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3NEP
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BU of 3nep by Molmil
1.55A resolution structure of malate dehydrogenase from Salinibacter ruber
Descriptor: Malate dehydrogenase
Authors:Coquelle, N, Madern, D.
Deposit date:2010-06-09
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Gradual adaptive changes of a protein facing high salt concentrations.
J.Mol.Biol., 404, 2010
4I1I
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BU of 4i1i by Molmil
Crystal structure of a putative Cytosolic malate dehydrogenase from Leishmania major Friedlin in complex with NAD
Descriptor: 1,2-ETHANEDIOL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-11-21
Release date:2012-12-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a putative Cytosolic malate dehydrogenase from Leishmania major Friedlin in complex with NAD
TO BE PUBLISHED
4UUL
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BU of 4uul by Molmil
Apo trichomonas vaginalis lactate dehydrogenase L91R
Descriptor: L-LACTATE DEHYDROGENASE
Authors:Steindel, P.A, Chen, E.H, L Theobald, D.
Deposit date:2014-07-29
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases.
Protein Sci., 25, 2016
1T2E
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BU of 1t2e by Molmil
Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase, ...
Authors:Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G.
Deposit date:2004-04-21
Release date:2004-05-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T26
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BU of 1t26 by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with NADH and 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-HYDROXY-1,2,5-THIADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase
Authors:Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G.
Deposit date:2004-04-20
Release date:2004-05-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
6MVA
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BU of 6mva by Molmil
LDHA structure in complex with inhibitor 14
Descriptor: (6R)-6-(3-aminophenyl)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eigenbrot, C.E, Ultsch, M, Wei, B.
Deposit date:2018-10-24
Release date:2019-10-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structure-based Optimization of Potent, Cell-Active Hydroxylactam Inhibitors of Lactate Dehydrogenase
To Be Published
4UUM
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BU of 4uum by Molmil
Apo trichomonas vaginalis lactate dehydrogenase
Descriptor: L-LACTATE DEHYDROGENASE
Authors:Steindel, P.A, Chen, E.H, Theobald, D.L.
Deposit date:2014-07-29
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.368 Å)
Cite:Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases.
Protein Sci., 25, 2016
4UUN
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BU of 4uun by Molmil
Trichomonas vaginalis lactate dehydrogenase in complex with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-LACTATE DEHYDROGENASE
Authors:Steindel, P.A, Chen, E.H, Theobald, D.L.
Deposit date:2014-07-29
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases.
Protein Sci., 25, 2016
7MDH
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BU of 7mdh by Molmil
STRUCTURAL BASIS FOR LIGHT ACITVATION OF A CHLOROPLAST ENZYME. THE STRUCTURE OF SORGHUM NADP-MALATE DEHYDROGENASE IN ITS OXIDIZED FORM
Descriptor: PROTEIN (MALATE DEHYDROGENASE), ZINC ION
Authors:Johansson, K, Ramaswamy, S, Saarinen, M, Lemaire-Chamley, M, Issakidis-Bourguet, E, Miginiac-Maslow, M, Eklund, H.
Deposit date:1999-02-16
Release date:1999-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for light activation of a chloroplast enzyme: the structure of sorghum NADP-malate dehydrogenase in its oxidized form.
Biochemistry, 38, 1999
7QOZ
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BU of 7qoz by Molmil
Crystal structure of NAD-bound glycosomal malate dehydrogenase from Trypanosoma cruzi
Descriptor: GLYCEROL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Sonani, R.R, Dubin, G.
Deposit date:2021-12-30
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of NAD-bound glycosomal malate dehydrogenase from Trypanosoma cruzi
To Be Published
7M2N
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BU of 7m2n by Molmil
Crystal structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15
Descriptor: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5-[(5'-{1-(4-carboxy-1,3-thiazol-2-yl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-3-yl}-2'-fluoro[1,1'-biphenyl]-4-yl)oxy]-1H-1,2,3-triazole-4-carboxylic acid, ...
Authors:Gumpena, R, Ding, J, Powell, D.A, Lowther, W.T.
Deposit date:2021-03-17
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria
ACS Medicinal Chemistry Letters, 12, 2021
1U5A
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BU of 1u5a by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 3,5-dihydroxy-2-naphthoic acid
Descriptor: 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase
Authors:Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L.
Deposit date:2004-07-27
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
7NAY
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BU of 7nay by Molmil
Crystal structure of lactate dehydrogenase from Selenomonas ruminantium with NADH.
Descriptor: 1,2-ETHANEDIOL, BORIC ACID, L-lactate dehydrogenase, ...
Authors:Bertrand, Q, Robin, A, Girard, E, Madern, D.
Deposit date:2021-01-25
Release date:2021-02-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases.
J.Struct.Biol., 215, 2023
7RM9
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BU of 7rm9 by Molmil
Human Malate Dehydrogenase I (MDHI)
Descriptor: MALONATE ION, Malate dehydrogenase, cytoplasmic
Authors:McCue, W, Finzel, B.C.
Deposit date:2021-07-27
Release date:2022-01-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Characterization of the Human Cytosolic Malate Dehydrogenase I.
Acs Omega, 7, 2022
7RRL
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BU of 7rrl by Molmil
Alternate Crystal Form of Human Malate Dehydrogenase I
Descriptor: Malate dehydrogenase, cytoplasmic
Authors:McCue, W, Finzel, B.C.
Deposit date:2021-08-09
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Studies to Enable Drug Discovery
Ph.D.Thesis,University of Minnesota, 2021
6OR9
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BU of 6or9 by Molmil
Structure of L-lactate dehydrogenase from Trichoplusia ni
Descriptor: L-lactate dehydrogenase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-04-29
Release date:2019-07-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of L-lactate dehydrogenase from Trichoplusia ni
to be published
6P6U
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BU of 6p6u by Molmil
Crystal Structure of Monoclinic Rabbit Muscle Lactate Dehydrogenase with Four Tetramers as the Asymmetric Unit
Descriptor: ADENOSINE MONOPHOSPHATE, L-lactate dehydrogenase A chain
Authors:McPherson, A.
Deposit date:2019-06-04
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Crystal Structure of Monoclinic Rabbit Muscle Lactate Dehydrogenase with Four Tetramers as the Asymmetric Unit
to be published
3VPH
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BU of 3vph by Molmil
L-lactate dehydrogenase from Thermus caldophilus GK24 complexed with oxamate, NADH and FBP
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, L-lactate dehydrogenase, ...
Authors:Arai, K, Ohno, T, Miyanaga, A, Fushinobu, S, Taguchi, H.
Deposit date:2012-03-01
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase.
J.Biol.Chem., 2014
3VPG
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BU of 3vpg by Molmil
L-lactate dehydrogenase from Thermus caldophilus GK24
Descriptor: GLYCEROL, L-lactate dehydrogenase
Authors:Arai, K, Ohno, T, Miyanaga, A, Fushinobu, S, Taguchi, H.
Deposit date:2012-03-01
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase.
J.Biol.Chem., 2014
3TL2
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BU of 3tl2 by Molmil
Crystal structure of Bacillus anthracis str. Ames malate dehydrogenase in closed conformation.
Descriptor: 1,2-ETHANEDIOL, Malate dehydrogenase, THIOCYANATE ION
Authors:Blus, B.J, Chruszcz, M, Tkaczuk, K.L, Osinski, T, Cymborowski, M, Kudritska, M, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-08-29
Release date:2011-09-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Bacillus anthracis str. Ames malate dehydrogenase in closed conformation.
TO BE PUBLISHED
6IHD
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BU of 6ihd by Molmil
Crystal structure of Malate dehydrogenase from Metallosphaera sedula
Descriptor: 2-ETHOXYETHANOL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Lee, D, Kim, K.J.
Deposit date:2018-09-29
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula
Biochem. Biophys. Res. Commun., 509, 2019
7X1L
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BU of 7x1l by Molmil
Malate dehydrogenase from Geobacillus stearothermophilus (gs-MDH) delta E311 mutant complexed with Nicotinamide Adenine Dinucleotide (NAD+)
Descriptor: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Shimozawa, Y, Himiyama, T, Nakamura, T, Nishiya, Y.
Deposit date:2022-02-24
Release date:2022-10-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Reducing substrate inhibition of malate dehydrogenase from Geobacillus stearothermophilus by C-terminal truncation.
Protein Eng.Des.Sel., 35, 2022
6IHE
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BU of 6ihe by Molmil
Crystal structure of Malate dehydrogenase from Metallosphaera sedula
Descriptor: 1,2-ETHANEDIOL, D-MALATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Lee, D, Kim, K.J.
Deposit date:2018-09-29
Release date:2019-02-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula
Biochem. Biophys. Res. Commun., 509, 2019
6ITK
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BU of 6itk by Molmil
Crystal structure of malate dehydrogenase from Corynebacterium glutamicum ATCC 13032 in complex with NAD and malate
Descriptor: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Seo, H, Kim, K.-J.
Deposit date:2018-11-23
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase.
Nat Commun, 11, 2020
6J9D
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BU of 6j9d by Molmil
Babesia microti lactate dehydrogenase R99A (BmLDHR99A)
Descriptor: L-lactate dehydrogenase
Authors:Yu, L.
Deposit date:2019-01-22
Release date:2019-10-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Crystal structures ofBabesia microtilactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis.
Faseb J., 33, 2019

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數據於2024-06-26公開中

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