PDB: 341 resultsInfo pagesStatus searchChemie searchBIRD

---

5ZMP	The structure of a lysine deacylase Descriptor: ZINC ION, lysine deacylase Authors: Ge, F. Deposit date: 2018-04-05 Release date: 2019-02-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.19 Å) Cite: The structure of a lysine deacylase To Be Published
1C3S	CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH SAHA Descriptor: HDLP (HISTONE DEACETYLASE-LIKE PROTEIN), OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ZINC ION Authors: Finnin, M.S, Donigian, J.R, Pavletich, N.P. Deposit date: 1999-07-28 Release date: 1999-09-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors. Nature, 401, 1999
3ZNS	HDAC7 bound with TFMO inhibitor tmp942 Descriptor: HISTONE DEACETYLASE 7, N-{[1-methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperidin-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ... Authors: Lobera, M, Madauss, K.P, Pohlhaus, D.T, Trump, R.P, Nolan, M.A. Deposit date: 2013-02-15 Release date: 2013-03-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group Nat.Chem.Biol., 9, 2013
1ZZ0	Crystal structure of a HDAC-like protein with acetate bound Descriptor: ACETATE ION, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... Authors: Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. Deposit date: 2005-06-13 Release date: 2005-11-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
1ZZ3	Crystal structure of a HDAC-like protein with CypX bound Descriptor: 3-CYCLOPENTYL-N-HYDROXYPROPANAMIDE, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... Authors: Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. Deposit date: 2005-06-13 Release date: 2005-11-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
1C3R	CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN A Descriptor: HDLP (HISTONE DEACETYLASE-LIKE PROTEIN), TRICHOSTATIN A, ZINC ION Authors: Finnin, M.S, Donigian, J.R, Pavletich, N.P. Deposit date: 1999-07-28 Release date: 1999-09-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors. Nature, 401, 1999
1ZZ1	Crystal structure of a HDAC-like protein with SAHA bound Descriptor: Histone deacetylase-like amidohydrolase, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, POTASSIUM ION, ... Authors: Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. Deposit date: 2005-06-13 Release date: 2005-11-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
1C3P	CRYSTAL STRUCTURE OF AN HDAC HOMOLOG FROM AQUIFEX AEOLICUS Descriptor: PROTEIN (HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)) Authors: Finnin, M.S, Donigian, J.R, Pavletich, N.P. Deposit date: 1999-07-28 Release date: 1999-09-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors. Nature, 401, 1999
6XEC	STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH KETONE INHIBITOR (COMPOUND O) Descriptor: (1S)-N-{(1S)-1-[5-cyano-2-(4-fluorophenyl)-1H-imidazol-4-yl]-7,7-dihydroxynonyl}-6-methyl-6-azaspiro[2.5]octane-1-carboxamide, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Klein, D.J, Clausen, D. Deposit date: 2020-06-12 Release date: 2020-08-12 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.701 Å) Cite: Development of a selective HDAC inhibitor aimed at reactivating the HIV latent reservoir. Bioorg.Med.Chem.Lett., 30, 2020
6XDM	STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH AN ARYL KETONE INHIBITOR Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Histone deacetylase 2, ... Authors: Klein, D.J, Liu, J. Deposit date: 2020-06-11 Release date: 2020-07-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance. Acs Med.Chem.Lett., 11, 2020
7SGG	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with SAHA Descriptor: DI(HYDROXYETHYL)ETHER, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, PHOSPHATE ION, ... Authors: Herbst-Gervasoni, C.J, Christianson, D.W. Deposit date: 2021-10-05 Release date: 2022-10-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc., 144, 2022
7SGK	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with DKFZ-728 Descriptor: N-(2-{[4-(hydroxyamino)-4-oxobutyl](methyl)amino}ethyl)benzamide, PHOSPHATE ION, POTASSIUM ION, ... Authors: Herbst-Gervasoni, C.J, Christianson, D.W. Deposit date: 2021-10-05 Release date: 2022-10-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc., 144, 2022
7SGI	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Inhibitor 14 Descriptor: 5-[(2-anilino-2-oxoethyl)(methyl)amino]-N-hydroxypentanamide, PHOSPHATE ION, POTASSIUM ION, ... Authors: Herbst-Gervasoni, C.J, Christianson, D.W. Deposit date: 2021-10-05 Release date: 2022-10-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc., 144, 2022
7SGJ	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with DKFZ-711 Descriptor: 1,2-ETHANEDIOL, 4-[(3-anilino-3-oxopropyl)(methyl)amino]-N-hydroxybutanamide, DI(HYDROXYETHYL)ETHER, ... Authors: Herbst-Gervasoni, C.J, Christianson, D.W. Deposit date: 2021-10-05 Release date: 2022-10-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc., 144, 2022
8SZU	Structure of Kdac1-Citarinostat complex from Acinetobacter baumannii Descriptor: Citarinostat, Histone deacetylase domain-containing protein, POTASSIUM ION, ... Authors: Watson, P.R, Christianson, D.W. Deposit date: 2023-05-30 Release date: 2023-09-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii . Biochemistry, 62, 2023
8SZT	Structure of Kdac1 from Acinetobacter baumannii Descriptor: CHLORIDE ION, Histone deacetylase domain-containing protein, POTASSIUM ION, ... Authors: Watson, P.R, Christianson, D.W. Deposit date: 2023-05-30 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii . Biochemistry, 62, 2023
8TQ0	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with (R)-Lipoic Acid Descriptor: DIHYDROLIPOIC ACID, Hdac6 protein, POTASSIUM ION, ... Authors: Watson, P.R, Christianson, D.W. Deposit date: 2023-08-06 Release date: 2023-09-20 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of histone deacetylase 6 complexed with (R)-lipoic acid, an essential cofactor in central carbon metabolism. J.Biol.Chem., 299, 2023
1T69	Crystal Structure of human HDAC8 complexed with SAHA Descriptor: Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ZINC ION Authors: Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. Deposit date: 2004-05-05 Release date: 2004-07-27 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases Structure, 12, 2004
1T67	Crystal Structure of Human HDAC8 complexed with MS-344 Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, SODIUM ION, ... Authors: Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. Deposit date: 2004-05-05 Release date: 2004-07-27 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases Structure, 12, 2004
1T64	Crystal Structure of human HDAC8 complexed with Trichostatin A Descriptor: CALCIUM ION, Histone deacetylase 8, SODIUM ION, ... Authors: Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. Deposit date: 2004-05-05 Release date: 2004-07-27 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases Structure, 12, 2004
1VKG	Crystal Structure of Human HDAC8 complexed with CRA-19156 Descriptor: 5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE, Histone deacetylase 8, SODIUM ION, ... Authors: Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. Deposit date: 2004-05-13 Release date: 2004-07-27 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases Structure, 12, 2004
8WZL	Arabidopsis thaliana Histone deacetylase 7 (HDA7) Descriptor: Histone deacetylase 7, SULFATE ION Authors: Saharan, K, Vasudevan, D. Deposit date: 2023-11-02 Release date: 2024-05-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure-function analyses reveal Arabidopsis thaliana HDA7 to be an inactive histone deacetylase. Curr Res Struct Biol, 7, 2024
3MEN	Crystal structure of acetylpolyamine aminohydrolase from Burkholderia pseudomallei, iodide soak Descriptor: Acetylpolyamine aminohydrolase, IODIDE ION, POTASSIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-03-31 Release date: 2010-04-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics, 12, 2011
3MAX	Crystal Structure of Human HDAC2 complexed with an N-(2-aminophenyl)benzamide Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Histone deacetylase 2, ... Authors: Skene, R.J, Jennings, A.J. Deposit date: 2010-03-24 Release date: 2010-04-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides. Bioorg.Med.Chem.Lett., 20, 2010
7WJL	Crystal structure of S. cerevisiae Hos3 Descriptor: ACETATE ION, Histone deacetylase HOS3, ZINC ION Authors: Pang, N.N, Che, S.Y, Yang, N. Deposit date: 2022-01-07 Release date: 2023-01-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural characterization of fungus-specific histone deacetylase Hos3 provides insights into developing selective inhibitors with antifungal activity. J.Biol.Chem., 298, 2022

<1234567891011121314>