-N~1~-[(7-OXO-7,8-DIHYDRO-1,8-NAPHTHYRIDIN-2-YL)METHYL]-BET A-ALANINAMIDE, RNA (30-MER) | | Authors: | Fujiwara, A, Chen, Q, Nakatani, K, Murata, A, Kawai, G. | | Deposit date: | 2024-05-27 | | Release date: | 2025-06-04 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the complex of naphthyridine-azaquinolone and an RNA with ACG/AUA motif
To Be Published
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