PDB: 46 resultsInfo pagesStatus searchChemie searchBIRD

---

4F7G	Crystal structure of talin autoinhibition complex Descriptor: Talin-1 Authors: Song, X, Qin, J, Ye, S, Zhang, R. Deposit date: 2012-05-16 Release date: 2012-07-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion. Cell Res., 22, 2012
5EJS	Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain, mutant 1 Descriptor: Myosin-I heavy chain Authors: Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2015-11-02 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc.Natl.Acad.Sci.USA, 113, 2016
6U4K	Human talin2 residues 1-403 Descriptor: Talin-2 Authors: Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K. Deposit date: 2019-08-26 Release date: 2020-07-08 Last modified: 2020-09-23 Method: X-RAY DIFFRACTION (2.555 Å) Cite: A distinct talin2 structure directs isoform specificity in cell adhesion. J.Biol.Chem., 295, 2020
1QQG	CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1 Descriptor: INSULIN RECEPTOR SUBSTRATE 1 Authors: Dhe-Paganon, S, Shoelson, S.E. Deposit date: 1999-06-04 Release date: 1999-08-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1. Proc.Natl.Acad.Sci.USA, 96, 1999
8FSE	Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain Descriptor: Integrin beta-2,Talin-1 Authors: Wu, J, Gao, T. Deposit date: 2023-01-09 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024
8FTB	Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with a K306Q mutation Descriptor: Integrin beta-2,Talin-1 Authors: Wu, J, Gao, T. Deposit date: 2023-01-11 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024
6VGU	Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin Descriptor: Integrin beta-3,Talin-1 Authors: Zhang, P, Sun, Y, Wu, J. Deposit date: 2020-01-09 Release date: 2020-12-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding. Proc.Natl.Acad.Sci.USA, 117, 2020
5EJR	Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain Descriptor: 1,2-ETHANEDIOL, Myosin-I heavy chain Authors: Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Clause, J, Titus, M.A, Houdusse, A. Deposit date: 2015-11-02 Release date: 2016-07-06 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc.Natl.Acad.Sci.USA, 113, 2016
1Y19	Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1 Authors: de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C. Deposit date: 2004-11-17 Release date: 2005-01-04 Last modified: 2016-11-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions J.Biol.Chem., 280, 2005
5MV7	Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain Descriptor: SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Unconventional myosin-VIIb Authors: Planelles-Herrero, V.J, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2017-01-15 Release date: 2017-07-05 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV9	Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain Descriptor: ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ... Authors: Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2017-01-16 Release date: 2017-07-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV8	Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain Descriptor: GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... Authors: Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2017-01-16 Release date: 2017-07-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
1MK7	CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA Descriptor: Integrin Beta3, TALIN Authors: Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. Deposit date: 2002-08-28 Release date: 2003-01-28 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
1MIX	Crystal structure of a FERM domain of Talin Descriptor: Talin Authors: Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. Deposit date: 2002-08-23 Release date: 2003-01-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural determinants of integrin recognition by talin Mol.Cell, 11, 2003
1MIZ	Crystal structure of an integrin beta3-talin chimera Descriptor: TALIN, integrin beta3 Authors: Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. Deposit date: 2002-08-23 Release date: 2003-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural determinants of integrin recognition by talin Mol.Cell, 11, 2003
1MK9	CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA Descriptor: Integrin Beta3, TALIN Authors: Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. Deposit date: 2002-08-28 Release date: 2003-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
8T0D	Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with E269A/Y270A/K306Q triple mutation Descriptor: Integrin beta-2,Talin-1 Authors: Wu, J, Gao, T. Deposit date: 2023-05-31 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024
8VDO	Cryogenic electron microscopy model of full-length talin lacking F2, R12 and FABD. Descriptor: Green fluorescent protein,Talin-1 Authors: Izard, T, Rangarajan, E.S. Deposit date: 2023-12-16 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: High-resolution snapshots of talin auto-inhibitory states To be published
8VDP	Cryogenic electron microscopy model of full-length talin without FABD Descriptor: Green fluorescent protein,Talin-1 Authors: Izard, T, Rangarajan, E.S. Deposit date: 2023-12-17 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: High-resolution snapshots of talin auto-inhibitory states To be published
8VDQ	Cryogenic electron microscopy model of full-length talin Descriptor: Green fluorescent protein,Talin-1 Authors: Izard, T, Rangarajan, E.S. Deposit date: 2023-12-17 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (5.5 Å) Cite: High-Resolution snapshots of talin auto-inhibitory states To be published
8VDR	Cryogenic electron microscopy model of full-length talin without R12 and FABD Descriptor: Green fluorescent protein,Talin-1 Authors: Izard, T, Rangarajan, E.S. Deposit date: 2023-12-17 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: High-resolution snapshots of talin auto-inhibitory states To be published

<12